Search Results - "Kuze, J"
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Evaluation of animal models for intestinal first-pass metabolism of drug candidates to be metabolized by CYP3A enzymes via in vivo and in vitro oxidation of midazolam and triazolam
Published in Xenobiotica (01-07-2013)“…Abstract 1. To search an appropriate evaluation methodology for the intestinal first-pass metabolism of new drug candidates, grapefruit juice (GFJ)- and…”
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Separate evaluation of intestinal and hepatic metabolism of three benzodiazepines in rats with cannulated portal and jugular veins: comparison with the profile in non-cannulated mice
Published in Xenobiotica (01-11-2009)“…Pharmacokinetic analyses of three kinds of benzodiazepines-midazolam (MDZ), triazolam (TRZ) and alprezolam (APZ)-were performed in rats with cannulated portal…”
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Subjective evaluation of visual fatigue caused by motion images
Published in Displays (01-03-2008)“…A questionnaire was developed to subjectively assess visual fatigue caused by viewing various types of motion images. The questionnaire was evaluated using…”
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FACTORS RELATED TO MENTAL HEALTH OF ELDER FAMILY CAREGIVERS IN DEMENTIA CARE
Published in Innovation in aging (01-07-2017)“…In dementia care, elder caregivers increase recently and it’s necessary to consider support according to the age of the caregivers. In this study, the degree…”
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Subjective evaluation of visual fatigue caused by motion images: Health and safety aspects of visual displays
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Binocular Rivalry Alternation Rate Declines with Age
Published in Perceptual and motor skills (01-10-2003)“…The effect of aging on the time of spontaneous perceptual alternation in binocular rivalry was examined in 59 subjects. An earlier study reported the change of…”
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Sedative and hypnotic activities of pyrimidine nucleoside derivatives
Published in Nucleic acids symposium series (1979) (1993)“…N3-Substituted pyrimidine nucleoside and their related compounds were synthesized. The central nervous system (CNS) depressant effect of the compounds such as…”
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The nucleoside derivatives possessing sedative and hypnotic effects
Published in Nucleic acids symposium series (1979) (1991)“…N3-Substituted oxopyrimidines and their related compounds were synthesized. The central nervous system (CNS) depressant activities of the compounds such as…”
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QTL analysis for plant and grain characters of Sake-brewing rice using a doubled haploid population
Published in Breeding Science (01-01-2002)“…Rice (Oryza sativa L.) varieties used for brewing sake are commonly characterized by traits such as large grain size with white-core (an opaque structure…”
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N super(3)-phenacyluridine: A novel hypnotic compound, interacts with the benzodiazepine receptor
Published in European journal of pharmacology (01-09-1996)“…N super(3)-Phenacyluridine (3-phenacyl-1- beta -D-ribofuranosyluracil) has potent sedative and hypnotic activities following intracerebroventricular injection…”
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Central nervous system depressant effects of N super(3)-substituted derivatives of deoxyuridine in mice
Published in Biological & pharmaceutical bulletin (01-01-1996)“…N super(3)-Substituted derivatives of deoxyuridine (1) were synthesized and their pharmacological effects were evaluated by intracerebroventricular (i.c.v.)…”
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N3-Phenacyluridine, a novel hypnotic compound, interacts with the benzodiazepine receptor
Published in European journal of pharmacology (12-09-1996)“…N 3-Phenacyluridine (3-phenacyl-1-β- d-ribofuranosyluracil) has potent sedative and hypnotic activities following intracerebroventricular injection in mice. To…”
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13
The potent depressant effects of N super(3)-phenacyluridine in mice
Published in Biological & pharmaceutical bulletin (01-01-1994)“…The hypnotic activity of N super(3)-phenacyluridine in 2.0 mu mol/mouse by intracerebroventricular (i.c.v.) injection was 20 times stronger than that of known…”
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Central Nervous System Depressant Effects of N3-Substituted Derivatives of Deoxyuridine in Mice
Published in Biological & pharmaceutical bulletin (01-01-1996)“…N3-Substituted derivatives of deoxyuridine (1) were synthesized and their pharmacological effects were evaluated by intracerebroventricular (i.c.v.) injection…”
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The Potent Depressant Effects of N3-Phenacyluridine in Mice
Published in Biological & pharmaceutical bulletin (1994)“…The hypnotic activity of N3-phenacyluridine in 2.0μmol/mouse by intracerebroventricular (i.c.v.) injection was 20 times stronger than that of known…”
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The milking routine and its role in mastitis control programs
Published in Archivos de medicina veterinaria (1998)“…Durante el proceso de la ordeña existe un alto riesgo de infección intramamaria y de transmisión de los agentes causantes de mastitis, especialmente, de los…”
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