Search Results - "Kuznetsov, Nikita"
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Power considerations for the application of detrended fluctuation analysis in gait variability studies
Published in PloS one (21-03-2017)“…The assessment of gait variability using stochastic signal processing techniques such as detrended fluctuation analysis (DFA) has been shown to be a sensitive…”
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The Role of Active-Site Plasticity in Damaged-Nucleotide Recognition by Human Apurinic/Apyrimidinic Endonuclease APE1
Published in Molecules (Basel, Switzerland) (28-08-2020)“…Human apurinic/apyrimidinic (AP) endonuclease APE1 hydrolyzes phosphodiester bonds on the 5' side of an AP-site, and some damaged nucleotides such as…”
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3
Kinetic Features of 3'-5' Exonuclease Activity of Human AP-Endonuclease APE1
Published in Molecules (Basel, Switzerland) (21-08-2018)“…Human apurinic/apyrimidinic (AP)-endonuclease APE1 is one of the key enzymes taking part in the repair of damage to DNA. The primary role of APE1 is the…”
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Conformational Dynamics of Biopolymers in the Course of Their Interaction: Multifaceted Approaches to the Analysis by the Stopped-Flow Technique with Fluorescence Detection
Published in Photonics (01-09-2023)“…This review deals with modern approaches to systematic research on molecular-kinetic mechanisms of damage recognition and removal by pro- and eukaryotic…”
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Structural and Molecular Kinetic Features of Activities of DNA Polymerases
Published in International journal of molecular sciences (07-06-2022)“…DNA polymerases catalyze DNA synthesis during the replication, repair, and recombination of DNA. Based on phylogenetic analysis and primary protein sequences,…”
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Dealkylation of Macromolecules by Eukaryotic α-Ketoglutarate-Dependent Dioxygenases from the AlkB-like Family
Published in Current issues in molecular biology (20-09-2024)“…Alkylating modifications induced by either exogenous chemical agents or endogenous metabolites are some of the main types of damage to DNA, RNA, and proteins…”
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The influence of a vibrotactile biofeedback system on postural dynamics during single-leg standing in healthy older adults
Published in Neuroscience letters (24-08-2022)“…•Vibrotactile biofeedback (BF) system was applied for older adults’ balance training.•Center of pressure data were analyzed via multiscale detrended…”
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Insights into Mechanisms of Damage Recognition and Catalysis by APE1-like Enzymes
Published in International journal of molecular sciences (14-04-2022)“…Apurinic/apyrimidinic (AP) endonucleases are the key DNA repair enzymes in the base excision repair (BER) pathway, and are responsible for hydrolyzing…”
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The Role of Natural Polymorphic Variants of DNA Polymerase β in DNA Repair
Published in International journal of molecular sciences (21-02-2022)“…DNA polymerase β (Polβ) is considered the main repair DNA polymerase involved in the base excision repair (BER) pathway, which plays an important part in the…”
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Pre-steady-state kinetic and mutational insights into mechanisms of endo- and exonuclease DNA processing by mutant forms of human AP endonuclease
Published in Biochimica et biophysica acta. General subjects (01-12-2022)“…Human apurinic/apyrimidinic endonuclease APE1 catalyzes endonucleolytic hydrolysis of phosphodiester bonds on the 5′ side of structurally unrelated damaged…”
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11
DNA Demethylation in the Processes of Repair and Epigenetic Regulation Performed by 2-Ketoglutarate-Dependent DNA Dioxygenases
Published in International journal of molecular sciences (01-10-2021)“…Site-specific DNA methylation plays an important role in epigenetic regulation of gene expression. Chemical methylation of DNA, including the formation of…”
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Coordination between human DNA polymerase β and apurinic/apyrimidinic endonuclease 1 in the course of DNA repair
Published in Biochimie (01-01-2024)“…Coordination of enzymatic activities in the course of base excision repair (BER) is essential to ensure complete repair of damaged bases. Two major mechanisms…”
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An Insight into the Mechanism of DNA Cleavage by DNA Endonuclease from the Hyperthermophilic Archaeon Pyrococcus furiosus
Published in International journal of molecular sciences (15-08-2024)“…Hyperthermophilic archaea such as survive under very aggressive environmental conditions by occupying niches inaccessible to representatives of other domains…”
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14
The effect of attentional focus on movement accuracy in an immersive and interactive virtual reality environment
Published in Neuroscience letters (01-05-2021)“…•We showed a simple manipulation of verbal cues affected performance accuracy in Fitts’ Law task.•Directing attention to an intended effect improved…”
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The mechanism of damage recognition by apurinic/apyrimidinic endonuclease Nfo from Escherichia coli
Published in Biochimica et biophysica acta. General subjects (01-11-2022)Get full text
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Neuromotor changes in participants with a concussion history can be detected with a custom smartphone app
Published in PloS one (15-12-2022)“…Neuromotor dysfunction after a concussion is common, but balance tests used to assess neuromotor dysfunction are typically subjective. Current objective…”
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Common Kinetic Mechanism of Abasic Site Recognition by Structurally Different Apurinic/Apyrimidinic Endonucleases
Published in International journal of molecular sciences (18-08-2021)“…Apurinic/apyrimidinic (AP) endonucleases Nfo ( ) and APE1 (human) represent two conserved structural families of enzymes that cleave AP-site-containing DNA in…”
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Substrate specificity of human apurinic/apyrimidinic endonuclease APE1 in the nucleotide incision repair pathway
Published in Nucleic acids research (30-11-2018)“…Abstract Human apurinic/apyrimidinic (AP) endonuclease APE1 catalyses the hydrolysis of phosphodiester bonds on the 5′ side of an AP-site (in the base excision…”
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The Role of DNMT Methyltransferases and TET Dioxygenases in the Maintenance of the DNA Methylation Level
Published in Biomolecules (Basel, Switzerland) (04-09-2024)“…This review deals with the functional characteristics and biological roles of enzymes participating in DNA methylation and demethylation as key factors in…”
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Conformational Dynamics of Human ALKBH2 Dioxygenase in the Course of DNA Repair as Revealed by Stopped-Flow Fluorescence Spectroscopy
Published in Molecules (Basel, Switzerland) (01-08-2022)“…Elucidation of physicochemical mechanisms of enzymatic processes is one of the main tasks of modern biology. High efficiency and selectivity of enzymatic…”
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