Search Results - "Kusnyerik, Akos"
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Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution
Published in Cell (17-09-2020)“…Human organoids recapitulating the cell-type diversity and function of their target organ are valuable for basic and translational research. We developed…”
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Subretinal Visual Implant Alpha IMS – Clinical trial interim report
Published in Vision research (Oxford) (01-06-2015)“…•Retina Implant Alpha IMS was applied in a clinical trial in 29 blind patients.•Visual acuity measured with Landolt C-rings reached up to 20/546.•Grating…”
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3
Subretinal electronic chips allow blind patients to read letters and combine them to words
Published in Proceedings of the Royal Society. B, Biological sciences (22-05-2011)“…A light-sensitive, externally powered microchip was surgically implanted subretinally near the macular region of volunteers blind from hereditary retinal…”
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Spatial resolution and perception of patterns mediated by a subretinal 16-electrode array in patients blinded by hereditary retinal dystrophies
Published in Investigative ophthalmology & visual science (30-07-2011)“…The perception of 11 persons blinded by hereditary retinal degeneration elicited by a subretinally implanted 16-electrode array used for light-independent…”
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5
The Predictive Role of Thyroid Hormone Levels for Early Diabetic Retinal Changes in Experimental Rat and Human Diabetes
Published in Investigative ophthalmology & visual science (19-05-2021)“…In diabetic subjects, early visual functional alterations such as color vision deficiencies (CVDs) are known to precede clinically apparent diabetic…”
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Safety and efficacy of subretinal visual implants in humans: methodological aspects
Published in Clinical and experimental optometry (01-01-2013)“…Replacing the function of visual pathway neurons by electronic implants is a novel approach presently explored by various groups in basic research and clinical…”
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Vision restoration with implants in retinal degenerations
Published in Orvosi hetilap (03-04-2011)“…Up until now there has been no available treatment for diseases causing the permanent impairment of retinal photoreceptors. Currently the development of the…”
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Artificial vision with wirelessly powered subretinal electronic implant alpha-IMS
Published in Proceedings of the Royal Society. B, Biological sciences (22-04-2013)“…This study aims at substituting the essential functions of photoreceptors in patients who are blind owing to untreatable forms of hereditary retinal…”
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Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans
Published in Nature neuroscience (01-08-2019)“…Targeting genes to specific neuronal or glial cell types is valuable for both understanding and repairing brain circuits. Adeno-associated viruses (AAVs) are…”
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Functional outcome in subretinal electronic implants depends on foveal eccentricity
Published in Investigative ophthalmology & visual science (19-11-2013)“…An active microelectronic subretinal implant, developed to replace the photoreceptive function in hereditary degenerations of the outer retina, has been…”
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Modeling of in vivo acousto-optic two-photon imaging of the retina in the human eye
Published in Optics express (07-09-2015)“…Our aim is to establish a novel combined acousto-optical method for in vivo imaging of the human retina with the two-photon microscope. In this paper we…”
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Changes in microchip position after implantation of a subretinal vision prosthesis in humans
Published in Acta ophthalmologica (Oxford, England) (01-09-2019)“…Purpose Retinal prosthetic devices have been developed to partially restore very low vision in legally blind patients with end‐stage hereditary retinal…”
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Congenital Nystagmus Gene FRMD7 Is Necessary for Establishing a Neuronal Circuit Asymmetry for Direction Selectivity
Published in Neuron (Cambridge, Mass.) (06-01-2016)“…Neuronal circuit asymmetries are important components of brain circuits, but the molecular pathways leading to their establishment remain unknown. Here we…”
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14
Optical Coherence Tomography in Patients With the Subretinal Implant Retina Implant Alpha IMS
Published in Ophthalmic surgery, lasers & imaging retina (01-12-2017)“…The aim of this study was to assess changes in retinal structure and thickness after subretinal implantation of the Retina Implant Alpha IMS (Retina Implant…”
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Positioning of electronic subretinal implants in blind retinitis pigmentosa patients through multimodal assessment of retinal structures
Published in Investigative ophthalmology & visual science (20-06-2012)“…To optimize methods for positioning subretinal visual implants, customizing their cable length, guiding them to the predetermined retinal position, and…”
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Artificial vision with wirelessly powered subretinal electronic implant alpha-IMS
Published in Proceedings of the Royal Society. B, Biological sciences (22-04-2013)“…This study aims at substituting the essential functions of photoreceptors in patients who are blind owing to untreatable forms of hereditary retinal…”
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Journal Article -
17
Long-term organotypic culture model of the post mortem adult human retina
Published in IBRO reports (01-09-2019)Get full text
Journal Article -
18
Restoration of useful vision up to letter recognition capabilities using subretinal microphotodiodes
Published in 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology (01-01-2010)“…Our group has developed a subretinal microphotodiode array for restoration of vision. In a clinical pilot study the array has been implanted in 11 patients…”
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Conference Proceeding Journal Article -
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Towards a mobile navigation device
Published in 2010 12th International Workshop on Cellular Nanoscale Networks and their Applications (CNNA 2010) (01-02-2010)“…This paper builds on our recently introduced concept of a portable, non-invasive navigation aid, called a bionic eyeglass, which assists the blind and visually…”
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Conference Proceeding -
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A mobile visual navigation device: New algorithms for crosswalk and pictogram recognition
Published in 2009 2nd International Symposium on Applied Sciences in Biomedical and Communication Technologies (01-11-2009)“…The ability of gaining visual information from the environment can be of utmost importance for visually impaired and blind people. Our experimental system,…”
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Conference Proceeding