Search Results - "Kusari, Jyotirmoy"

Inhibition of Vitreoretinal VEGF Elevation and Blood-Retinal Barrier Breakdown in Streptozotocin-Induced Diabetic Rats by Brimonidine by Kusari, Jyotirmoy, Zhou, Sheila X, Padillo, Edwin, Clarke, Kenneth G, Gil, Daniel W

“…To determine whether long-term brimonidine (BRI) treatment prevents the hyperglycemia-induced increase in vitreoretinal vascular endothelial growth factor…”
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Effect of brimonidine on retinal and choroidal neovascularization in a mouse model of retinopathy of prematurity and laser-treated rats by Kusari, Jyotirmoy, Padillo, Edwin, Zhou, Sheila X, Bai, Yanyan, Wang, Juanjuan, Song, Zhiming, Zhu, Meili, Le, Yun-Zheng, Gil, Daniel W

“…To determine whether chronic treatment with brimonidine (BRI) attenuates retinal vascular leakage and neovascularization in neonatal mice after exposure to…”
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Protein-tyrosine Phosphatase 1B Is a Negative Regulator of Insulin- and Insulin-like Growth Factor-I-stimulated Signaling by Kenner, Kathleen A., Anyanwu, Ezenta, Olefsky, Jerrold M., Kusari, Jyotirmoy

“…To understand the physiological role of protein-tyrosine phosphatase 1B (PTPase 1B) in insulin and insulin-like growth factor-I (IGF-I) signaling, we…”
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Protein-tyrosine phosphatase-1B acts as a negative regulator of insulin signal transduction by Byon, J C, Kusari, A B, Kusari, J

“…Insulin signaling involves a dynamic cascade of protein tyrosine phosphorylation and dephosphorylation. Most of our understanding of this process comes from…”
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Down-regulation of Insulin Signaling by Protein-tyrosine Phosphatase 1B Is Mediated by an N-terminal Binding Region by Dadke, Shrikrishna, Kusari, Jyotirmoy, Chernoff, Jonathan

“…Protein-tyrosine phosphatases (PTPs) play a major role in regulating insulin signaling. Among the PTPs that regulate this signaling pathway, PTP1B plays an…”
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Protein-Tyrosine Phosphatase 1B Complexes with the Insulin Receptor in Vivo and Is Tyrosine-phosphorylated in the Presence of Insulin by Bandyopadhyay, Debdutta, Kusari, Anasua, Kenner, Kathleen A., Liu, Feng, Chernoff, Jonathan, Gustafson, Thomas A., Kusari, Jyotirmoy

“…In response to insulin, protein-tyrosine phosphatase 1B (PTPase 1B) dephosphorylates 95- and 160-180-kDa tyrosine phosphorylated (PY) proteins (Kenner, K. A.,…”
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Elevated Expression and Activity of Protein-Tyrosine Phosphatase 1B in Skeletal Muscle of Insulin-Resistant Type II Diabetic Goto-Kakizaki Rats by Dadke, Shrikrishna S., Li, Hong C., Kusari, Anasua B., Begum, Najma, Kusari, Jyotirmoy

“…We investigated the cellular mechanism(s) of insulin resistance associated with non-insulin dependent diabetes mellitus (NIDDM) using skeletal muscles isolated…”
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Insulin-Induced Mitogen-Activated Protein (MAP) Kinase Phosphatase-1 (MKP-1) Attenuates Insulin-Stimulated MAP Kinase Activity: A Mechanism for the Feedback Inhibition of Insulin Signaling by Kusari, Anasua B, Byon, John, Bandyopadhyay, Debdutta, Kenner, Kathleen A, Kusari, Jyotirmoy

“…Insulin signaling involves the transient activation/inactivation of various proteins by a cycle of phosphorylation/dephosphorylation. This dynamic process is…”
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Bioenergetic modulation with the mitochondria uncouplers SR4 and niclosamide prevents proliferation and growth of treatment-naïve and vemurafenib-resistant melanomas by Figarola, James L, Singhal, Jyotsana, Singhal, Sharad, Kusari, Jyotirmoy, Riggs, Arthur

