Search Results - "Kvanta, A."
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Human ex vivo model of iris angiogenesis
Published in Acta ophthalmologica (Oxford, England) (01-09-2017)“…Purpose To assess iris angiogenesis using human explants and determine the role of hypoxia during iris neovascularization. Methods Human irises were isolated…”
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Differential hypoxic response of human choroidal and retinal endothelial cells proposes tissue heterogeneity of ocular angiogenesis
Published in ACTA OPHTHALMOLOGICA (01-09-2017)“…Purpose To elaborate molecular differences between choroidal and retinal angiogenesis by generating and comparatively analyzing human primary choroidal and…”
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3
Differential hypoxic response of human choroidal and retinal endothelial cells proposes tissue heterogeneity of ocular angiogenesis
Published in Acta ophthalmologica (Oxford, England) (01-10-2016)“…Purpose To elaborate molecular differences between choroidal and retinal angiogenesis by generating and comparatively analyzing human primary choroidal and…”
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4
A novel in vivo model of puncture‐induced iris neovascularization
Published in ACTA OPHTHALMOLOGICA (01-09-2017)“…Purpose To assess iris neovascularization by uveal puncture of the mouse eye and determine the role of angiogenic factors during iris neovascularization…”
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5
Complement system proteins in human embryonic stem cell-derived retinal pigment epithelial cells co-cultured with or without porcine retina
Published in MOLECULAR IMMUNOLOGY (2017)Get full text
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6
Gene therapy strategies for hypoxia‐inducible angiogenesis in ocular neovascularization
Published in ACTA OPHTHALMOLOGICA (01-09-2017)“…Purpose Our previous results have associated HIF expression in RPE cells to CNV progression, and we have shown that gene transfer of prolyl hydroxylase domain…”
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Diagnostic incisional biopsies in clinically indeterminate choroidal tumours
Published in Eye (London) (01-02-2013)“…Most intraocular tumours are reliably diagnosed by a careful clinical examination combined with one or more non-invasive diagnostic techniques. However, in a…”
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Gene transfer of prolyl hydroxylase domain 2 inhibits hypoxia‐inducible angiogenesis in a model of choroidal neovascularization
Published in Acta ophthalmologica (Oxford, England) (01-10-2016)“…Purpose Cellular responses to hypoxia are mediated by the hypoxia‐inducible factors (HIF). In normoxia, HIF‐α proteins are tightly regulated by a family of…”
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A prospective randomised study on low-dose transpupillary thermotherapy versus photodynamic therapy for neovascular age-related macular degeneration
Published in British journal of ophthalmology (01-06-2008)“…To compare the efficacy of low-dose transpupillary thermotherapy (TTT) and verteporfin photodynamic therapy (PDT) in patients with occult neovascular…”
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Identification of HIF-1α regulated microRNAs in a mouse model of oxygen-induced retinopathy
Published in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2023)Get full text
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Matrix metalloproteinase (MMP) expression in experimental choroidal neovascularization
Published in Current eye research (2000)“…Purpose. Matrix metalloproteinases (MMP) are a family of proteolytic enzymes that degrade basement membrane and extracellular matrix proteins. To gain…”
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Hypoxia-Inducible Factor-1α Is Associated With Sprouting Angiogenesis in the Murine Laser-Induced Choroidal Neovascularization Model
Published in Investigative ophthalmology & visual science (01-10-2015)“…To investigate the expression and distribution of neoangiogenic molecules and the role of hypoxia during the development of experimental choroidal…”
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Accelerated maturation of ARPE‐19 cells for the translational assessment of gene therapy
Published in The FASEB journal (15-09-2024)“…The human retinal pigment epithelium (RPE) cell line ARPE‐19 is widely used as an alternative to primary RPE despite losing many features of primary RPE. We…”
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Optical Coherence Tomography Angiography in Central Retinal Vein Occlusion: Correlation Between the Foveal Avascular Zone and Visual Acuity
Published in Investigative ophthalmology & visual science (01-07-2016)“…To investigate the relationship between best-corrected visual acuity (BCVA) and the foveal avascular zone (FAZ) in patients with central retinal vein occlusion…”
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Translational assessment of gene therapy in maturated ARPE-19 cells
Published in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2023)Get full text
Conference Proceeding -
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Transcriptome Analysis Indicates Hypoxia-Inducible Factor-1alpha as a Key Regulator of Choroidal Neovascularization
Published in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2023)Get full text
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17
Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin
Published in eLife (21-04-2020)“…Edema stemming from leaky blood vessels is common in eye diseases such as age-related macular degeneration and diabetic retinopathy. Whereas therapies…”
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miRNAs as putative biomarkers for recurrent hemorrhage after PPV
Published in ACTA OPHTHALMOLOGICA (01-12-2018)Get full text
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19
Drusen maculopathy: a risk factor for visual deterioration
Published in Acta ophthalmologica (Oxford, England) (01-08-2016)“…Age‐related macular degeneration (AMD), the most common cause of visual loss after the age of 65, displays a degeneration of the retinal pigment epithelial…”
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Mitigation of human iris angiogenesis through uPAR/LRP‐1 interaction antagonism in an organotypic ex vivo model
Published in The FASEB journal (15-03-2024)“…Rubeosis Iridis (RI) is characterized by an increase in neovascularization and inflammation factors in the iris. During angiogenesis, the urokinase plasminogen…”
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