Search Results - "Kushner, Max H"
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1
An AIB1 Isoform Alters Enhancer Access and Enables Progression of Early-Stage Triple-Negative Breast Cancer
Published in Cancer research (Chicago, Ill.) (15-08-2021)“…AIB1Δ4 is an N-terminally truncated isoform of the oncogene amplified in breast cancer 1 (AIB1) with increased expression in high-grade human ductal carcinoma…”
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2
PIM kinase inhibitor AZD1208 for treatment of MYC-driven prostate cancer
Published in JNCI : Journal of the National Cancer Institute (01-02-2015)“…PIM1 kinase is coexpressed with c-MYC in human prostate cancers (PCs) and dramatically enhances c-MYC-induced tumorigenicity. Here we examine the effects of a…”
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3
Loss of ANCO1 repression at AIB1/YAP targets drives breast cancer progression
Published in EMBO reports (07-01-2020)“…Transcription factors critical for the transition of normal breast epithelium to ductal carcinoma in situ (DCIS) and invasive breast cancer are not clearly…”
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Short- and Long-Term Effects of CDK4/6 Inhibition on Early-Stage Breast Cancer
Published in Molecular cancer therapeutics (01-12-2019)“…CDK4/6 inhibitors are used in the treatment of advanced estrogen receptor (ER)(+) breast cancer. Their efficacy in ER(-) and early-stage breast cancer is…”
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