Search Results - "Kuwahara‐Ota, Saeko"

Lenalidomide and pomalidomide potently interfere with induction of myeloid‐derived suppressor cells in multiple myeloma by Kuwahara‐Ota, Saeko, Shimura, Yuji, Steinebach, Christian, Isa, Reiko, Yamaguchi, Junko, Nishiyama, Daichi, Fujibayashi, Yuto, Takimoto‐Shimomura, Tomoko, Mizuno, Yoshimi, Matsumura‐Kimoto, Yayoi, Tsukamoto, Taku, Chinen, Yoshiaki, Kobayashi, Tsutomu, Horiike, Shigeo, Taniwaki, Masafumi, Gütschow, Michael, Kuroda, Junya

“…Summary An increase in immunosuppressive myeloid‐derived suppressor cells (MDSCs) is associated with disease progression and treatment resistance in multiple…”
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Tumour‐derived exosomes promote the induction of monocytic myeloid‐derived suppressor cells from peripheral blood mononuclear cells by delivering miR ‐106a‐5p and miR ‐146a‐5p in multiple myeloma by Mizuhara, Kentaro, Shimura, Yuji, Tsukamoto, Taku, Kanai, Akinori, Kuwahara‐Ota, Saeko, Yamaguchi, Junko, Muramatsu, Ayako, Okamoto, Haruya, Taminishi‐Katsuragawa, Yoko, Kawaji‐Kanayama, Yuka, Isa, Reiko, Mizutani, Shinsuke, Inaba, Toshiya, Kuroda, Junya

“…The shift of the tumour immune microenvironment to a suppressive state promotes not only the development and progression of the disease in multiple myeloma…”
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Toward further simplification of elotuzumab therapy by subcutaneous administration by Shimura, Yuji, Tsukamoto, Taku, Yamaguchi, Junko, Kuwahara-Ota, Saeko, Isa, Reiko, Nishiyama, Daichi, Kobayashi, Tsutomu, Horiike, Shigeo, Suzuki, Atsushi, Kuroda, Junya

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EWSR1 overexpression is a pro-oncogenic event in multiple myeloma by Nishiyama, Daichi, Chinen, Yoshiaki, Isa, Reiko, Fujibayashi, Yuto, Kuwahara-Ota, Saeko, Yamaguchi, Junko, Takimoto-Shimomura, Tomoko, Matsumura-Kimoto, Yayoi, Tsukamoto, Taku, Shimura, Yuji, Kobayashi, Tsutomu, Horiike, Shigeo, Taniwaki, Masafumi, Handa, Hiroshi, Kuroda, Junya

“…Multiple myeloma (MM) is cytogenetically, genetically and molecularly heterogenous even among subclones in one patient, therefore, it is essential to identify…”
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Serine‐227 in the N‐terminal kinase domain of RSK2 is a potential therapeutic target for mantle cell lymphoma by Matsumura‐Kimoto, Yayoi, Tsukamoto, Taku, Shimura, Yuji, Chinen, Yoshiaki, Tanba, Kazuna, Kuwahara‐Ota, Saeko, Fujibayashi, Yuto, Nishiyama, Daichi, Isa, Reiko, Yamaguchi, Junko, Kawaji‐Kanayama, Yuka, Kobayashi, Tsutomu, Horiike, Shigeo, Taniwaki, Masafumi, Kuroda, Junya

“…RSK2 is a serine/threonine kinase downstream signaling mediator in the RAS/ERK signaling pathway and may be a therapeutic target in mantle cell lymphoma (MCL),…”
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A novel method of amplified fluorescent in situ hybridization for detection of chromosomal microdeletions in B cell lymphoma by Mizuno, Yoshimi, Chinen, Yoshiaki, Tsukamoto, Taku, Takimoto-Shimomura, Tomoko, Matsumura-Kimoto, Yayoi, Fujibayashi, Yuto, Kuwahara-Ota, Saeko, Fujino, Takahiro, Nishiyama, Daichi, Shimura, Yuji, Kobayashi, Tsutomu, Horiike, Shigeo, Taniwaki, Masafumi, Kuroda, Junya

“…Chromosomal microdeletions frequently cause loss of prognostically relevant tumor suppressor genes in hematologic malignancies; however, detection of minute…”
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Chromosomal abnormality variation detected by G‐banding is associated with prognosis of diffuse large B‐cell lymphoma treated by R‐CHOP‐based therapy by Mizuno, Yoshimi, Tsukamoto, Taku, Kawata, Eri, Uoshima, Nobuhiko, Uchiyama, Hitoji, Yokota, Isao, Maegawa, Saori, Takimoto, Tomoko, Tanba, Kazuna, Matsumura‐Kimoto, Yayoi, Kuwahara‐Ota, Saeko, Fujibayashi, Yuto, Yamamoto‐Sugitani, Mio, Chinen, Yoshiaki, Shimura, Yuji, Horiike, Shigeo, Taniwaki, Masafumi, Kobayashi, Tsutomu, Kuroda, Junya

