Search Results - "Kuzikov, Alexey V."

From electrochemistry to enzyme kinetics of cytochrome P450 by Shumyantseva, Victoria V., Kuzikov, Alexey V., Masamrekh, Rami A., Bulko, Tatiana V., Archakov, Alexander I.

“…This review is an attempt to describe advancements in the electrochemistry of cytochrome P450 enzymes (EC 1.14.14.1) and to study molecular aspects and…”
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Bielectrode Strategy for Determination of CYP2E1 Catalytic Activity: Electrodes with Bactosomes and Voltammetric Determination of 6-Hydroxychlorzoxazone by Kuzikov, Alexey V, Masamrekh, Rami A, Filippova, Tatiana A, Tumilovich, Anastasiya M, Strushkevich, Natallia V, Gilep, Andrei A, Khudoklinova, Yulia Yu, Shumyantseva, Victoria V

“…We describe a bielectrode system for evaluation of the electrocatalytic activity of cytochrome P450 2E1 (CYP2E1) towards chlorzoxazone. One electrode of the…”
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Rational Design of Amphiphilic Diblock Copolymer/MWCNT Surface Modifiers and Their Application for Direct Electrochemical Sensing of DNA by Sigolaeva, Larisa V., Bulko, Tatiana V., Konyakhina, Apollinariya Yu, Kuzikov, Alexey V., Masamrekh, Rami A., Max, Johannes B., Köhler, Moritz, Schacher, Felix H., Pergushov, Dmitry V., Shumyantseva, Victoria V.

“…We demonstrate the application of amphiphilic ionic poly(n-butylmethacrylate)-block- poly(2-(dimethylamino)ethyl methacrylate) diblock copolymers…”
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Electrosynthesis and binding properties of molecularly imprinted poly-o-phenylenediamine for selective recognition and direct electrochemical detection of myoglobin by Shumyantseva, Victoria V., Bulko, Tatiana V., Sigolaeva, Larisa V., Kuzikov, Alexey V., Archakov, Alexander I.

“…Electrosynthesis of molecularly imprinted polymer (MIP) templated with myoglobin (Mb) and the reference non-imprinted polymer (NIP) was examined with…”
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Electrochemical determination of (S)-7-hydroxywarfarin for analysis of CYP2C9 catalytic activity by Kuzikov, Alexey V., Filippova, Tatiana A., Masamrekh, Rami A., Shumyantseva, Victoria V.

“…[Display omitted] •Electrooxidation of (S)-7-hydroxywarfarin was investigated.•Electroanalytical characteristics of (S)-7-hydroxywarfarin were…”
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Biotransformation of phenytoin in the electrochemically-driven CYP2C19 system by Kuzikov, Alexey V., Filippova, Tatiana A., Masamrekh, Rami A., Shumyantseva, Victoria V.

“…The possibility of the detection of atypical kinetic profiles of drug biotransformation using electrochemical systems based on immobilized cytochromes P450…”
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The multifaceted role of proteases and modern analytical methods for investigation of their catalytic activity by Filippova, Tatiana A., Masamrekh, Rami A., Khudoklinova, Yulia Yu, Shumyantseva, Victoria V., Kuzikov, Alexey V.

“…We discuss the diverse functions of proteases in the context of their biotechnological and medical significance, as well as analytical approaches used to…”
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Electrochemical biosensor for trypsin activity assay based on cleavage of immobilized tyrosine-containing peptide by Filippova, Tatiana A., Masamrekh, Rami A., Shumyantseva, Victoria V., Latsis, Ivan A., Farafonova, Tatiana E., Ilina, Irina Y., Kanashenko, Sergey L., Moshkovskii, Sergei A., Kuzikov, Alexey V.

“…In this work, we proposed a biosensor for trypsin proteolytic activity assay using immobilization of model peptides on screen-printed electrodes (SPE) modified…”
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Molecular imprinting coupled with electrochemical analysis for plasma samples classification in acute myocardial infarction diagnostic by Shumyantseva, Victoria V., Bulko, Tatiana V., Sigolaeva, Larisa V., Kuzikov, Alexey V., Pogodin, Pavel V., Archakov, Alexander I.

“…Electroanalysis of myoglobin (Mb) in 10 plasma samples of healthy donors (HDs) and 14 plasma samples of patients with acute myocardial infarction (AMI) was…”
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All-electrochemical nanocomposite two-electrode setup for quantification of drugs and study of their electrocatalytical conversion by cytochromes P450 by Shumyantseva, Victoria V., Bulko, Tatiana V., Kuzikov, Alexey V., Masamrekh, Rami A., Konyakhina, Apollinariya Yu, Romanenko, Iuliia, Max, Johannes B., Köhler, Moritz, Gilep, Andrei A., Usanov, Sergey A., Pergushov, Dmitry V., Schacher, Felix H., Sigolaeva, Larisa V.

