Search Results - "Kuttiyara, Jason"

A tissue-intrinsic IL-33/EGF circuit promotes epithelial regeneration after intestinal injury by Calafiore, Marco, Fu, Ya-Yuan, Vinci, Paola, Arnhold, Viktor, Chang, Winston Y., Jansen, Suze A., Egorova, Anastasiya, Takashima, Shuichiro, Kuttiyara, Jason, Ito, Takahiro, Serody, Jonathan, Nakae, Susumu, Turnquist, Heth, van Es, Johan, Clevers, Hans, Lindemans, Caroline A., Blazar, Bruce R., Hanash, Alan M.

“…Intestinal stem cells (ISCs) maintain the epithelial lining of the intestines, but mechanisms regulating ISCs and their niche after damage remain poorly…”
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T Cell Recruitment to the Intestinal Stem Cell Compartment Drives Immune-Mediated Intestinal Damage after Allogeneic Transplantation by Fu, Ya-Yuan, Egorova, Anastasiya, Sobieski, Catherine, Kuttiyara, Jason, Calafiore, Marco, Takashima, Shuichiro, Clevers, Hans, Hanash, Alan M.

“…The key sites within the gastrointestinal (GI) tract where T cells mediate effector responses and the impact of these responses on intestinal stem cells (ISCs)…”
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Immunosuppressive therapy of immune-mediated GI damage may impair epithelial regeneration by Arnhold, Viktor, Takashima, Shuichiro, Vinci, Paola, Kuttiyara, Jason, Egorova, Anastasiya, Calafiore, Marco, Hanash, Alan

“…Glucocorticoids (GC) are a standard therapy of immune-mediated gastrointestinal (GI) damage. However, there is little understanding of the effects that GC use…”
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Attenuation of Graft-Versus-Host-Disease Via Genetic or Pharmacologic Inhibition of the RNA Splicing Factor RBM39 by Bourcier, Jessie, Hogg, Simon J., Erickson, Caroline, Singer, Michael E, Tittley, Steven, Ito, Takahiro, Egorova, Anastasiya, Kuttiyara, Jason, Hanash, Alan M., Abdel-Wahab, Omar, Lu, Sydney X.

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Donor-Derived Amphiregulin Drives CD4+ T Cell Expansion and Promotes Tissue Pathology after Experimental Allogeneic BMT by Ito, Takahiro, Takashima, Shuichiro, Calafiore, Marco, Fu, Ya-Yuan, Egorova, Anastasiya, Kuttiyara, Jason, Chang, Winston, Vinci, Paola, Arnhold, Viktor, Zaiss, Dietmar, Hanash, Alan M.

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Immune-Mediated Reprogramming of Intestinal Stem Cells Drives STAT1-Dependent Myc Expression and Epithelial Regeneration in GI-Gvhd by Takashima, Shuichiro, Sharma, Roshan, Egorova, Anastasiya, Kuttiyara, Jason, Ito, Takahiro, Chang, Winston, Jansen, Suze A, Liu, Chen, Lindemans, Caroline, Mazutis, Linas, Robine, Nicolas, Hanash, Alan M

“…Crypt apoptosis and regeneration are characteristic findings in GI-GVHD. Intestinal stem cells (ISCs) are critical for maintaining the intestinal epithelium,…”
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Graft vs. host disease leads to elimination of tissue-resident innate lymphoid cells following experimental and clinical allogeneic transplantation by Vinci, Paola, Garcia-Martinez, Elena, O’Connor, Margaret H., Egorova, Anastasiya, Kuttiyara, Jason, Arnhold, Viktor, Ponce, Doris M., Hanash, Alan M.

“…Innate lymphoid cells (ILCs) are associated with protective mucosal responses after allogeneic bone marrow transplantation (allo-BMT). However, the specific in…”
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Corticosteroids impair epithelial regeneration in immune-mediated intestinal damage by Arnhold, Viktor, Chang, Winston Y, Jansen, Suze A, Thangavelu, Govindarajan, Calafiore, Marco, Vinci, Paola, Fu, Ya-Yuan, Ito, Takahiro, Takashima, Shuichiro, Egorova, Anastasiya, Kuttiyara, Jason, Perlstein, Adam, van Hoesel, Marliek, Liu, Chen, Blazar, Bruce R, Lindemans, Caroline A, Hanash, Alan M

“…Corticosteroid treatment (CST) failure is associated with poor outcomes for patients with gastrointestinal graft-versus-host disease (GI GVHD). CST is intended…”
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Graft Versus Host Disease Leads to Elimination of Tissue-Resident Innate Lymphoid Cells Following Experimental and Clinical Allogeneic Transplantation by Vinci, Paola, Garcia-Martinez, Elena, O'Connor, Margaret H., Egorova, Anastasiya, Kuttiyara, Jason, Arnhold, Viktor, Ponce, Doris M, Hanash, Alan M.

“…A potential role for endogenous innate lymphoid cells (ILCs) in prevention of gastrointestinal (GI) GVHD has recently been described in murine and clinical…”
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38 - IL-22 Producing Innate Lymphocytes Traffic to the Intestinal Stem Cell Compartment after Conditioning-Related Radiation Injury by Fu, Ya-Yuan, Egorova, Anastasiya, Kuttiyara, Jason, Hanash, Alan M.

