Search Results - "Kuzikov, A V"
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Interaction of Abiraterone and Its Pharmacologically Active Metabolite D4A with Cytochrome P450 2C9 (CYP2C9)
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (01-12-2022)“…We studied the interaction of the antitumor agent abiraterone and its pharmacologically active metabolite D4A, which is promising for use as an agent for the…”
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2
Enzymology on an Electrode and in a Nanopore: Analysis Algorithms, Enzyme Kinetics, and Perspectives
Published in BioNanoScience (01-12-2022)“… Enzymes are powerful and effective biological catalysts demanded in various areas of human activity, especially in medicinal area and as modem diagnostic…”
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Modification of Cysteine Residues for Mass Spectrometry-Based Proteomic Analysis: Facts and Artifacts
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (01-07-2020)“…Mass spectrometric proteomic analysis at the sample preparation stage involves the artificial reduction of disulfide bonds in proteins formed between cysteine…”
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Methods for Determination of Functional Activity of Cytochrome P450 Isoenzymes
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (01-07-2018)“…The review deals with modern methods and technologies for determination of functional activity cytochrome P450 isoenzymes; these include absorbance and…”
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A New Method for Quantitative Determination of Steroid Metabolites of Cytochrome P450-Dependent Reactions Using Fluorescent Spectroscopy
Published in Doklady. Biochemistry and biophysics (01-11-2018)“…A method for determination of hydroxylase activity of cytochrome P450 3A4 (CYP3A4) towards its substrate hydrocortisone using fluorescent analysis of the…”
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Cytochrome P450 3A4 as a Drug Metabolizing Enzyme: the Role of Sensor System Modifications in Electocatalysis and Electroanalysis
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (01-07-2020)“…The electroanalytical characteristics of the recombinant cytochrome P450 3A4 (CYP3A4) immobilized on the surface of screen-printed graphite electrodes modified…”
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Modeling of Drug-Drug Interactions between Omeprazole and Erythromycin in the Cytochrome P450-Dependent System In vitro
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (2021)“…In the present study an electrochemical system based on recombinant cytochrome P450 3A4 (CYP3A4) has been developed for analysis of potential drug-drug…”
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Polymer matrices with molecular memory as affine adsorbents for the determination of myoglobin as a cardiac marker of acute myocardial infarction by voltammetry
Published in Journal of analytical chemistry (New York, N.Y.) (01-04-2017)“…A possibility of myoglobin determination using screen-printed graphite electrodes modified with a poly( o -phenylenediamine)-based molecularly imprinted…”
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Oxazoline derivatives of [17(20)E]-21-norpregnene – inhibitors of CYP17A1 activity and proliferation of prostate carcinoma cells
Published in Russian chemical bulletin (01-04-2018)“…Nine new oxazolinyl derivatives of [17(20) E ]-21-norpregnene, differing in the structure of steroid moiety, were investigated for their potency to inhibit the…”
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10
Taurine modulates catalytic activity of cytochrome P450 3A4
Published in Biochemistry (Moscow) (01-03-2015)“…The influence of the biologically active compound taurine on the stability and catalytic properties of the hemoprotein cytochrome P450 3A4 has been…”
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11
Electroanalysis of myoglobin based on electropolymerized molecularly imprinted polymer poly-o-phenylenediamine and carbon nanotubes/screen printed electrode
Published in Doklady. Biochemistry and biophysics (01-05-2016)“…Electroanalysis of myoglobin as a marker of acute myocardial infarction by means of screenprinted electrodes modified with multiwalled carbon nanotubes and…”
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12
Sensors for analysis of drugs, drug-drug interactions, and catalytic activity of enzymes
Published in Bulletin of RSMU (01-02-2022)“…Development of highly sensitive methods for drug analysis is an ongoing challenge posed by modern bioanalytical and pharmaceutical chemistry. Drug analysis is…”
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Electrosynthesis and binding properties of molecularly imprinted poly-o-phenylenediamine as artificial antibodies for electroanalysis of myoglobin
Published in Doklady. Biochemistry and biophysics (01-09-2015)“…Molecularly imprinted poly-o-phenylenediamine with template myoglobin molecules (i.e., polymeric antibodies to myoglobin, molecularly imprinted polymer, MIP)…”
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14
Development of methods for functionalization of screen printed electrodes with biocompatible organic-inorganic hybrid nanocomposites for biosensing applications
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (01-07-2014)“…New types of organic-inorganic hybrid nanocomposites based on nanosized titanium oxide(IV) (TiO 2 , particle size <100 nm) and carbon nanotubes (CNT, outer…”
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Electrochemical methods in biomedical studies
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (01-07-2015)“…Own experimental studies on the development of highly sensitive methods of electrochemical analysis applicable for biochemical research in the postgenomic era…”
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Functionalization of screen printed electrodes with organic-inorganic hybrid nano-composites for bio-sensing applications
Published in Biomeditsinskaia khimiia (01-07-2015)“…New types of organic-inorganic hybrid nanocomposites based on nanosized Titanium (IV) oxide TiO2 (<100 nm particle size) and carbon nanotubes (CNT, outer…”
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Interaction of novel oxazoline derivatives of 17(20)E-pregna-5,17(20)-diene with cytochrome P450 17A1
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (01-04-2015)“…In order to find novel inhibitors of 17α-hydroxylase-17,20-lyase (cytochrome P450 17A1, CYP17A1), a key enzyme of biosynthesis of androgens, molecular docking…”
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Protein-protein interactions in the systems of cytochromes P450 3A4 and 3A5
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (01-07-2014)“…Molecular interactions between protein partners of the monooxygenase system involved in drug biotransformation (cytochromes P450 3A4, 3A5 and cytochrome b 5 )…”
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Protein-protein interactions of cytochromes P450 3A4 and 3A5 with their intermediate redox partners cytochromes b5
Published in Biomeditsinskaia khimiia (01-07-2015)“…Molecular interactions between proteins redox partners (cytochromes Р450 3А4, 3А5 and cytochrome b5) within the monooxygenase system, which is known to be…”
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Protein-protein interactions of cytochromes P450 3A4 and 3A5 with their intermediate redox partners cytochromes b5
Published in Biomeditsinskaia khimiia (01-01-2014)“…Molecular interactions between proteins redox partners (cytochromes P450 3A4, 3A5 and cytochrome b5) within the monooxygenase system, which is known to be…”
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