Search Results - "Kusy, Sophie"

Heme oxygenase-1 deletion affects stress erythropoiesis by Cao, Yu-An, Kusy, Sophie, Luong, Richard, Wong, Ronald J, Stevenson, David K, Contag, Christopher H

“…Homeostatic erythropoiesis leads to the formation of mature red blood cells under non-stress conditions, and the production of new erythrocytes occurs as the…”
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Development of B cells and erythrocytes is specifically impaired by the drug celastrol in mice by Kusy, Sophie, Ghosn, Eliver E B, Herzenberg, Leonore A, Contag, Christopher H

“…Celastrol, an active compound extracted from the root of the Chinese medicine "Thunder of God Vine" (Tripterygium wilfordii), exhibits anticancer, antioxidant…”
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WNT7a Induces E-Cadherin in Lung Cancer Cells by Ohira, Tatsuo, Gemmill, Robert M., Ferguson, Kevin, Kusy, Sophie, Roche, Joëlle, Brambilla, Elisabeth, Zeng, Chan, Baron, Anna, Bemis, Lynne, Erickson, Paul, Wilder, Elizabeth, Rustgi, Anil, Kitajewski, Jan, Gabrielson, Edward, Bremnes, Roy, Franklin, Wilbur, Drabkin, Harry A.

“…E-cadherin loss in cancer is associated with de-differentiation, invasion, and metastasis. Drosophila DE-cadherin is regulated by Wnt/β-catenin signaling,…”
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Semaphorin SEMA3F Has a Repulsing Activity on Breast Cancer Cells and Inhibits E-Cadherin-Mediated Cell Adhesion by Nasarre, Patrick, Kusy, Sophie, Constantin, Bruno, Castellani, Valérie, Drabkin, Harry A., Bagnard, Dominique, Roche, Joëlle

“…Previously, we demonstrated that loss of SEMA3F, a secreted semaphorin encoded in 3p21.3, is associated with higher stages in lung cancer and primary tumor…”
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Selective Suppression of In Vivo Tumorigenicity by Semaphorin SEMA3F in Lung Cancer Cells by Kusy, Sophie, Nasarre, Patrick, Chan, Daniel, Potiron, Vincent, Meyronet, David, Gemmill, Robert M., Constantin, Bruno, Drabkin, Harry A., Roche, Joëlle

“…Loss of the 3p21.3-encoded semaphorins, SEMA3B and SEMA3F is implicated in lung cancer development. Although both antagonize VEGF binding/response to…”
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NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia by Kusy, Sophie, Gerby, Bastien, Goardon, Nicolas, Gault, Nathalie, Ferri, Federica, Gérard, Delphine, Armstrong, Florence, Ballerini, Paola, Cayuela, Jean-Michel, Baruchel, André, Pflumio, Françoise, Roméo, Paul-Henri

“…TAL1 (also known as SCL) is expressed in >40% of human T cell acute lymphoblastic leukemias (T-ALLs). TAL1 encodes a basic helix-loop-helix transcription…”
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Adult Hematopoiesis is Regulated by TIF1γ, a Repressor of TAL1 and PU.1 Transcriptional Activity by Kusy, Sophie, Gault, Nathalie, Ferri, Federica, Lewandowski, Daniel, Barroca, Vilma, Jaracz-Ros, Agnieszka, Losson, Regine, Romeo, Paul-Henri

“…Crosstalk between transcription factors and cytokines precisely regulates tissue homeostasis. Transcriptional intermediary factor 1γ (TIF1γ) regulates…”
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NKX3.1 Is a Direct TAL1 Target Gene That Mediates the TAL1 Dependent Proliferation of Human T-Cell Acute Lymphoblastic Leukemia (T-ALL) by Kusy, Sophie, Goardon, Nicolas, Armstrong, Florence, Pflumio, Francoise, Romeo, paul-Henri

“…The TAL1/SCL gene encodes a bHLH (basic Helix-Loop-helix) protein that acts as a master gene in hematopoiesis. The TAL1/SCL gene is also the most frequently…”
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TIF1γ is a chief conductor of the hematopoietic system by Kusy, Sophie, Roméo, Paul-Henri