“…BRAF mutations are detected in >50% of all melanomas. These mutations impair the LKB1-AMPK signaling, an important metabolic pathway associated with cell…”
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Effect of Memantine on Neuroretinal Function and Retinal Vascular Changes of Streptozotocin-Induced Diabetic Rats by Kusari, Jyotirmoy, Zhou, Sheila, Padillo, Edwin, Clarke, Kenneth G, Gil, Daniel W

“…To test whether chronic memantine (MEM) treatment improves retinal function and prevents neurodegeneration and vascular changes in the retinas of…”
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Protein tyrosine phosphatase 1B interacts with the activated insulin receptor by Seely, B L, Staubs, P A, Reichart, D R, Berhanu, P, Milarski, K L, Saltiel, A R, Kusari, J, Olefsky, J M

“…Protein tyrosine phosphatase 1B (PTP1B) is a protein tyrosine phosphatase of unknown function, although increasing evidence supports a role for this…”
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Phosphorylation and activation of protein tyrosine phosphatase (PTP) 1B by insulin receptor by Dadke, S, Kusari, A, Kusari, J

“…We have previously reported a direct in vivo interaction between the activated insulin receptor and protein-tyrosine phosphatase-1B (PTP1B), which leads to an…”
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Skeletal muscle protein tyrosine phosphatase activity and tyrosine phosphatase 1B protein content are associated with insulin action and resistance by KUSARI, J, KENNER, K. A, KYO-II SUH, HILL, D. E, HENRY, R. R

“…Particulate and cytosolic protein tyrosine phosphatase (PTPase) activity was measured in skeletal muscle from 15 insulin-sensitive subjects and 5…”
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Regulation of protein tyrosine phosphatases by insulin and insulin-like growth factor I by Kenner, K A, Hill, D E, Olefsky, J M, Kusari, J

“…In this study, we have examined the effects of insulin and insulin-like growth factor (IGF)-I on protein tyrosine phosphatase (PTPase) activity in rat L6…”
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Regulation of growth factor-induced signaling by protein-tyrosine-phosphatases by Byon, J C, Kenner, K A, Kusari, A B, Kusari, J

“…The binding of a growth factor to its specific receptor catalyzes a complex cascade of intracellular signaling events, characterized by changes in the…”
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Insulin regulates MAP kinase phosphatase-1 induction in Hirc B cells via activation of both extracellular signal-regulated kinase (ERK) and c-Jun-N-terminal kinase (JNK) by Byon, J C, Dadke, S S, Rulli, S, Kusari, A B, Kusari, J

“…Previously, we have reported that insulin induces the expression of the dual-specificity tyrosine phosphatase Mitogen-activated protein (MAP) kinase…”
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Gene induction by interferons and double-stranded RNA: selective inhibition by 2-aminopurine by TIWARI, R. K, JYOTIRMOY KUSARI, RAKESH KUMAR, SEN, G. C

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cloning, sequencing, and expression of two murine 2'-5'-oligoadenylate synthetases. Structure-function relationships by GHOSH, S. K, KUSARI, J, BANDYOPADHYAY, S. K, SAMANTA, H, KUMAR, R, SEN, G. C

“…2'-5'-oligoadenylate synthetases constitute a multimember family of interferon-inducible enzymes which need double-stranded RNA as an obligatory cofactor. We…”
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cDNA Sequence Analysis of the Human Brain Insulin Receptor by Kenner, K.A., Kusari, J., Heidenreich, K.A.

“…Brain tissue mRNA was amplified using polymerase chain reaction (PCR) with eight overlapping sets of primers that span the cDNA coding sequence for the human…”
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Insulin resistance and diabetes due to different mutations in the tyrosine kinase domain of both insulin receptor gene alleles by Kusari, J, Takata, Y, Hatada, E, Freidenberg, G, Kolterman, O, Olefsky, J M

“…Mutations in the insulin receptor gene can lead to in vivo and in vitro insulin resistance and can be the cause of diabetes mellitus in selected patients. We…”
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