Search Results - "Kussauer, Sophie"

hiPSCs Derived Cardiac Cells for Drug and Toxicity Screening and Disease Modeling: What Micro- Electrode-Array Analyses Can Tell Us by Kussauer, Sophie, David, Robert, Lemcke, Heiko

“…Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes (CM) have been intensively used in drug development and disease modeling. Since…”
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Quality control in scRNA-Seq can discriminate pacemaker cells: the mtRNA bias by Galow, Anne-Marie, Kussauer, Sophie, Wolfien, Markus, Brunner, Ronald M., Goldammer, Tom, David, Robert, Hoeflich, Andreas

“…Single-cell RNA-sequencing (scRNA-seq) provides high-resolution insights into complex tissues. Cardiac tissue, however, poses a major challenge due to the…”
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Monitoring the maturation of the sarcomere network: a super-resolution microscopy-based approach by Skorska, Anna, Johann, Lisa, Chabanovska, Oleksandra, Vasudevan, Praveen, Kussauer, Sophie, Hillemanns, Maximilian, Wolfien, Markus, Jonitz-Heincke, Anika, Wolkenhauer, Olaf, Bader, Rainer, Lang, Hermann, David, Robert, Lemcke, Heiko

“…The in vitro generation of human cardiomyocytes derived from induced pluripotent stem cells (iPSC) is of great importance for cardiac disease modeling,…”
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BPIFB4 and its longevity-associated haplotype protect from cardiac ischemia in humans and mice by Cattaneo, Monica, Aleksova, Aneta, Malovini, Alberto, Avolio, Elisa, Thomas, Anita, Alvino, Valeria Vincenza, Kilcooley, Michael, Pieronne-Deperrois, Marie, Ouvrard-Pascaud, Antoine, Maciag, Anna, Spinetti, Gaia, Kussauer, Sophie, Lemcke, Heiko, Skorska, Anna, Vasudevan, Praveen, Castiglione, Stefania, Raucci, Angela, David, Robert, Richard, Vincent, Beltrami, Antonio Paolo, Madeddu, Paolo, Puca, Annibale Alessandro

“…Long-living individuals (LLIs) escape age-related cardiovascular complications until the very last stage of life. Previous studies have shown that a…”
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Heart rhythm in vitro : measuring stem cell-derived pacemaker cells on microelectrode arrays by Kussauer, Sophie, Dilk, Patrick, Elleisy, Moustafa, Michaelis, Claudia, Lichtwark, Sarina, Rimmbach, Christian, David, Robert, Jung, Julia

“…Cardiac arrhythmias have markedly increased in recent decades, highlighting the urgent need for appropriate test systems to evaluate the efficacy and safety of…”
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Customised micro-electrode array (MEA) test setup featuring a silicone-casted overlay with two chambers for separated cell seedings by Mau, Robert, Kussauer, Sophie, Matzmohr, Uta, David, Robert, Seitz, Hermann

“…Micro-electrode array (MEA) systems are noninvasive platforms for the investigation of electrophysiological properties of cell layers, such as spontaneously…”
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Printing of vessels for small functional tissues – a preliminary study by Polley, Christian, Kussauer, Sophie, David, Robert, Barkow, Phillip, Mau, Robert, Seitz, Hermann

“…Vascularization of bioprinted constructs to ensure sufficient nutrient supply still remains to be a significant task in the tissue engineering community. In…”
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ChiSCAT: Unsupervised Learning of Recurrent Cellular Micromotion Patterns from a Chaotic Speckle Pattern by Trelin, Andrii, Kussauer, Sophie, Weinbrenner, Paul, Clasen, Anja, David, Robert, Rimmbach, Christian, Reinhard, Friedemann

“…There is considerable evidence that action potentials are accompanied by “intrinsic optical signals”, such as a nanometer-scale motion of the cell membrane…”
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Influence of Conditioned Media on the Re-Differentiation Capacity of Human Chondrocytes in 3D Spheroid Cultures by Klinder, Annett, Kussauer, Sophie, Hiemer, Bettina, Wree, Andreas, Bader, Rainer, Jonitz-Heincke, Anika

“…A major challenge of cell-based therapy for cartilage lesions is the preservation of the chondrogenic phenotype during ex vivo cell cultivation. In this in…”
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ChiSCAT: unsupervised learning of recurrent cellular micro-motion patterns from a chaotic speckle pattern by Trelin, Andrii, Kussauer, Sophie, Weinbrenner, Paul, Clasen, Anja, David, Robert, Rimmbach, Christian, Reinhard, Friedemann

“…There is considerable evidence that action potentials are accompanied by "intrinsic optical signals", such as a nanometer-scale motion of the cell membrane…”
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