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IL-22 Producing Innate Lymphocytes Traffic to the Intestinal Stem Cell Compartment after Conditioning-Related Radiation Injury by Fu, Ya-Yuan, Egorova, Anastasiya, Kuttiyara, Jason, Hanash, Alan M.

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IL-33 Induces Paneth Cell Production of EGF and Soluble ST2, Regulating Epithelial Regeneration after Intestinal Injury by Calafiore, Marco, Fu, YA-Yuan, Vinci, Paola, Arnhold, Viktor, Chang, Winston, Jansen, Suze, Egorova, Anastasiya, Takashima, Shuichiro, Kuttiyara, Jason, Ito, Takahiro, Serody, Jonathan, Nakae, Susumu, Turnquist, Heth, van Es, Johan, Clevers, Hans, Lindemans, Caroline A., Blazar, Bruce R, Hanash, Alan M.

“…Crypt base intestinal stem cells (ISCs) maintain the epithelial lining of the intestines, but their frequencies are reduced in experimental models of graft vs…”
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Corticosteroid Treatment Impairs Epithelial Regeneration, Limiting Intestinal Recovery in Experimental Graft Vs Host Disease by Arnhold, Viktor, Jansen, Suze A, Chang, Winston, Thangavelu, Govindarajan, Vinci, Paola, Takashima, Shuichiro, Egorova, Anastasiya, Kuttiyara, Jason, van Hoesel, Marliek, Liu, Chen, Calafiore, Marco, Blazar, Bruce R., Lindemans, Caroline, Hanash, Alan M

“…Corticosteroids (CS) represent first-line treatment for gastrointestinal graft vs host disease (GI GVHD), and CS failure is associated with severe morbidity…”
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Tracking Immune Reconstitution in the Bone Marrow Following Allogeneic Hematopoietic Transplantation in Humans Reveals Early Dominance of Innate Lymphoid Populations by DeWolf, Susan, Kuttiyara, Jason, Vinci, Paola, Slingerland, John, Marcello, Leeann T., Giardina, Paul A., Donohoe, William, Lin, Richard J., Papadopoulos, Esperanza B., Gyurkocza, Boglarka, Shaffer, Brian C., Tallman, Martin S., Giralt, Sergio A., Politikos, Ioannis, Barker, Juliet N., Tamari, Roni, Cho, Christina, Perales, Miguel-Angel, van den Brink, Marcel R.M., Hanash, Alan M.

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4 - Paneth Cell Niche Function Is Dispensable in Gvhd by Arnhold, Viktor, Chang, Winston, Fu, Ya-Yuan, Vinci, Paola, Takashima, Shuichiro, Ito, Takahiro, Egorova, Anastasiya, Kuttiyara, Jason, Liu, Chen, Calafiore, Marco, Hanash, Alan M.

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Paneth Cell Niche Function Is Dispensable in Gvhd by Arnhold, Viktor, Chang, Winston, Fu, Ya-Yuan, Vinci, Paola, Takashima, Shuichiro, Ito, Takahiro, Egorova, Anastasiya, Kuttiyara, Jason, Liu, Chen, Calafiore, Marco, Hanash, Alan M.

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72 - The Amphiregulin/EGFR Axis Regulates Donor T Cell Expansion and Contributes to Intestinal Gvhd Pathology after Allogeneic Bone Marrow Transplantation by Ito, Takahiro, Takashima, Shuichiro, Calafiore, Marco, Fu, Ya-Yuan, Egorova, Anastasiya, Kuttiyara, Jason, Chang, Winston, Vinci, Paola, Arnhold, Viktor, Zaiss, Dietmar, Hanash, Alan M.

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The Amphiregulin/EGFR Axis Regulates Donor T Cell Expansion and Contributes to Intestinal Gvhd Pathology after Allogeneic Bone Marrow Transplantation by Ito, Takahiro, Takashima, Shuichiro, Calafiore, Marco, Fu, Ya-Yuan, Egorova, Anastasiya, Kuttiyara, Jason, Chang, Winston, Vinci, Paola, Arnhold, Viktor, Zaiss, Dietmar, Hanash, Alan M.

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368 - IL-22 Treatment Overcomes Corticosteroid-Mediated Suppression of Epithelial Regeneration and Exacerbation of Gvhd-Associated GI Damage by Arnhold, Viktor, Jansen, Suze A., Chang, Winston, Thangavelu, Govindarajan, Vinci, Paola, Takashima, Shuichiro, Egorova, Anastasiya, Kuttiyara, Jason, Liu, Chen, Calafiore, Marco, Blazar, Bruce R., Lindemans, Caroline A., Hanash, Alan M.

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IL-22 Treatment Overcomes Corticosteroid-Mediated Suppression of Epithelial Regeneration and Exacerbation of Gvhd-Associated GI Damage by Arnhold, Viktor, Jansen, Suze A., Chang, Winston, Thangavelu, Govindarajan, Vinci, Paola, Takashima, Shuichiro, Egorova, Anastasiya, Kuttiyara, Jason, Liu, Chen, Calafiore, Marco, Blazar, Bruce R., Lindemans, Caroline A., Hanash, Alan M.

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