Search Results - "Kvitko, Brian"
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Discovery of the Hrp Type III Secretion System in Phytopathogenic Bacteria: How Investigation of Hypersensitive Cell Death in Plants Led to a Novel Protein Injector System and a World of Inter-Organismal Molecular Interactions Within Plant Cells
Published in Phytopathology (01-04-2023)“…In the early 1960s, and other host-specific phytopathogenic proteobacteria were discovered to elicit a rapid, resistance-associated death when infiltrated at…”
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In planta transcriptomics reveals conflicts between pattern-triggered immunity and the AlgU sigma factor regulon
Published in PloS one (01-09-2022)“…In previous work, we determined the transcriptomic impacts of flg22 pre-induced Pattern Triggered Immunity (PTI) in Arabidopsis thaliana on the pathogen…”
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Transcriptome landscape of a bacterial pathogen under plant immunity
Published in Proceedings of the National Academy of Sciences - PNAS (27-03-2018)“…Plant pathogens can cause serious diseases that impact global agriculture. The plant innate immunity, when fully activated, can halt pathogen growth in plants…”
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The Genetic Requirements for HiVir-Mediated Onion Necrosis by Pantoea ananatis , a Necrotrophic Plant Pathogen
Published in Molecular plant-microbe interactions (01-06-2023)“…is an unusual bacterial pathogen that lacks typical virulence determinants yet causes extensive necrosis in onion foliage and bulb tissues. The onion necrosis…”
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Pattern-Triggered Immunity Alters the Transcriptional Regulation of Virulence-Associated Genes and Induces the Sulfur Starvation Response in Pseudomonas syringae pv. tomato DC3000
Published in Molecular plant-microbe interactions (01-07-2018)“…Pattern-triggered immunity (PTI) can confer broad defense against diverse microbes and pathogens with disparate lifestyles through the detection of microbial…”
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Single-cell profiling of Arabidopsis leaves to Pseudomonas syringae infection
Published in Cell reports (Cambridge) (25-07-2023)“…Plant response to pathogen infection varies within a leaf, yet this heterogeneity is not well resolved. We expose Arabidopsis to Pseudomonas syringae or mock…”
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AlgU, a Conserved Sigma Factor Regulating Abiotic Stress Tolerance and Promoting Virulence in Pseudomonas syringae
Published in Molecular plant-microbe interactions (01-04-2021)“…can rapidly deploy specialized functions to deal with abiotic and biotic stresses. Host niches pose specific sets of environmental challenges driven, in part,…”
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Deletions in the repertoire of Pseudomonas syringae pv. tomato DC3000 type III secretion effector genes reveal functional overlap among effectors
Published in PLoS pathogens (01-04-2009)“…The gamma-proteobacterial plant pathogen Pseudomonas syringae pv. tomato DC3000 uses the type III secretion system to inject ca. 28 Avr/Hop effector proteins…”
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Thiosulfinate Tolerance Gene Clusters Are Common Features of Burkholderia Onion Pathogens
Published in Molecular plant-microbe interactions (01-06-2024)“…pv. , , and are common bacterial pathogens of onion. Onions produce organosulfur thiosulfinate defensive compounds after cellular decompartmentalization. Using…”
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Construction of Pseudomonas syringae pv. tomato DC3000 mutant and polymutant strains
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2011)“…Redundancy between Pseudomonas syringae pv. tomato DC3000 virulence factors has made their characterization difficult. One method to circumvent redundancy for…”
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Thiosulfinate Tolerance Is a Virulence Strategy of an Atypical Bacterial Pathogen of Onion
Published in Current biology (17-08-2020)“…Unlike most characterized bacterial plant pathogens, the broad-host-range plant pathogen Pantoea ananatis lacks both the virulence-associated type III and type…”
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Shoot Maturation Strengthens FLS2-Mediated Resistance to Pseudomonas syringae
Published in Molecular plant-microbe interactions (01-12-2023)“…Temporospatial regulation of immunity components is essential for properly activating plant defense response. Flagellin-sensing 2 (FLS2) is a surface-localized…”
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Ontogenic stage-associated SA response contributes to leaf age-dependent resistance in Arabidopsis and cotton
Published in Frontiers in plant science (29-07-2024)“…As leaves grow, they transition from a low-microbe environment embedded in shoot apex to a more complex one exposed to phyllosphere microbiomes. Such change…”
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Altering cold-regulated gene expression decouples the salicylic acid-growth trade-off in Arabidopsis
Published in The Plant cell (03-10-2024)“…In Arabidopsis (Arabidopsis thaliana), overproduction of salicylic acid (SA) increases disease resistance and abiotic stress tolerance but penalizes growth…”
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Genome Context Influences Evolutionary Flexibility of Nearly Identical Type III Effectors in Two Phytopathogenic Pseudomonads
Published in Frontiers in microbiology (18-02-2022)“…Integrative Conjugative Elements (ICEs) are replicons that can insert and excise from chromosomal locations in a site-specific manner, can conjugate across…”
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RpoS contributes in a host-dependent manner to Salmonella colonization of the leaf apoplast during plant disease
Published in Frontiers in microbiology (08-11-2022)“…Contaminated fresh produce has been routinely linked to outbreaks of Salmonellosis. Multiple studies have identified factors associated with successful…”
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Genetic disassembly and combinatorial reassembly identify a minimal functional repertoire of type III effectors in Pseudomonas syringae
Published in Proceedings of the National Academy of Sciences - PNAS (15-02-2011)“…The virulence of Pseudomonas syringae and many other proteobacterial pathogens is dependent on complex repertoires of effector proteins injected into host…”
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Validation of RT-qPCR Approaches to Monitor Pseudomonas syringae Gene Expression During Infection and Exposure to Pattern-Triggered Immunity
Published in Molecular plant-microbe interactions (01-04-2018)“…Pseudomonas syringae pv. tomato DC3000 is an important model plant pathogen, with a fully annotated genome and multiple compatible plant hosts. Very few…”
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Pantailocins: phage-derived bacteriocins from Pantoea ananatis and Pantoea stewartii subsp. indologenes
Published in Applied and environmental microbiology (21-12-2023)“…Phage-derived bacteriocins (tailocins) are ribosomally synthesized structures produced by bacteria in order to provide advantages against competing strains…”
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