Search Results - "Kushnir, Natasha"

Clinical development of plant-produced recombinant pharmaceuticals: Vaccines, antibodies and beyond by Yusibov, Vidadi, Streatfield, Stephen J., Kushnir, Natasha

“…In the last few years, plants have become an increasingly attractive platform for recombinant protein production. This builds on two decades of research,…”
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Breaking barriers in antibody discovery: harnessing divergent species for accessing difficult and conserved drug targets by Banik, Soma S.R., Kushnir, Natasha, Doranz, Benjamin J., Chambers, Ross

“…To exploit highly conserved and difficult drug targets, including multipass membrane proteins, monoclonal antibody discovery efforts increasingly rely on the…”
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Hybrid viral vectors for vaccine and antibody production in plants by Yusibov, Vidadi, Streatfield, Stephen J, Kushnir, Natasha, Roy, Gourgopal, Padmanaban, Annamalai

“…Plants have a demonstrated potential for large-scale, rapid production of recombinant proteins for diverse product applications, including subunit vaccines and…”
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Plant-based rapid production of recombinant subunit hemagglutinin vaccines targeting H1N1 and H5N1 influenza by Shoji, Yoko, Chichester, Jessica A., Jones, Mark, Manceva, Slobodanka D., Damon, Emily, Mett, Vadim, Musiychuk, Konstantin, Bi, Hong, Farrance, Christine, Shamloul, Moneim, Kushnir, Natasha, Sharma, Satish, Yusibov, Vidadi

“…In 2009, a novel H1N1 swine influenza virus was isolated from infected humans in Mexico and the United States, and rapidly spread around the world. Another…”
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Virus-like particles as a highly efficient vaccine platform: Diversity of targets and production systems and advances in clinical development by Kushnir, Natasha, Streatfield, Stephen J, Yusibov, Vidadi

“…Highlights ► Virus-like particles (VLPs) are a class of recombinant subunit vaccines. ► VLPs resemble native viruses but lack infectious genetic material. ►…”
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Dendritic cells, B cells and the regulation of antibody synthesis by MacPherson, Gordon, Kushnir, Natasha, Wykes, Michelle

“…Dendritic cells (DC) are usually thought of as antigen‐presenting cells for T cells. However, recent studies from our laboratory and those of others have shown…”
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Antibody Production in Plants and Green Algae by Yusibov, Vidadi, Kushnir, Natasha, Streatfield, Stephen J

“…Monoclonal antibodies (mAbs) have a wide range of modern applications, including research, diagnostic, therapeutic, and industrial uses. Market demand for mAbs…”
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Safety and Immunogenicity in Neonatal Mice of a Hyperattenuated Listeria Vaccine Directed against Human Immunodeficiency Virus by Rayevskaya, Marina, Kushnir, Natasha, Frankel, Fred R

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Plant-produced candidate countermeasures against emerging and reemerging infections and bioterror agents by Streatfield, Stephen J, Kushnir, Natasha, Yusibov, Vidadi

“…Despite progress in the prevention and treatment of infectious diseases, they continue to present a major threat to public health. The frequency of emerging…”
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B2 but Not B1 Cells Can Contribute to CD4+ T-Cell-Mediated Clearance of Rotavirus in SCID Mice by Kushnir, N, Bos, N A, Zuercher, A W, Coffin, S E, Moser, C A, Offit, P A, Cebra, J J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Advances and challenges in the development and production of effective plant-based influenza vaccines by Yusibov, Vidadi, Kushnir, Natasha, Streatfield, Stephen J

“…Influenza infections continue to present a major threat to public health. Traditional modes of influenza vaccine manufacturing are failing to satisfy the…”
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The small GTPase Rap1 promotes cell movement rather than stabilizes adhesion in epithelial cells responding to insulin-like growth factor I by Guvakova, Marina A, Lee, William S Y, Furstenau, Dana K, Prabakaran, Indira, Li, David C, Hung, Rupert, Kushnir, Natasha

“…The Ras-related GTPase Rap1 promotes cell adhesion and migration. Although the significance of Rap1 contribution to cell migration is increasingly being…”
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Monoassociation of SCID mice with helicobacter muridarum, but not four other enterics, provokes IBD upon receipt of T cells by Jiang, Han-Qing, Kushnir, Natasha, Christine Thurnheer, M., Bos, Nicolaas A., Cebra, John J.

“…Recently, a number of animal models for different aspects of inflammatory bowel disease (IBD) have been developed. The aim of this study was to use one of…”
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Early bacterial dependent induction of inducible nitric oxide synthase (iNOS) in epithelial cells upon transfer of CD45RB(high) CD4(+) T cells in a model for experimental colitis by Dijkstra, Gerard, Yuvaraj, Saravanan, Jiang, Han-Qing, Bun, Judy C A M, Moshage, Han, Kushnir, Natasha, Peppelenbosch, Maikel P, Cebra, John J, Bos, Nicolaas A

“…Both the role of inducible nitric oxide synthase (iNOS) in the development of inflammatory bowel disease (IBD) as well as the molecular details governing its…”
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Early bacterial dependent induction of inducible nitric oxide synthase (iNOS) in epithelial cells upon transfer of CD45RBhigh CD4+ T cells in a model for experimental colitis by Dijkstra, Gerard, Yuvaraj, Saravanan, Jiang, Han‐Qing, Bun, Judy C.A.M., Moshage, Han, Kushnir, Natasha, Peppelenbosch, Maikel P., Cebra, John J., Bos, Nicolaas A.

“…Background: Both the role of inducible nitric oxide synthase (iNOS) in the development of inflammatory bowel disease (IBD) as well as the molecular details…”
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Anti‐human immunodeficiency virus‐gag CD8+ memory T cells generated in vitro from Listeria‐immunized mice by Rayevskaya, Marina, Kushnir, Natasha, Frankel, Fred R.

“…Summary The goal of vaccination is the generation of immune memory, an immune state that permits rapid and intense recall responses to a pathogen. Considerable…”
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