Search Results - "Kutkat, Omnia"

Robust antiviral activity of commonly prescribed antidepressants against emerging coronaviruses: in vitro and in silico drug repurposing studies by Kutkat, Omnia, Moatasim, Yassmin, Al‐Karmalawy, Ahmed A., Abulkhair, Hamada S., Gomaa, Mokhtar R., El-Taweel, Ahmed N., Abo Shama, Noura M., GabAllah, Mohamed, Mahmoud, Dina B., Kayali, Ghazi, Ali, Mohamed A., Kandeil, Ahmed, Mostafa, Ahmed

“…During the current coronavirus disease 2019 (COVID-19) pandemic, symptoms of depression are commonly documented among both symptomatic and asymptomatic…”
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EGYVIR: An immunomodulatory herbal extract with potent antiviral activity against SARS-CoV-2 by Roshdy, Wael H, Rashed, Helmy A, Kandeil, Ahmed, Mostafa, Ahmed, Moatasim, Yassmin, Kutkat, Omnia, Abo Shama, Noura M, Gomaa, Mokhtar R, El-Sayed, Ibrahim H, El Guindy, Nancy M, Naguib, Amal, Kayali, Ghazi, Ali, Mohamed A

“…Due to the challenges for developing vaccines in devastating pandemic situations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), developing…”
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FDA-Approved Drugs with Potent In Vitro Antiviral Activity against Severe Acute Respiratory Syndrome Coronavirus 2 by Mostafa, Ahmed, Kandeil, Ahmed, A M M Elshaier, Yaseen, Kutkat, Omnia, Moatasim, Yassmin, Rashad, Adel A, Shehata, Mahmoud, Gomaa, Mokhtar R, Mahrous, Noura, Mahmoud, Sara H, GabAllah, Mohamed, Abbas, Hisham, Taweel, Ahmed El, Kayed, Ahmed E, Kamel, Mina Nabil, Sayes, Mohamed El, Mahmoud, Dina B, El-Shesheny, Rabeh, Kayali, Ghazi, Ali, Mohamed A

“…(1) Background: Drug repositioning is an unconventional drug discovery approach to explore new therapeutic benefits of existing drugs. Currently, it emerges as…”
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Anticoagulants as Potential SARS-CoV-2 Mpro Inhibitors for COVID-19 Patients: In Vitro, Molecular Docking, Molecular Dynamics, DFT, and SAR Studies by Abo Elmaaty, Ayman, Eldehna, Wagdy, Khattab, Muhammad, Kutkat, Omnia, Alnajjar, Radwan, El-Taweel, Ahmed, Al-Rashood, Sara, Abourehab, Mohammed, Binjubair, Faizah, Saleh, Mohamed, Belal, Amany, Al-Karmalawy, Ahmed

“…In this article, 34 anticoagulant drugs were screened in silico against the main protease (Mpro) of SARS-CoV-2 using molecular docking tools. Idraparinux,…”
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Bioactive Polyphenolic Compounds Showing Strong Antiviral Activities against Severe Acute Respiratory Syndrome Coronavirus 2 by Kandeil, Ahmed, Mostafa, Ahmed, Kutkat, Omnia, Moatasim, Yassmin, Al-Karmalawy, Ahmed A, Rashad, Adel A, Kayed, Ahmed E, Kayed, Azza E, El-Shesheny, Rabeh, Kayali, Ghazi, Ali, Mohamed A

“…Until now, there has been no direct evidence of the effectiveness of repurposed FDA-approved drugs against Severe Acute Respiratory Syndrome Coronavirus 2…”
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Eucalyptus Oils Phytochemical Composition in Correlation with Their Newly Explored Anti-SARS-CoV-2 Potential: in Vitro and in Silico Approaches by El-Shiekh, Riham A., Okba, Mona M., Mandour, Asmaa A., Kutkat, Omnia, Elshimy, Rana, Nagaty, Hany A., Ashour, Rehab M.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the latest arisen contagious respiratory pathogen related to the global outbreak of atypical…”
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Design, Synthesis and In Vitro Evaluation of Spirooxindole-Based Phenylsulfonyl Moiety as a Candidate Anti-SAR-CoV-2 and MERS-CoV-2 with the Implementation of Combination Studies by Barakat, Assem, Mostafa, Ahmed, Ali, M., Al-Majid, Abdullah Mohammed, Domingo, Luis R., Kutkat, Omnia, Moatasim, Yassmin, Zia, Komal, Ul-Haq, Zaheer, Elshaier, Yaseen A. M. M.

