Search Results - "Kurundkar, Ashish R."

Probiotic Bacteria Induce Maturation of Intestinal Claudin 3 Expression and Barrier Function by Patel, Ravi M, Myers, Loren S, Kurundkar, Ashish R, Maheshwari, Akhil, Nusrat, Asma, Lin, Patricia W

“…An immature intestinal epithelial barrier may predispose infants and children to many intestinal inflammatory diseases, such as infectious enteritis,…”
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SIRT3 diminishes inflammation and mitigates endotoxin-induced acute lung injury by Kurundkar, Deepali, Kurundkar, Ashish R, Bone, Nathaniel B, Becker, Jr, Eugene J, Liu, Wanqu, Chacko, Balu, Darley-Usmar, Victor, Zmijewski, Jaroslaw W, Thannickal, Victor J

“…Acute lung injury (ALI) is characterized by exuberant proinflammatory responses and mitochondrial dysfunction. However, the link between mitochondrial…”
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Plasma concentrations of inflammatory cytokines rise rapidly during ECMO-related SIRS due to the release of preformed stores in the intestine by McILwain, R Britt, Timpa, Joseph G, Kurundkar, Ashish R, Holt, David W, Kelly, David R, Hartman, Yolanda E, Neel, Mary Lauren, Karnatak, Rajendra K, Schelonka, Robert L, Anantharamaiah, G M, Killingsworth, Cheryl R, Maheshwari, Akhil

“…Extracorporeal membrane oxygenation (ECMO) is a life-saving support system used in neonates and young children with severe cardiorespiratory failure. Although…”
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Apolipoprotein A-I mimetic 4F alters the function of human monocyte-derived macrophages by Smythies, Lesley E, White, C Roger, Maheshwari, Akhil, Palgunachari, M N, Anantharamaiah, G M, Chaddha, Manjula, Kurundkar, Ashish R, Datta, Geeta

“…HDL and its major protein component apolipoprotein A-I (apoA-I) exert anti-inflammatory effects, inhibit monocyte chemotaxis/adhesion, and reduce vascular…”
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Epithelial cells in fetal intestine produce chemerin to recruit macrophages by Maheshwari, Akhil, Kurundkar, Ashish R, Shaik, Sadiq S, Kelly, David R, Hartman, Yolanda, Zhang, Wei, Dimmitt, Reed, Saeed, Shehzad, Randolph, David A, Aprahamian, Charles, Datta, Geeta, Ohls, Robin K

“…Macrophages are first seen in the fetal intestine at 11-12 wk and rapidly increase in number during the 12- to 22-wk period of gestation. The development of…”
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The matricellular protein CCN1 enhances TGF‐β1/SMAD3‐dependent profibrotic signaling in fibroblasts and contributes to fibrogenic responses to lung injury by Kurundkar, Ashish R., Kurundkar, Deepali, Rangarajan, Sunad, Locy, Morgan L., Zhou, Yong, Liu, Rui‐Ming, Zmijewski, Jaroslaw, Thannickal, Victor J.

“…ABSTRACT Matricellular proteins mediate pleiotropic effects during tissue injury and repair. CCN1 is a matricellular protein that has been implicated in…”
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Nicotinamide N-methyltransferase mediates lipofibroblast–myofibroblast transition and apoptosis resistance by Rehan, Mohammad, Deskin, Brian, Kurundkar, Ashish R., Yadav, Santosh, Matsunaga, Yasuka, Manges, Justin, Smith, Nia, Dsouza, Kevin G., Burow, Matthew E., Thannickal, Victor J.

“…Metabolism controls cellular phenotype and fate. In this report, we demonstrate that nicotinamide N-methyltransferase (NNMT), a metabolic enzyme that regulates…”
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The senescence-associated matricellular protein CCN1 in plasma of human subjects with idiopathic pulmonary fibrosis by Kulkarni, Tejaswini, Kurundkar, Ashish R., Kim, Young-il, de Andrade, Joao, Luckhardt, Tracy, Thannickal, Victor J.

“…Cellular senescence has been linked to the pathogenesis of idiopathic pulmonary fibrosis (IPF). CCN1 is a matricellular protein that has been shown to induce…”
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Clinical and histopathological correlates of intestinal repair in preterm infants following surgical necrotizing enterocolitis by Garg, Parvesh Mohan, Middleton, Charles, Zhang, Mengna, Paschal, Jaslyn L., Kurundkar, Ashish R., Sonani, Hardik, Varshney, Neha, Hillegass, William B.

