Search Results - "Kutluer, Meltem"
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New In Vitro Cellular Model for Molecular Studies of Retinitis Pigmentosa
Published in International journal of molecular sciences (16-06-2021)“…Retinitis pigmentosa (RP) is an inherited form of retinal degeneration characterized by primary rod photoreceptor cell death followed by cone loss. Mutations…”
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Journal Article -
2
Targeting molecular pathways for the treatment of inherited retinal degeneration
Published in Neural regeneration research (01-10-2020)“…Inherited retinal degeneration is a major cause of incurable blindness characterized by loss of retinal photoreceptor cells. Inherited retinal degeneration is…”
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Journal Article -
3
Novel 2′-alkoxymethyl substituted klavuzon derivatives as inhibitors of Topo I and CRM1
Published in Bioorganic chemistry (01-10-2020)“…Nine novel 2′-alkoxymethylsubstituted klavuzon derivatives have been synthesized and tested for their antiproliferative activities against healthy and…”
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Journal Article -
4
CRM1 inhibitory and antiproliferative activities of novel 4′-alkyl substituted klavuzon derivatives
Published in Bioorganic & medicinal chemistry (15-08-2017)“…[Display omitted] •Syntheses of nine novel 4′-alkyl substituted klavuzon derivatives were performed.•Roles of substituents over potency and selectivity…”
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Journal Article -
5
Investigation of the Effect of 4'-alkylıklavuzon Derivatives on Nucleotide Synthesis and Nucleocytoplasmic Transport
Published 01-01-2016“…In anti-cancer agent development studies one of the most significant issue is to get an agent that specifically targets cancer cells without any effects on…”
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Dissertation