“…The search for an effective anti-viral to inhibit COVID-19 is a challenge for the specialized scientific research community. This work investigated the…”
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Aurasperone A Inhibits SARS CoV-2 In Vitro: An Integrated In Vitro and In Silico Study by ElNaggar, Mai H, Abdelwahab, Ghada M, Kutkat, Omnia, GabAllah, Mohamed, Ali, Mohamed A, El-Metwally, Mohamed E A, Sayed, Ahmed M, Abdelmohsen, Usama Ramadan, Khalil, Ashraf T

“…Several natural products recovered from a marine-derived were tested for their inhibitory activity against SARS CoV-2 in vitro. Aurasperone A ( ) was found to…”
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Development of spiro-3-indolin-2-one containing compounds of antiproliferative and anti-SARS-CoV-2 properties by Fawazy, Nehmedo G., Panda, Siva S., Mostafa, Ahmed, Kariuki, Benson M., Bekheit, Mohamed S., Moatasim, Yassmin, Kutkat, Omnia, Fayad, Walid, El-Manawaty, May A., Soliman, Ahmed A. F., El-Shiekh, Riham A., Srour, Aladdin M., Barghash, Reham F., Girgis, Adel S.

“…A series of 1″-(alkylsulfonyl)-dispiro[indoline-3,2′-pyrrolidine-3′,3″-piperidine]-2,4″-diones 6a‒o has been synthesized through regioselective multi-component…”
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Strong Inhibitory Activity and Action Modes of Synthetic Maslinic Acid Derivative on Highly Pathogenic Coronaviruses: COVID-19 Drug Candidate by Soltane, Raya, Chrouda, Amani, Mostafa, Ahmed, Al-Karmalawy, Ahmed A, Chouaïb, Karim, Dhahri, Abdelwaheb, Pashameah, Rami Adel, Alasiri, Ahlam, Kutkat, Omnia, Shehata, Mahmoud, Jannet, Hichem Ben, Gharbi, Jawhar, Ali, Mohamed A

“…In late December 2019, a novel coronavirus, namely severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), escaped the animal-human interface and emerged…”
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Design and statistical optimisation of emulsomal nanoparticles for improved anti-SARS-CoV-2 activity of N-(5-nitrothiazol-2-yl)-carboxamido candidates: in vitro and in silico studies by Al-Karmalawy, Ahmed A., El-Gamil, Dalia S., El-Shesheny, Rabeh, Sharaky, Marwa, Alnajjar, Radwan, Kutkat, Omnia, Moatasim, Yassmin, Elagawany, Mohamed, Al-Rashood, Sara T., Binjubair, Faizah A., Eldehna, Wagdy M., Noreddin, Ayman M., Zakaria, Mohamed Y.

“…In this article, emulsomes (EMLs) were fabricated to encapsulate the N-(5-nitrothiazol-2-yl)-carboxamido derivatives (3a-3g) in an attempt to improve their…”
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Common childhood vaccines do not elicit a cross-reactive antibody response against SARS-CoV-2 by Kandeil, Ahmed, Gomaa, Mokhtar R, El Taweel, Ahmed, Mostafa, Ahmed, Shehata, Mahmoud, Kayed, Ahmed E, Kutkat, Omnia, Moatasim, Yassmin, Mahmoud, Sara H, Kamel, Mina Nabil, Shama, Noura M Abo, El Sayes, Mohamed, El-Shesheny, Rabeh, Yassien, Mahmoud A, Webby, Richard J, Kayali, Ghazi, Ali, Mohamed A

“…Anecdotal evidence showed a negative correlation between Bacille Calmette-Guérin (BCG) vaccination and incidence of COVID-19. Incidence of the disease in…”
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Insights into Genetic Characteristics and Virological Features of Endemic Avian Influenza A (H9N2) Viruses in Egypt from 2017-2021 by El Sayes, Mohamed, Kandeil, Ahmed, Moatasim, Yassmin, El Taweel, Ahmed, Rubrum, Adam, Kutkat, Omnia, Kamel, Mina Nabil, Badra, Rebecca, Barakat, Ahmed B, McKenzie, Pamela P, El-Shesheny, Rabeh, Webby, Richard J, Kayali, Ghazi, Ali, Mohamed Ahmed

“…From 2010 to 2013, genotype I avian influenza A(H9N2) viruses of the G1-lineage were isolated from several poultry species in Egypt. In 2014, novel reassortant…”
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Highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b in wild rats in Egypt during 2023 by Kutkat, Omnia, Gomaa, Mokhtar, Moatasim, Yassmin, El Taweel, Ahmed, Kamel, Mina Nabil, El Sayes, Mohamed, GabAllah, Mohamed, Kandeil, Ahmed, McKenzie, Pamela P, Webby, Richard J, Kayali, Ghazi, Ali, Mohamed Ahmed, El-Shesheny, Rabeh