“…This paper describes the electrochemical behavior and an electrooxidative method for the determination of diclofenac, DF,…”
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Electrochemical studies of the interaction of rifampicin and nanosome/rifampicin with dsDNA by Shumyantseva, Victoria V., Bulko, Tatiana V., Tikhonova, Elena G., Sanzhakov, Maxim A., Kuzikov, Alexey V., Masamrekh, Rami A., Pergushov, Dmitry V., Schacher, Felix H., Sigolaeva, Larisa V.

“…•The direct electrochemistry of dsDNA was used for in situ monitoring of the drug-DNA interaction.•Rifampicin (RF) and nanosome/rifampicin (NRF) interact with…”
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Electrochemical oxidation of estrogens as a method for CYP19A1 (aromatase) electrocatalytic activity determination by Kuzikov, Alexey V., Masamrekh, Rami A., Filippova, Tatiana A., Haurychenka, Yaraslau I., Gilep, Andrei A., Shkel, Tatsiana V., Strushkevich, Natallia V., Usanov, Sergey A., Shumyantseva, Victoria V.

“…In this study we present an original approach for determination of electrocatalytic activity of CYP19A1 (aromatase), immobilized on screen-printed graphite…”
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Electroanalysis of 4′-Hydroxydiclofenac for CYP2C9 Enzymatic Assay by Kuzikov, Alexey V., Filippova, Tatiana A., Masamrekh, Rami A., Shumyantseva, Victoria V.

“…In this work, we have investigated the electrochemical properties of 4′-hydroxydiclofenac, which is the main product of cytochrome P450 2C9 (CYP2C9)-dependent…”
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Voltammetric Analysis of (S)-O-Desmethylnaproxen for Determination of CYP2C9 Demethylase Activity by Filippova, Tatiana A., Masamrekh, Rami A., Shumyantseva, Victoria V., Khudoklinova, Yulia Yu, Kuzikov, Alexey V.

“…This study demonstrates, for the first time, the potential of voltammetric analysis to detect the major metabolite of a non-steroidal anti-inflammatory drug…”
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Electrochemical Assessment of CYP3A4 Catalytic Activity in Bactosomes by Koroleva, Polina I., Kuzikov, Alexey V., Gilep, Andrei A., Bulko, Tatiana V., Shumyantseva, Victoria V.

“…In this work, we present investigation on the behavior of bactosomes containing human cytochrome CYP3A4 in comparison with recombinant enzyme. The bactosomes…”
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Interactions of galeterone and its 3‐keto‐Δ4 metabolite (D4G) with one of the key enzymes of corticosteroid biosynthesis – steroid 21‐monooxygenase (CYP21A2) by Masamrekh, Rami A., Filippova, Tatiana A., Sherbakov, Kirill A., Veselovsky, Alexander V., Shumyantseva, Victoria V., Kuzikov, Alexey V.

“…We have investigated interactions of galeterone and its pharmacologically active metabolite – 3‐keto‐Δ4‐galeterone (D4G) – with one of the key enzymes of…”
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Electroanalysis of Biomolecules: Rational Selection of Sensor Construction by Shumyantseva, Victoria V., Agafonova, Lubov E., Bulko, Tatiana V., Kuzikov, Alexey V., Masamrekh, Rami A., Yuan, Jiayin, Pergushov, Dmitry V., Sigolaeva, Larisa V.

“…Methods of electrochemical analysis of biological objects based on the reaction of electro-oxidation/electro-reduction of molecules are presented. Polymer…”
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The interactions of a number of steroid-metabolizing cytochromes P450 with abiraterone D4A metabolite: spectral analysis and molecular docking by Masamrekh, Rami A., Filippova, Tatiana A., Haurychenka, Yaraslau I., Sherbakov, Kirill A., Veselovsky, Alexander V., Shumyantseva, Victoria V., Kuzikov, Alexey V.

“…•D4A induces type I spectral changes of CYP51A1.•D4A does not interact with CYP11A1, unlike abiraterone.•D4A induces type II spectral changes of CYP19A1. The…”
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Scrutiny of electrochemically-driven electrocatalysis of C-19 steroid 1α-hydroxylase (CYP260A1) from Sorangium cellulosum So ce56 by Kuzikov, Alexey V., Masamrekh, Rami A., Khatri, Yogan, Zavialova, Maria G., Bernhardt, Rita, Archakov, Alexander I., Shumyantseva, Victoria V.

“…Direct electrochemistry and bioelectrocatalysis of a newly discovered C-19 steroid 1α-hydroxylase (CYP260A1) from the myxobacterium Sorangium cellulosum So…”
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Comparison of [17(20)E]-21-Norpregnene oxazolinyl and benzoxazolyl derivatives as inhibitors of CYP17A1 activity and prostate carcinoma cells growth by Zolottsev, Vladimir A., Tkachev, Yaroslav V., Latysheva, Alexandra S., Kostin, Vladimir A., Novikov, Roman A., Timofeev, Vladimir P., Morozevich, Galina E., Kuzikov, Alexey V., Shumyantseva, Victoria V., Misharin, Alexander Y.

“…[Display omitted] •Synthesis of oxazolinyl and benzoxazolyl derivatives of [17(20)E]-21-norpregnene.•Inhibition of CYP17A1 activity.•Computational modeling of…”
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