Search Results - "Kvamme, E"
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Synthesis of glutamate and its regulation
Published in Progress in brain research (1998)Get more information
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Novel Form of Phosphate Activated Glutaminase in Cultured Astrocytes and Human Neuroblastoma Cells, PAG in Brain Pathology and Localization in the Mitochondria
Published in Neurochemical research (01-07-2008)“…A novel form of phosphate activated glutaminase (PAG), catalyzing the synthesis of glutamate from glutamine, has been detected in cultured astrocytes and…”
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Kinetics of a Novel Isoform of Phosphate Activated Glutaminase (PAG) in SH-SY5Y Neuroblastoma Cells
Published in Neurochemical research (01-06-2010)“…We have recently found that the neuroblastoma cell line SH-SY5Y expresses a novel form of phosphate activated glutaminase (PAG) which deamidates glutamine to…”
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Postembedding immunogold labelling reveals subcellular localization and pathway-specific enrichment of phosphate activated glutaminase in rat cerebellum
Published in Neuroscience (01-02-1999)“…Phosphate activated glutaminase is a key enzyme in glutamate synthesis. Here we have employed a quantitative and high resolution immunogold procedure to…”
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Evidence indicating that pig renal phosphate-activated glutaminase has a functionally predominant external localization in the inner mitochondrial membrane
Published in The Journal of biological chemistry (15-07-1991)“…Phosphate-activated glutaminase in intact pig renal mitochondria was inhibited 50-70% by the sulfhydryl reagents mersalyl and N-ethylmaleimide (0.3-1.0 mM),…”
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Glutaminase in neurons and astrocytes cultured from mouse brain: kinetic properties and effects of phosphate, glutamate, and ammonia
Published in Neurochemical research (01-04-1988)“…Phosphate activated glutaminase comprises two kinetically distinguishable enzyme forms in cultures of cerebellar granule cells, of cortical neurons and of…”
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Regulation of glutaminase and its possible implication for GABA metabolism
Published in Advances in experimental medicine and biology (1979)Get more information
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Regulation of pig kidney phosphate-activated glutaminase
Published in Contributions to nephrology (1982)Get more information
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Regulation of glutaminase by exogenous glutamate, ammonia and 2-oxoglutarate in synaptosomal enriched preparation from rat brain
Published in Neurochemical research (01-06-1982)“…Phosphate activated glutaminase in synaptosomal enriched preparation from rat brain is very sensitive to inhibition by low concentration of glutamate, ammonia…”
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Phosphate activated glutaminase activity and glutamine uptake in primary cultures of astrocytes
Published in Journal of neurochemistry (01-03-1979)Get more information
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An overview of mitochondrial glutamine transport and phosphate-activated glutaminase in the kidney
Published in Contributions to nephrology (01-01-1997)Get more information
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Properties of phosphate activated glutaminase in astrocytes cultured from mouse brain
Published in Neurochemical research (01-06-1982)“…Astrocytes in primary cultures contain a relatively high activity of phosphate activated glutaminase, although it is significantly lower than that of…”
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Ontogenetic development of glutamate metabolizing enzymes in cultured cerebellar granule cells and in cerebellum in vivo
Published in Neurochemical research (1985)“…The ontogenetic development of the enzymes phosphate activated glutaminase (PAG), glutamate dehydrogenase (GLDH), glutamic-oxaloacetic-transaminase (GOT),…”
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Synthesis of transmitter glutamate and the glial-neuron interrelationship
Published in Molecular and chemical neuropathology (1990)“…Glutamate in glutamatergic neurons exists in a cytosolic pool, as well as a transmitter pool, which is assumed to be localized in synaptic vesicles…”
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Properties of the pig renal mitochondrial glutamine transporter
Published in Contributions to nephrology (1994)Get more information
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Kinetics and localization of brain phosphate activated glutaminase
Published in Journal of neuroscience research (01-12-2001)“…The cellular concentration of phosphate, the main activator of phosphate activated glutaminase (PAG) is rather constant in brain and kidney. The enzyme…”
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Evidence for two species of mammalian phosphate-activated glutaminase having different regulatory properties
Published in FEBS letters (01-11-1979)Get full text
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Evidence for compartmentalization of glutamate in rat brain synaptosomes using the glutamate sensitivity of phosphate-activated glutaminase as a functional test
Published in Neuroscience letters (01-09-1981)“…The glutamate content of rat brain synaptosomes was measured by high performance liquid chromatography to be 39 micromol/g protein. If uncompartmentalized this…”
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Evidence for compartmentation of synaptosomal phosphate-activated glutaminase
Published in Journal of neurochemistry (01-06-1981)“…Phosphate-activated glutaminase (EC 3.5.1.2) in synaptosomal preparations is inhibited 40-60% by the sulphydryl group reagent N-ethylmaleimide (NEM), forming…”
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