Search Results - "Kuter, Katarzyna"

Overview of General and Discriminating Markers of Differential Microglia Phenotypes by Jurga, Agnieszka M., Paleczna, Martyna, Kuter, Katarzyna Z.

“…Inflammatory processes and microglia activation accompanies most of the pathophysiological diseases in the central nervous system. It is proven that glial…”
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MUFA synthesis and stearoyl-CoA desaturase as a new pharmacological target for modulation of lipid and alpha-synuclein interaction against Parkinson's disease synucleinopathy by Kula, Joanna, Kuter, Katarzyna Z.

“…Protein pathology spreading within the nervous system, accompanies neurodegeneration and a spectrum of motor and cognitive dysfunctions. Currently available…”
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Beyond the GFAP-Astrocyte Protein Markers in the Brain by Jurga, Agnieszka M, Paleczna, Martyna, Kadluczka, Justyna, Kuter, Katarzyna Z

“…The idea of central nervous system as one-man band favoring neurons is long gone. Now we all are aware that neurons and neuroglia are team players and constant…”
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Increased Beta-Hydroxybutyrate Level Is Not Sufficient for the Neuroprotective Effect of Long-Term Ketogenic Diet in an Animal Model of Early Parkinson’s Disease. Exploration of Brain and Liver Energy Metabolism Markers by Kuter, Katarzyna Z., Olech, Łukasz, Głowacka, Urszula, Paleczna, Martyna

“…The benefits of a ketogenic diet in childhood epilepsy steered up hope for neuroprotective effects of hyperketonemia in Parkinson’s disease (PD). There are…”
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The influence of preconditioning with low dose of LPS on paraquat-induced neurotoxicity, microglia activation and expression of α-synuclein and synphilin-1 in the dopaminergic system by Kuter, Katarzyna Z, Śmiałowska, Maria, Ossowska, Krystyna

“…Prolonged inflammation, oxidative stress, and protein aggregation are important factors contributing to Parkinson's disease (PD) pathology. A known ROS…”
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Increased energetic demand supported by mitochondrial electron transfer chain and astrocyte assistance is essential to maintain the compensatory ability of the dopaminergic neurons in an animal model of early Parkinson's disease by Kuter, Katarzyna Z, Olech, Łukasz, Dencher, Norbert A

“…Partial degeneration of dopaminergic neurons in the substantia nigra (SN), induces locomotor disability in animals but with time it is spontaneously…”
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Alterations of BDNF and trkB mRNA expression in the 6-hydroxydopamine-induced model of preclinical stages of Parkinson's disease: an influence of chronic pramipexole in rats by Berghauzen-Maciejewska, Klemencja, Wardas, Jadwiga, Kosmowska, Barbara, Głowacka, Urszula, Kuter, Katarzyna, Ossowska, Krystyna

“…Our recent study has indicated that a moderate lesion of the mesostriatal and mesolimbic pathways in rats, modelling preclinical stages of Parkinson's disease,…”
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GABA-A Alpha 2/3 but Not Alpha 1 Receptor Subunit Ligand Inhibits Harmaline and Pimozide-Induced Tremor in Rats by Kosmowska, Barbara, Paleczna, Martyna, Biała, Dominika, Kadłuczka, Justyna, Wardas, Jadwiga, Witkin, Jeffrey M, Cook, James M, Sharmin, Dishary, Marcinkowska, Monika, Kuter, Katarzyna Z

“…Treatment of tremors, such as in essential tremor (ET) and Parkinson's disease (PD) is mostly ineffective. Exact tremor pathomechanisms are unknown and…”
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The role of glia in Parkinson's disease: Emerging concepts and therapeutic applications by Kuter, Katarzyna Z, Cenci, M Angela, Carta, Anna R

“…Originally believed to primarily affect neurons, Parkinson's disease (PD) has recently been recognized to also affect the functions and integrity of microglia…”
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Transcriptome analysis in a rat model of l-DOPA-induced dyskinesia by Konradi, Christine, Westin, Jenny E., Carta, Manolo, Eaton, Molly E., Kuter, Katarzyna, Dekundy, Andrzej, Lundblad, Martin, Cenci, M. Angela

“…We have examined the pattern of striatal messenger RNA expression of over 8000 genes in a rat model of levodopa ( l-DOPA)-induced dyskinesia and Parkinson…”
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Role of the metabotropic glutamate receptor subtype 1 in the Harmaline-induced tremor in rats by Kolasiewicz, Wacław, Kuter, Katarzyna, Wardas, Jadwiga, Ossowska, Krystyna