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p14 ARF , p15 INK4b and p16 INK4a Methylation Status in Chronic Myelogenous Leukemia by Kusy, Sophie, Larsen, Christian-Jacques, Roche, Joëlle

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p14ARF, p15INK4b and p16INK4a Methylation Status in Chronic Myelogenous Leukemia by Kusy, Sophie, Larsen, Christian-Jacques, Roche, Joëlle

“…The INK4 family of proteins p15INK4b, p14ARF and p16INK4a function as cell cycle inhibitors where they are involved in the inhibition of G1 phase progression…”
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Reporter gene technologies for imaging cell fates in hematopoiesis by Kusy, Sophie, Contag, Christopher H

“…Advances in noninvasive imaging technologies that allow for in vivo dynamic monitoring of cells and cellular function in living research subjects have revealed…”
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Semaphorin SEMA3F Has a Repulsing Activity on Breast CancerCells and Inhibits E-Cadherin–Mediated Cell Adhesion by Nasarre, Patrick, Kusy, Sophie, Constantin, Bruno, Castellani, Valérie, A. Drabkin, Harry, Bagnard, Dominique, Roche, Joëlle

“…Previously, we demonstrated that loss of SEMA3F, a secreted semaphorin encoded in 3p21.3, is associated with higher stages in lung cancer and primary tumor…”
Get full text

Semaphorin SEMA3F Has a Repulsing Activity on Breast Cancer Cells and Inhibits E-Cadherin-Mediated Cell Adhesion1 by Nasarre, Patrick, Kusy, Sophie, Constantin, Bruno, Castellani, Valérie, Drabkin, Harry A, Bagnard, Dominique, Roche, Joëlle

“…Previously, we demonstrated that loss of SEMA3F, a secreted semaphorin encoded in 3p21.3, is associated with higher stages in lung cancer and primary tumor…”
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Adult hematopoiesis is regulated by TIF1gamma, a repressor of TAL1 and PU.1 transcriptional activity by Kusy, Sophie, Gault, Nathalie, Ferri, Federica, Lewandowski, Daniel, Barroca, Vilma, Jaracz-Ros, Agnieszka, Losson, Regine, Romeo, Paul-Henri

“…Crosstalk between transcription factors and cytokines precisely regulates tissue homeostasis. Transcriptional intermediary factor 1gamma (TIF1gamma) regulates…”
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Selective Suppression of In Vivo Tumorigenicity by Semaphorin SEMA3F in Lung Cancer Cells1 by Kusy, Sophie, Nasarre, Patrick, Chan, Daniel, Potiron, Vincent, Meyronet, David, Gemmill, Robert M, Constantin, Bruno, Drabkin, Harry A, Roche, Joëlle

“…Loss of the 3p21.3-encoded semaphorins, SEMA3B and SEMA3F is implicated in lung cancer development. Although both antagonize VEGF binding/response to…”
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p14ARF,p15INK4b,andp16INK4amethylation status in chronic myelogenous leukemia by Kusy, Sophie, Cividin, Marie, Sorel, Nathalie, Brizard, Françoise, Guilhot, François, Brizard, André, Larsen, Christian, Roche, Joëlle

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p14ARF, p15INK4b, and p16INK4a methylation status in chronic myelogenous leukemia by Kusy, Sophie, Cividin, Marie, Sorel, Nathalie, Brizard, Françoise, Guilhot, François, Brizard, André, Larsen, Christian, Roche, Joëlle

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p14ARF,p15INK4b, and p16INK4amethylation status in chronic myelogenous leukemia by Kusy, Sophie, Cividin, Marie, Sorel, Nathalie, Brizard, Françoise, Guilhot, François, Brizard, André, Larsen, Christian, Roche, Joëlle

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Redundant functions but temporal and regional regulation of two alternatively spliced isoforms of Semaphorin 3F in the nervous system by Kusy, Sophie, Funkelstein, Lydiane, Bourgais, David, Drabkin, Harry, Rougon, Geneviève, Roche, Joëlle, Castellani, Valérie

“…SEMA3F is a secreted semaphorin that affects axon and cell guidance in the developing nervous system, and is also thought to have anti-tumor activity. Two…”
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