Search Results - "Kushner, Irving"
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C-reactive protein - My perspective on its first half century, 1930-1982
Published in Frontiers in immunology (02-03-2023)“…C-reactive protein (CRP) was discovered in 1930 in the sera of patients during the acute phase of pneumococcal pneumonia and was so named because it bound to…”
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C-reactive Protein
Published in The Journal of biological chemistry (19-11-2004)“…C-reactive protein (CRP) is a phylogenetically highly conserved plasma protein, with homologs in vertebrates and many invertebrates, that participates in the…”
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Acute-Phase Proteins and Other Systemic Responses to Inflammation
Published in The New England journal of medicine (11-02-1999)“…A large number of changes, distant from the site or sites of inflammation and involving many organ systems, may accompany inflammation. In 1930 interest was…”
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The Complex Role of C-Reactive Protein in Systemic Lupus Erythematosus
Published in Journal of clinical medicine (13-12-2021)“…C-reactive protein (CRP) is well-known as a sensitive albeit unspecific biomarker of inflammation. In most rheumatic conditions, the level of this…”
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A unifying biologic explanation for “high‐sensitivity” C‐reactive protein and “low‐grade” inflammation
Published in Arthritis care & research (2010) (01-04-2010)Get full text
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The 4 Humors Erythrocyte Sedimentation: The Most Influential Observation in Medical History
Published in The American journal of the medical sciences (01-08-2013)Get full text
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An Ethiopian Pattern of Human Adaptation to High-Altitude Hypoxia
Published in Proceedings of the National Academy of Sciences - PNAS (24-12-2002)“…We describe, in Ethiopia, a third successful pattern of human adaptation to high-altitude hypoxia that contrasts with both the Andean "classic" (erythrocytosis…”
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It's time to redefine inflammation
Published in The FASEB journal (01-05-2017)“…ABSTRACT Inflammation has been defined for many years as the response to tissue injury and infection. We are now forced to reconsider this definition by the…”
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C‐reactive protein and systemic lupus erythematosus
Published in Arthritis and rheumatism (15-12-2008)Get full text
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Why Does C-Reactive Protein Predict Coronary Events?
Published in The American journal of medicine (01-07-2008)Get full text
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Low Serum Levels of 25-Hydroxyvitamin D Accompany Severe COVID-19 Because it is a Negative Acute Phase Reactant
Published in The American journal of the medical sciences (01-09-2021)Get full text
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STAT3 Participates in Transcriptional Activation of the C-reactive Protein Gene by Interleukin-6 (∗)
Published in The Journal of biological chemistry (19-04-1996)“…Interleukin-6 (IL-6) is the major cytokine inducing transcription of human C-reactive protein (CRP) during the acute phase response. STAT (signal transducers…”
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Regulation of the acute phase response by cytokines
Published in Perspectives in biology and medicine (01-06-1993)“…Cytokines appear to function as part of a complex regulatory network, a signaling language in which informational content resides in the combinations, and…”
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What does minor elevation of C-reactive protein signify?
Published in The American journal of medicine (01-02-2006)“…Reports of the predictive value of minor elevation of serum C-reactive protein (CRP) levels (between 3 and 10 mg/L) for atherosclerotic events have generated…”
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Teaching basic rheumatology
Published in Journal of rheumatology (01-04-2012)Get full text
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The Salpetriere Hospital in Paris and Its Role in the Beginnings of Modern Rheumatology
Published in Journal of rheumatology (01-09-2011)Get full text
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The constellation of vitamin D, the acute-phase response, and inflammation
Published in Cleveland Clinic journal of medicine (01-02-2023)Get full text
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Why 25-dehydroxyvitamin D is a negative acute-phase reactant
Published in Cleveland Clinic journal of medicine (01-09-2023)Get full text
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What should we regard as an "elevated" C-reactive protein level?
Published in Annals of internal medicine (18-08-2015)Get full text
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Quantitative and Qualitative Alterations of Acute-phase Proteins in Healthy Elderly Persons
Published in Age and ageing (01-05-1996)“…To assess acute-phase proteins in relation to ageing, we measured serum concentrations of C-reactive protein (CRP), serum amyloid-A protein (SAA), alpha-1 acid…”
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