“…The present study shows that JNJ 16259685—a selective antagonist of glutamate metabotropic receptor subtype 1 (mGluR1) injected in doses of 0.16 and…”
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Partial lesion of the dopaminergic innervation of the ventral striatum induces “depressive-like” behavior of rats by Katarzyna, Kuter, Wacław, Kolasiewicz, Krystyna, Gołembiowska, Anna, Dziubina, Gert, Schulze, Klemencja, Berghauzen, Jadwiga, Wardas, Krystyna, Ossowska

“…Depression is a frequent comorbid disorder in Parkinson’s disease (PD) which may precede appearance of its motor symptoms by several years. Pathomechanisms…”
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Toxic influence of subchronic paraquat administration on dopaminergic neurons in rats by Kuter, Katarzyna, Śmiałowska, Maria, Wierońska, Joanna, Zięba, Barbara, Wardas, Jadwiga, Pietraszek, Małgorzata, Nowak, Przemysław, Biedka, Izabela, Roczniak, Wojciech, Konieczny, Jolanta, Wolfarth, Stanisław, Ossowska, Krystyna

“…Abstract Paraquat is a toxin suggested to contribute to pathogenesis of Parkinson’s disease. The aim of the present study was to examine toxic influence of…”
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Effects of adenosine A2A antagonist, KW6002 on the markers of neurodegeneration in rats chronically infused with MPP+ into the cerebral ventricle through Alzet osmotic minipumps by Jadwiga, Wardas, Katarzyna, Kuter, Wacław, Kolasiewicz, Małgorzata, Zapała, Krystyna, Gołembiowska, Christa E., Muller

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Prolonged Dysfunction of Astrocytes and Activation of Microglia Accelerate Degeneration of Dopaminergic Neurons in the Rat Substantia Nigra and Block Compensation of Early Motor Dysfunction Induced by 6-OHDA by Kuter, Katarzyna, Olech, Łukasz, Głowacka, Urszula

“…Progressive degeneration of dopaminergic neurons in the substantia nigra (SN) is the underlying cause of Parkinson’s disease (PD). The disease in early stages…”
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Astrocyte support is important for the compensatory potential of the nigrostriatal system neurons during early neurodegeneration by Kuter, Katarzyna, Olech, Łukasz, Głowacka, Urszula, Paleczna, Martyna

“…Glial pathology precedes symptoms of Parkinson's disease and multiple other neurodegenerative diseases. Prolonged impairment of astrocytic functions could…”
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Adaptation within mitochondrial oxidative phosphorylation supercomplexes and membrane viscosity during degeneration of dopaminergic neurons in an animal model of early Parkinson's disease by Kuter, Katarzyna, Kratochwil, Manuela, Berghauzen-Maciejewska, Klemencja, Głowacka, Urszula, Sugawa, Michiru D., Ossowska, Krystyna, Dencher, Norbert A.

“…In Parkinson's disease (PD) motor symptoms are not observed until loss of 70% of dopaminergic neurons in substantia nigra (SN), preventing early diagnosis…”
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Antidepressant activity of zinc: Further evidence for the involvement of the serotonergic system by Szewczyk, Bernadeta, Kotarska, Katarzyna, Siwek, Agata, Olech, Łukasz, Kuter, Katarzyna

“…The present study sought to further evaluate the role of the serotonergic system especially the postsynaptic 5-HT1A receptors (5-HT1AR) in the mechanism of…”
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Pramipexole but not imipramine or fluoxetine reverses the “depressive-like” behaviour in a rat model of preclinical stages of Parkinson's disease by Berghauzen-Maciejewska, Klemencja, Kuter, Katarzyna, Kolasiewicz, Wacław, Głowacka, Urszula, Dziubina, Anna, Ossowska, Krystyna, Wardas, Jadwiga

“…•6-OHDA-induced moderate dopamine lesion evoked depressive-like behaviour in rats.•Repeated pramipexole induced an antidepressant-like effect in…”
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6-OHDA injections into A8–A9 dopaminergic neurons modelling early stages of Parkinson's disease increase the harmaline-induced tremor in rats by Kolasiewicz, Wacław, Kuter, Katarzyna, Berghauzen, Klemencja, Nowak, Przemysław, Schulze, Gert, Ossowska, Krystyna

“…Abstract The aim of the present study was to examine the influence of a unilateral 6-hydroxydopamine (6-OHDA)-induced partial lesion of both the substantia…”
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