Search Results - "Kvetnoy, I M"
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Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells
Published in Bulletin of experimental biology and medicine (01-11-2020)“…Thymalin is a polypeptide complex isolated from the thymus and regulating the functions of the immune system. Thymalin is effective in therapy of acute…”
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Peptide Regulation of Gene Expression and Protein Synthesis in Bronchial Epithelium
Published in Lung (01-10-2014)“…Introduction Some studies have shown that peptides have high treatment potential due to their biological activity, harmlessness, and tissue-specific action…”
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Placental protein expression of kisspeptin-1 (KISS1) and the kisspeptin-1 receptor (KISS1R) in pregnancy complicated by diabetes mellitus or preeclampsia
Published in Archives of gynecology and obstetrics (01-02-2020)“…Purpose Kisspeptins regulate the trophoblast invasion. The disturbance of this process might lead to the development of preeclampsia (PE). Diabetes mellitus…”
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Sirtuins: Role in the Regulation of Oxidative Stress and the Pathogenesis of Neurodegenerative Diseases
Published in Neuroscience and behavioral physiology (2022)“…Sirtuins (SIRTs) are a family of histone deacetylases which epigenetically regulate major cell functions. This review analyzes the role of SIRTs in controlling…”
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Role of Transcription Factor NF-κB in Neuroimmunoendocrine Mechanisms of Respiratory Diseases
Published in Journal of evolutionary biochemistry and physiology (01-03-2024)“…One of the current challenges of biomedicine is to elucidate the multicomponent and multilevel mechanism of integrated neuroimmunoendocrine regulation of…”
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Interrelation of Cell Apoptosis and Proliferation in the Thymus during Its Involution
Published in Bulletin of experimental biology and medicine (01-08-2011)“…In people over 60 years, thymocytes contain proliferation protein Ki67 and proapoptotic protein P53. During aging, apoptosis of thymus cell prevails over…”
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Sirtuins as Possible Predictors of Aging and Alzheimer’s Disease Development: Verification in the Hippocampus and Saliva
Published in Bulletin of experimental biology and medicine (01-10-2020)“…Verification of signaling molecules in the saliva is a non-invasive method of diagnosis and evaluation of treatment effectiveness in different pathologies…”
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Sirtuins and Aging
Published in Neuroscience and behavioral physiology (01-11-2022)“…The sirtuin family of proteins (SIRT proteins) are involved in DNA repair, chromatin remodeling, epigenetic regulation of the expression of metabolism genes,…”
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Age-Related Features of Expression of Cell Renewal Factors in the Intestinal Peyer's Patches
Published in Bulletin of experimental biology and medicine (01-02-2011)“…Immunohistochemical study with markers of proapoptotic protein P53 and proliferation protein Ki-67 revealed an age-related decrease in proliferative activity…”
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Influence of AEDG and KE Peptides on Mitochondrial Staining and the Expression of Ribosomal Protein L7A with Aging of the Human Pineal Gland and Thymus Cell In Vitro
Published in Advances in gerontology (01-07-2021)“…New molecular targets for the geroprotective activity of AEDG (epitalon) and KE (vilon) peptides were verified via confocal laser scanning microscopy. It was…”
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The influence of AEDG and KE peptides on mitochondries stain and L7A ribosomes protein expression during human pineal gland and thymus cell senescence in vitro.
Published in Advances in gerontology = Uspekhi gerontologii (2020)“…It was verified new molecular targets of geroprotective activity of AEDG (epitalon) and KE (vilon) peptides by the method of confocal laser scanning…”
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Sirtuins Expression in the Hippocampus and Buccal Epithelium of Elderly and Senile Individuals with Alzheimer’s Disease
Published in Advances in gerontology (01-04-2021)“…Sirtuins (SIRT) are a class of NAD-dependent proteins with deacetylase activity that are involved in the regulation of transcription, metabolic pathways, and…”
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Troponins, Adhesion Molecules, and Interleukins as Diagnostic Markers of CVDs: Expression in Peripheral Tissues
Published in Biology bulletin reviews (2020)“…Cardiovascular disease (CVD) is one of the main causes of mortality for middle-aged and elderly people in developed countries. The early diagnostic of CVD in…”
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Peptide Regulation of Skin Fibroblast Functions during Their Aging In Vitro
Published in Bulletin of experimental biology and medicine (01-05-2016)“…The effect peptides KE, KED, AED and AEDG on proliferation (Ki-67), regeneration and aging (CD98hc), apoptosis (caspase-3), and extracellular matrix remodeling…”
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Molecular Aspects of the Geroprotective Effect of Peptide KE in Human Skin Fibroblasts
Published in Advances in gerontology (01-07-2018)“…Skin aging is an current problem of modern geriatric cosmetology. One promising method to decelerate the process of age-related skin changes is the use of…”
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Immunohistochemical verification of kisspeptins and their receptor in human fetal organs during prenatal development
Published in Russian journal of developmental biology (01-05-2017)“…Kisspeptins (KPs) and their receptor (KISS1R) play an important role in many physiological processes in the body, such as sexual maturation, reproductive…”
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Molecular Markers of Early Diagnosis of Alzheimer Disease: Prospects for Research in Peripheral Tissues
Published in Advances in gerontology (01-04-2018)“…Alzheimer’s disease (AD) is a progressive neurodegenerative disorder of elderly and old-aged people. Cerebrospinal fluid (CSF) and peripheral…”
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MELATONIN: THE POSSIBILITY TO ANALYSE THE MARKER OF AGE-RELATED PATHOLOGY IN THE BUCCAL EPITHELIUM AND URINE
Published in Klinicheskaia meditsina (2017)“…Extrapineal and pineal melatonin is the marker of the aging rate of organism making it possible to characterize functional condition of the…”
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DIFFUSE NEUROENDOCRINE SYSTEM OF THE STOMACH AND CHARACTERISTICS OF PROLIFERATION IN REALIZATION OF CORREA'S CASCADE IN DISEASES ASSOCIATED WITH HELICOBACTER PYLORI
Published in Klinicheskaia meditsina (2015)“…To study the role of the vascular endothelial growth factor (VEGF), Ki-67, BCL-2, and endocrine cells (EC) of gastric mucosa producing somatostatin (SS),…”
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