Search Results - "Kuze, J."

Evaluation of animal models for intestinal first-pass metabolism of drug candidates to be metabolized by CYP3A enzymes via in vivo and in vitro oxidation of midazolam and triazolam by Kuze, J., Mutoh, T., Takenaka, T., Oda, N., Hanioka, N., Narimatsu, S.

“…Abstract 1. To search an appropriate evaluation methodology for the intestinal first-pass metabolism of new drug candidates, grapefruit juice (GFJ)- and…”
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Separate evaluation of intestinal and hepatic metabolism of three benzodiazepines in rats with cannulated portal and jugular veins: comparison with the profile in non-cannulated mice by Kuze, J., Mutoh, T., Takenaka, T., Morisaki, K., Nakura, H., Hanioka, N., Narimatsu, S.

“…Pharmacokinetic analyses of three kinds of benzodiazepines-midazolam (MDZ), triazolam (TRZ) and alprezolam (APZ)-were performed in rats with cannulated portal…”
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Subjective evaluation of visual fatigue caused by motion images by Kuze, J., Ukai, K.

“…A questionnaire was developed to subjectively assess visual fatigue caused by viewing various types of motion images. The questionnaire was evaluated using…”
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FACTORS RELATED TO MENTAL HEALTH OF ELDER FAMILY CAREGIVERS IN DEMENTIA CARE by Okumura, Y., Kuze, J., Tanimukai, S.

“…In dementia care, elder caregivers increase recently and it’s necessary to consider support according to the age of the caregivers. In this study, the degree…”
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Subjective evaluation of visual fatigue caused by motion images: Health and safety aspects of visual displays by KUZE, J, UKAI, K

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Binocular Rivalry Alternation Rate Declines with Age by Ukai, Kazuhiko, Ando, Haruna, Kuze, Junko

“…The effect of aging on the time of spontaneous perceptual alternation in binocular rivalry was examined in 59 subjects. An earlier study reported the change of…”
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Sedative and hypnotic activities of pyrimidine nucleoside derivatives by Kimura, T, Teraoka, S, Kuze, J, Watanabe, K, Kondo, S, Ho, I K, Yamamoto, I

“…N3-Substituted pyrimidine nucleoside and their related compounds were synthesized. The central nervous system (CNS) depressant effect of the compounds such as…”
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The nucleoside derivatives possessing sedative and hypnotic effects by Kimura, T, Kuze, J, Watanabe, K, Yamamoto, I, Ueda, T, Katagiri, N, Kaneko, C, Tateoka, Y, Kondo, S

“…N3-Substituted oxopyrimidines and their related compounds were synthesized. The central nervous system (CNS) depressant activities of the compounds such as…”
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QTL analysis for plant and grain characters of Sake-brewing rice using a doubled haploid population by Yoshida, S. (Hyogo-ken. Research Center for Agriculture, Forestry and Fisheries, Kasai (Japan)), Ikegami, M, Kuze, J, Sawada, K, Hashimoto, Z, Ishii, T, Nakamura, C, Kamijima, O

“…Rice (Oryza sativa L.) varieties used for brewing sake are commonly characterized by traits such as large grain size with white-core (an opaque structure…”
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N super(3)-phenacyluridine: A novel hypnotic compound, interacts with the benzodiazepine receptor by Kimura, T, Kuze, J, Watanabe, K, Kondo, S, Ho, I K, Yamamoto, I

“…N super(3)-Phenacyluridine (3-phenacyl-1- beta -D-ribofuranosyluracil) has potent sedative and hypnotic activities following intracerebroventricular injection…”
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Central nervous system depressant effects of N super(3)-substituted derivatives of deoxyuridine in mice by Kimura, T, Kuze, J, Teraoka, S, Watanabe, K, Tateoka, Y, Kondo, S, Ho, K, Yamamoto, I

“…N super(3)-Substituted derivatives of deoxyuridine (1) were synthesized and their pharmacological effects were evaluated by intracerebroventricular (i.c.v.)…”
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N3-Phenacyluridine, a novel hypnotic compound, interacts with the benzodiazepine receptor by Kimura, Toshiyuki, Kuze, Jiro, Watanabe, Kazuhito, Kondo, Shigemi, Ho, Ing Kang, Yamamoto, Ikuo

“…N 3-Phenacyluridine (3-phenacyl-1-β- d-ribofuranosyluracil) has potent sedative and hypnotic activities following intracerebroventricular injection in mice. To…”
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The potent depressant effects of N super(3)-phenacyluridine in mice by Yamamoto, I, Kuze, J, Kimura, T, Watanabe, K, Kondo, S, Ho, I K

“…The hypnotic activity of N super(3)-phenacyluridine in 2.0 mu mol/mouse by intracerebroventricular (i.c.v.) injection was 20 times stronger than that of known…”
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Central Nervous System Depressant Effects of N3-Substituted Derivatives of Deoxyuridine in Mice by KIMURA, Toshiyuki, KUZE, Jiro, TERAOKA, Seisaku, WATANABE, Kazuhito, TATEOKA, Yuji, KONDO, Shigemi, HO, IngKang, YAMAMOTO, Ikuo

“…N3-Substituted derivatives of deoxyuridine (1) were synthesized and their pharmacological effects were evaluated by intracerebroventricular (i.c.v.) injection…”
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The Potent Depressant Effects of N3-Phenacyluridine in Mice by YAMAMOTO, Ikuo, KUZE, Jiro, KIMURA, Toshiyuki, WATANABE, Kazuhito, KONDO, Shigemi, HO, IngKang

“…The hypnotic activity of N3-phenacyluridine in 2.0μmol/mouse by intracerebroventricular (i.c.v.) injection was 20 times stronger than that of known…”
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The milking routine and its role in mastitis control programs by Kuze, J. (Universidad Austral de Chile, Valdivia (Chile). Inst. de Microbiologia)

“…Durante el proceso de la ordeña existe un alto riesgo de infección intramamaria y de transmisión de los agentes causantes de mastitis, especialmente, de los…”
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