“…We detected highly pathogenic avian influenza A(H5N1) virus in wild rats collected from a rural area in Giza, Egypt, near poultry farms, markets, and backyard…”
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In Vitro and In Vivo Antiviral Studies of New Heteroannulated 1,2,3-Triazole Glycosides Targeting the Neuraminidase of Influenza A Viruses by Kutkat, Omnia, Kandeil, Ahmed, Moatasim, Yassmin, Elshaier, Yaseen A M M, El-Sayed, Wael A, Gaballah, Samir T, El Taweel, Ahmed, Kamel, Mina Nabil, El Sayes, Mohamed, Ramadan, Mohammed A, El-Shesheny, Rabeh, Abdel-Megeid, Farouk M E, Webby, Richard, Kayali, Ghazi, Ali, Mohamed A

“…There is an urgent need to develop and synthesize new anti-influenza drugs with activity against different strains, resistance to mutations, and suitability…”
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Investigating the Potential Anti-SARS-CoV-2 and Anti-MERS-CoV Activities of Yellow Necklacepod among Three Selected Medicinal Plants: Extraction, Isolation, Identification, In Vitro, Modes of Action, and Molecular Docking Studies by Abd-Alla, Howaida I, Kutkat, Omnia, Sweelam, Heba-Tollah M, Eldehna, Wagdy M, Mostafa, Marwa A, Ibrahim, Magda T, Moatasim, Yassmin, GabAllah, Mohamed, Al-Karmalawy, Ahmed A

“…The anti-MERS-CoV activities of three medicinal plants (Azadirachta indica, Artemisia judaica, and Sophora tomentosa) were evaluated. The highest viral…”
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Bio-guided chemical characterization and nano-formulation studies of selected edible volatile oils with potential antibacterial and anti-SARS-CoV-2 activities by Refaey, Mohamed S., A. A. Fayed, Marwa, Kutkat, Omnia, Moatasim, Yassmin, Sameh Tolba, Nahla, Anis, Anis, Elshorbagy, Ahmed M., Nassar, Khloud, A. M. Abouzid, Khaled, A. M. M. Elshaier, Yaseen, El-Badawy, Mohamed F.

“…[Display omitted] The recent pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has opened the door to potential threats of the…”
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Drug repurposing of pyrazolotriazine derivatives as potential anti-SARS-CoV-2 agents: in vitro and in silico studies by Oudah, Khulood H., Najm, Mazin A. A., Barghash, Reham F., Kutkat, Omnia, GabAllah, Mohamed, Albohy, Amgad, Abouzid, Khaled A. M.

“…The search for new molecules targeting SARS-CoV-2 has been a priority since 2020. The continuous evolution of new mutants increases the need for more research…”
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Middle East respiratory syndrome coronavirus infection in non-camelid domestic mammals by Kandeil, Ahmed, Gomaa, Mokhtar, Shehata, Mahmoud, El-Taweel, Ahmed, Kayed, Ahmed E., Abiadh, Awatef, Jrijer, Jamel, Moatasim, Yassmin, Kutkat, Omnia, Bagato, Ola, Mahmoud, Sara, Mostafa, Ahmed, El-Shesheny, Rabeh, Perera, Ranawaka APM, Ko, Ronald LW, Hassan, Nagla, Elsokary, Basma, Allal, Lotfi, Saad, Ahmed, Sobhy, Heba, McKenzie, Pamela P., Webby, Richard J., Peiris, Malik, Ali, Mohamed A., Kayali, Ghazi

“…Dromedary camels are natural host of the Middle East respiratory syndrome coronavirus (MERS-CoV). However, there are limited studies of MERS-CoV infection of…”
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Potent Antiviral Activity of Vitamin B12 against Severe Acute Respiratory Syndrome Coronavirus 2, Middle East Respiratory Syndrome Coronavirus, and Human Coronavirus 229E by Moatasim, Yassmin, Kutkat, Omnia, Osman, Ahmed M, Gomaa, Mokhtar R, Okda, Faten, El Sayes, Mohamed, Kamel, Mina Nabil, Gaballah, Mohamed, Mostafa, Ahmed, El-Shesheny, Rabeh, Kayali, Ghazi, Ali, Mohamed A, Kandeil, Ahmed

“…Repurposing vitamins as antiviral supporting agents is a rapid approach used to control emerging viral infections. Although there is considerable evidence…”
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