Search Results - "Kwak, Seongsung"

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  1. 1

    Safety verification for polysorbate 20, pharmaceutical excipient for intramuscular administration, in Sprague-Dawley rats and New Zealand White rabbits by Kim, Junhyung, Kwak, Seongsung, Park, Mi-Sun, Rhee, Chang-Hoon, Yang, Gi-Hyeok, Lee, Jangmi, Son, Woo-Chan, Kang, Won-Ho

    Published in PloS one (27-08-2021)
    “…Human serum albumin (HSA) has been widely used as a pharmaceutical excipient in Botulinum toxin serotype A (BoNT/A) products that are indicated for use in…”
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    Journal Article
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    Model-Based Anticancer Effect of Botulinum Neurotoxin Type A1 on Syngeneic Melanoma Mice by Kang, Won-Ho, Ryu, Hyo-Jeong, Kwak, Seongsung, Yun, Hwi-Yeol

    Published in Frontiers in pharmacology (04-01-2022)
    “…In recent, Botulinum Neurotoxin A1 (BoNT/A1) has been suggested as a potential anticancer agent due to neuronal innervation in tumor cells. Although potential…”
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    Journal Article
  4. 4

    Preventive effect of Lacticaseibacillus paracasei LMT18-32 on Porphyromonas gingivalis induced periodontitis by Choi, Woo Jin, Cho, Seung Kee, Dong, Hye Jin, Kim, Tai Hoon, Soon, Jaejoon, Lee, Hyo Jin, Yoon, Kwang Ho, Kwak, Seongsung, Yun, Jiae

    Published in Food science and biotechnology (01-07-2024)
    “…Periodontitis is a severe gum infection leading to chronic inflammation in the gums, damage of tissues around teeth, and destruction of alveolar bones…”
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    Journal Article
  5. 5

    Comparative Pharmacodynamics of Three Different Botulinum Toxin Type A Preparations following Repeated Intramuscular Administration in Mice by Byun, Jaeyoon, Kwak, Seongsung, Kwon, Jin-Hee, Shin, Minhee, Lee, Dong-Kyu, Rhee, Chang-Hoon, Kang, Won-ho, Oh, Jae-Wook, Cruz, Deu John M

    Published in Toxins (25-05-2022)
    “…Botulinum neurotoxin type A (BoNT/A) causes muscle paralysis by blocking cholinergic signaling at neuromuscular junctions and is widely used to temporarily…”
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    Journal Article
  6. 6

    Model-based interspecies interpretation of botulinum neurotoxin type A on muscle-contraction inhibition by Ryu, Hyo-Jeong, Kwak, Seongsung, Park, Misun, Yun, Hwi-Yeol

    Published in Biopharmaceutics & drug disposition (19-07-2024)
    “…Botulinum neurotoxins (BoNTs) are commonly used in therapeutic and cosmetic applications. One such neurotoxin, BoNT type A (BoNT/A), has been studied widely…”
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    Journal Article
  7. 7

    Comparative Pharmacodynamics Study of 3 Different Botulinum Toxin Type A Preparations in Mice by Kwak, Seongsung, Kang, Won-ho, Rhee, Chang-Hoon, Yang, Gi-Hyeok, Cruz, Deu John M.

    Published in Dermatologic surgery (01-12-2020)
    “…BACKGROUNDA new complexing protein-free botulinum toxin Type A (CBoNT) with the same mechanism of action as the botulinum toxin complex onabotulinumtoxinA…”
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  9. 9

    Combination of PD-1 Checkpoint Blockade and Botulinum Toxin Type A1 Improves Antitumor Responses in Mouse Tumor Models of Melanoma and Colon Carcinoma by Kwak, Seongsung, Lee, Ji-Young, Kim, Min Ju, Lee, Hyo Jin, Lee, Dong-Kyu, Kang, Jiyeon, Kang, Won-ho, Son, Woo-Chan, Cruz, Deu John M.

    Published in Immunological investigations (01-11-2023)
    “…Tumor innervation has been shown to be utilized by some solid cancers to support tumor initiation, growth, progression, and metastasis, as well as confer…”
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    Journal Article
  10. 10

    Comparative Analyses of Inflammatory Response and Tissue Integration of 14 Hyaluronic Acid-Based Fillers in Mini Pigs by Choi, Min-Seo, Kwak, Seongsung, Kim, Junhyung, Park, Mi-Sun, Ko, Soo Min, Kim, Taehee, Jeong, Da Som, Rhee, Chang-Hoon, Yang, Gi-Hyeok, Son, Woo-Chan, Kang, Won-Ho

    “…Hyaluronic acid (HA)-based dermal fillers have been approved for various clinical indications, both cosmetic and medical. Previous studies that have assessed…”
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    Journal Article