Search Results - "Kuut, Gunnar"
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Tumor necrosis factor is a necroptosis-associated alarmin
Published in Frontiers in immunology (12-12-2022)“…Necroptosis is a form of regulated cell death that can occur downstream of several immune pathways. While previous studies have shown that dysregulated…”
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Genome Replication Is Associated With Release of Immunogenic DNA Waste
Published in Frontiers in immunology (11-05-2022)“…Innate DNA sensors detect foreign and endogenous DNA to induce responses to infection and cellular stress or damage. Inappropriate activation by self-DNA…”
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Potential of polyE-323 coated capillaries for capillary electrophoresis of lipids
Published in Journal of Chromatography A (22-11-2013)“…•Study of the resistance of polyamine-based capillary coating to organic solvents.•Development of organic solution based BGE for lipid analysis in polyE-323…”
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STING agonism turns human T cells into interferon‐producing cells but impedes their functionality
Published in EMBO reports (06-03-2023)“…The cGAS‐STING (cyclic GMP‐AMP synthase‐stimulator of interferon genes) axis is the predominant DNA sensing system in cells of the innate immune system…”
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Sting Activation Improves T-Cell Engaging Immunotherapy of Acute Myeloid Leukemia
Published in Blood (02-11-2023)“…Background: Despite emerging therapeutic options for Acute myeloid leukemia (AML) patients, for the majority of relapsed/refractory patients the outcome…”
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C-tag TNF: a reporter system to study TNF shedding
Published in The Journal of biological chemistry (25-12-2020)“…TNF is a highly pro-inflammatory cytokine that contributes not only to the regulation of immune responses but also to the development of severe inflammatory…”
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Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation
Published in Nature (London) (15-09-2022)“…Bacterial cell wall components provide various unique molecular structures that are detected by pattern recognition receptors (PRRs) of the innate immune…”
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C-tag TNF: a reporter system to study TNF shedding
Published in The Journal of biological chemistry (25-12-2020)“…TNF is a highly pro-inflammatory cytokine that contributes not only to the regulation of immune responses but also to the development of severe inflammatory…”
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