“…Diffuse large B‐cell lymphoma (DLBCL), which is the most prevalent disease subtype of non‐Hodgkin lymphoma, is highly heterogeneous in terms of cytogenetic and…”
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Clinical impacts of severe thrombocytopenia in the first cycle of azacitidine monotherapy and cytogenetics in patients with myelodysplastic syndrome: The Kyoto Conditional Survival Scoring System by Inoue, Yu, Okamoto, Haruya, Miyashita, Akihiro, Kawaji-Kanayama, Yuka, Chinen, Shotaro, Fujino, Takahiro, Tsukamoto, Taku, Shimura, Yuji, Mizutani, Shinsuke, Kaneko, Hiroto, Kuwahara-Ota, Saeko, Fuchida, Shin-Ichi, Nishiyama, Daichi, Hirakawa, Koichi, Uchiyama, Hitoji, Uoshima, Nobuhiko, Kawata, Eri, Kuroda, Junya

“…Azacitidine (AZA) has been one of the standard treatments for transplantation-ineligible patients with myelodysplastic syndrome (MDS); however, hematological…”
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Epstein-Barr virus-associated lymphoproliferative disease during imatinib mesylate treatment for chronic myeloid leukemia by Yamaguchi, Junko, Fujino, Takahiro, Isa, Reiko, Nishiyama, Daichi, Kuwahara-Ota, Saeko, Kawaji, Yuka, Tsukamoto, Taku, Chinen, Yoshiaki, Shimura, Yuji, Kobayashi, Tsutomu, Horiike, Shigeo, Kohno, Kei, Nakamura, Shigeo, Kuroda, Junya

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Aberrant BUB1 Overexpression Promotes Mitotic Segregation Errors and Chromosomal Instability in Multiple Myeloma by Fujibayashi, Yuto, Isa, Reiko, Nishiyama, Daichi, Sakamoto-Inada, Natsumi, Kawasumi, Norichika, Yamaguchi, Junko, Kuwahara-Ota, Saeko, Matsumura-Kimoto, Yayoi, Tsukamoto, Taku, Chinen, Yoshiaki, Shimura, Yuji, Kobayashi, Tsutomu, Horiike, Shigeo, Taniwaki, Masafumi, Handa, Hiroshi, Kuroda, Junya

“…Chromosome instability (CIN), the hallmarks of cancer, reflects ongoing chromosomal changes caused by chromosome segregation errors and results in whole…”
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Mir-106a-5p and Mir-146a-5p Delivered By Tumor-Derived Exosomes Promote the Induction of Myeloid-Derived Suppressor Cells from Normal Peripheral Blood Mononuclear Cells in Multiple Myeloma by Mizuhara, Kentaro, Shimura, Yuji, Tsukamoto, Taku, Kanai, Akinori, Kuwahara-Ota, Saeko, Yamaguchi, Junko, Muramatsu, Ayako, Okamoto, Haruya, Katsuragawa-Taminishi, Yoko, Kawaji-Kanayama, Yuka, Isa, Reiko, Mizutani, Shinsuke, Inaba, Toshiya, Kuroda, Junya

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Tumor-specific transcript variants of cyclin D1 in mantle cell lymphoma and multiple myeloma with chromosome 11q13 abnormalities by Chinen, Yoshiaki, Tsukamoto, Taku, Maegawa-Matsui, Saori, Matsumura-Kimoto, Yayoi, Takimoto-Shimomura, Tomoko, Tanba, Kazuna, Mizuno, Yoshimi, Fujibayashi, Yuto, Kuwahara-Ota, Saeko, Shimura, Yuji, Kobayashi, Tsutomu, Horiike, Shigeo, Taniwaki, Masafumi, Kuroda, Junya

“…•Mantle cell lymphoma and multiple myeloma with 11q13 abnormalities express Cyclin D1 transcript variants with longer 5′-UTRs.•Cyclin D1 transcript variants…”
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Real-world practice-based prognostic model for higher-risk myelodysplastic syndromes treated with azacitidine monotherapy: The Kyoto prognostic scoring system by Okamoto, Haruya, Inoue, Yu, Miyashita, Akihiro, Kawaji-Kanayama, Yuka, Chinen, Shotaro, Fujino, Takahiro, Tsukamoto, Taku, Shimura, Yuji, Mizutani, Shinsuke, Kaneko, Hiroto, Kuwahara-Ota, Saeko, Fuchida, Shin-ichi, Nishiyama, Daichi, Hirakawa, Koichi, Uchiyama, Hitoji, Uoshima, Nobuhiko, Kawata, Eri, Kuroda, Junya

