Search Results - "Kurup, Jiji Thulaseedhara"
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Genetic analyses in multiplex families confirms chromosome 5q35 as a risk locus for Alzheimer's Disease in individuals of African Ancestry
Published in Neurobiology of aging (01-01-2024)“…There is a paucity of genetic studies of Alzheimer Disease (AD) in individuals of African Ancestry, despite evidence suggesting increased risk of AD in the…”
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A large‐scale genome‐wide association study of early‐onset Alzheimer disease
Published in Alzheimer's & dementia (01-12-2022)“…Background Early‐onset (≤65 years old) Alzheimer Disease (EOAD), which accounts for approximately 10% of all AD cases, is sometimes equated with dominantly…”
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Meta‐analysis employing the African Genome Resources panel identifies novel Alzheimer disease risk loci in African Americans
Published in Alzheimer's & dementia (01-12-2022)“…Background In the largest Alzheimer disease (AD) genome‐wide association studies to date for African‐Americans (AA; Reitz et al. JAMA 2013; Kunkle at al. JAMA…”
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Heritability analyses show partial genetic overlap between (non‐Mendelian) early and late onset Alzheimer disease due to an intriguing APOE effect
Published in Alzheimer's & dementia (01-12-2021)“…Background Alzheimer disease (AD) is a degenerative brain disease, being the most common cause of progressive dementia and listed as the sixth leading cause of…”
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A large‐scale, whole genome sequencing study of unexplained early‐onset Alzheimer disease
Published in Alzheimer's & dementia (01-12-2021)“…Background Genomic studies of Alzheimer disease (AD) have primarily focused on non‐Hispanic White (NHW) participants affected by the late‐onset form (LOAD;…”
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