“…The prognostic impact of patient-related factors, including age, nutritional parameters, and inflammation status, in higher-risk myelodysplastic syndromes…”
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BRD4-Regulated Molecular Targets in Mantle Cell Lymphoma: Insights into Targeted Therapeutic Approach by TSUKAMOTO, TAKU, NAKAHATA, SHINGO, SATO, RYUICHI, KANAI, AKINORI, NAKANO, MASAKAZU, CHINEN, YOSHIAKI, MAEGAWA-MATSUI, SAORI, MATSUMURA-KIMOTO, YAYOI, TAKIMOTO-SHIMOMURA, TOMOKO, MIZUNO, YOSHIMI, KUWAHARA-OTA, SAEKO, KAWAJI, YUKA, TANIWAKI, MASAFUMI, INABA, TOSHIYA, TASHIRO, KEI, MORISHITA, KAZUHIRO, KURODA, JUNYA

“…Background: Since bromodomain-containing protein 4 (BRD4) facilitates the transcription of genes important for neoplastic cells in a cancer-type specific…”
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Prediction of delayed platelet engraftment after autologous stem cell transplantation for B-cell non-Hodgkin lymphoma by Yamaguchi, Junko, Chinen, Yoshiaki, Takimoto-Shimomura, Tomoko, Nagata, Hiroaki, Muramatsu, Ayako, Kuriyama, Kodai, Ohshiro, Muneo, Hirakawa, Yoshiko, Iwai, Toshiki, Uchiyama, Hitoji, Uoshima, Nobuhiko, Kaneko, Hiroto, Nakao, Mitsushige, Tsukamoto, Taku, Shimura, Yuji, Kobayashi, Tsutomu, Horiike, Shigeo, Yokota, Isao, Kuroda, Junya

“…Delayed platelet engraftment (DPE) is occasionally observed despite prompt neutrophil engraftment after autologous peripheral blood stem cell transplantation…”
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Tuberculosis Peritonitis During Treatment of Polycythemia Vera with Ruxolitinib by Sakiyama, Emiko, Chinen, Yoshiaki, Tsukamoto, Taku, Takimoto-Shimomura, Tomoko, Kuwahara-Ota, Saeko, Matsumura-Kimoto, Yayoi, Shimura, Yuji, Kobayashi, Tsutomu, Horiike, Shigeo, Kuroda, Junya

“…Ruxolitinib is a selective JAK1/2 inhibitor that is widely used for the treatment of myeloproliferative neoplasms (MPNs), including myelofibrosis and…”
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Phosphoinositide-dependent protein kinase 1 is a potential novel therapeutic target in mantle cell lymphoma by Maegawa, Saori, Chinen, Yoshiaki, Shimura, Yuji, Tanba, Kazuna, Takimoto, Tomoko, Mizuno, Yoshimi, Matsumura-Kimoto, Yayoi, Kuwahara-Ota, Saeko, Tsukamoto, Taku, Kobayashi, Tsutomu, Horiike, Shigeo, Taniwaki, Masafumi, Kuroda, Junya

“…•3-Phosphoinositide-dependent protein kinase 1 (PDPK1) is found to be constitutively activated in various types of patient-derived B-cell non-Hodgkin lymphoma…”
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Human herpesvirus-6 pneumonitis in a patient with follicular lymphoma following immunochemotherapy with rituximab by Kuwahara-Ota, Saeko, Chinen, Yoshiaki, Mizuno, Yoshimi, Takimoto-Shimomura, Tomoko, Matsumura-Kimoto, Yayoi, Tanba, Kazuna, Tsukamoto, Taku, Mizutani, Shinsuke, Shimura, Yuji, Kobayashi, Tsutomu, Horiike, Shigeo, Kuroda, Junya

“…Primary infection with human herpesvirus-6 (HHV-6) commonly occurs at an early age in children, most often at 3 years of age, and is associated with childhood…”
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Tuberculosis Peritonitis During Treatment of Polycythemia Vera with Ruxolitinib by Sakiyama, Emiko, Chinen, Yoshiaki, Tsukamoto, Taku, Takimoto-Shimomura, Tomoko, Kuwahara-Ota, Saeko, Matsumura-Kimoto, Yayoi, Shimura, Yuji, Kobayashi, Tsutomu, Horiike, Shigeo, Kuroda, Junya

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Human herpesvirus-6 pneumonitis in a patient with follicular lymphoma following immunochemotherapy with rituximab by Kuwahara-Ota, Saeko, Chinen, Yoshiaki, Mizuno, Yoshimi, Takimoto-Shimomura, Tomoko, Matsumura-Kimoto, Yayoi, Tanba, Kazuna, Tsukamoto, Taku, Mizutani, Shinsuke, Shimura, Yuji, Kobayashi, Tsutomu, Horiike, Shigeo, Kuroda, Junya

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