“…We sought to determine the clinical and histopathological factors linked with intestinal repair and its correlation with clinical outcomes in preterm infants…”
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Gut mucosal injury in neonates is marked by macrophage infiltration in contrast to pleomorphic infiltrates in adult: evidence from an animal model by MohanKumar, Krishnan, Kaza, Niroop, Jagadeeswaran, Ramasamy, Garzon, Steven A, Bansal, Anchal, Kurundkar, Ashish R, Namachivayam, Kopperuncholan, Remon, Juan I, Bandepalli, C Rekha, Feng, Xu, Weitkamp, Joern-Hendrik, Maheshwari, Akhil

“…Necrotizing enterocolitis (NEC) is an inflammatory bowel necrosis of premature infants. In tissue samples of NEC, we identified numerous macrophages and a few…”
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Focal adhesion kinase signaling determines the fate of lung epithelial cells in response to TGF-β by Ding, Qiang, Subramanian, Indhu, Luckhardt, Tracy R, Che, Pulin, Waghray, Meghna, Zhao, Xue-Ke, Bone, Nathaniel, Kurundkar, Ashish R, Hecker, Louise, Hu, Meng, Zhou, Yong, Horowitz, Jeffrey C, Vittal, Ragini, Thannickal, Victor J

“…Alveolar epithelial cell (AEC) injury and apoptosis are prominent pathological features of idiopathic pulmonary fibrosis (IPF). There is evidence of AEC…”
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Restoration of SIRT3 gene expression by airway delivery resolves age-associated persistent lung fibrosis in mice by Rehan, Mohammad, Kurundkar, Deepali, Kurundkar, Ashish R, Logsdon, Naomi J, Smith, Samuel R, Chanda, Diptiman, Bernard, Karen, Sanders, Yan Y, Deshane, Jessy S, Dsouza, Kevin G, Rangarajan, Sunad, Zmijewski, Jaroslaw W, Thannickal, Victor J

“…Aging is a risk factor for progressive fibrotic disorders involving diverse organ systems, including the lung. Idiopathic pulmonary fibrosis, an age-associated…”
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Epidermal growth factor reduces autophagy in intestinal epithelium and in the rat model of necrotizing enterocolitis by Maynard, Andrew A, Dvorak, Katerina, Khailova, Ludmila, Dobrenen, Holly, Arganbright, Kelly M, Halpern, Melissa D, Kurundkar, Ashish R, Maheshwari, Akhil, Dvorak, Bohuslav

“…Necrotizing enterocolitis (NEC) is a devastating intestinal disease of premature infants. Epidermal growth factor (EGF) is one of the most promising candidates…”
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VEGF mRNA and protein concentrations in the developing human eye by Ma, Irene T., McConaghy, Suzanne, Namachivayam, Kopperuncholan, Halloran, Brian A., Kurundkar, Ashish R., MohanKumar, Krishnan, Maheshwari, Akhil, Ohls, Robin K.

“…Background: Vascular endothelial growth factor (VEGF), a well-characterized regulator of angiogenesis, has been mechanistically implicated in retinal…”
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Extracorporeal Membrane Oxygenation Causes Loss of Intestinal Epithelial Barrier in the Newborn Piglet by Kurundkar, Ashish R, Killingsworth, Cheryl R, McIlwain, R Britt, Timpa, Joseph G, Hartman, Yolanda E, He, Dongning, Karnatak, Rajendra K, Neel, Mary L, Clancy, John P, Anantharamaiah, G M, Maheshwari, Akhil

“…Extracorporeal membrane oxygenation (ECMO) is an important life-support system used in neonates and young children with intractable cardiorespiratory failure…”
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Intestinal epithelial apoptosis initiates gut mucosal injury during extracorporeal membrane oxygenation in the newborn piglet by MohanKumar, Krishnan, Killingsworth, Cheryl R, Britt McILwain, R, Timpa, Joseph G, Jagadeeswaran, Ramasamy, Namachivayam, Kopperuncholan, Kurundkar, Ashish R, Kelly, David R, Garzon, Steven A, Maheshwari, Akhil

“…Neonates and young infants exposed to extracorporeal circulation during extracorporeal membrane oxygenation (ECMO) and cardiopulmonary bypass are at risk of…”
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Cyclosporine a mediates pathogenesis of aggressive cutaneous squamous cell carcinoma by augmenting epithelial-mesenchymal transition: Role of TGFβ signaling pathway by Walsh, Stephanie B., Xu, Jianmin, Xu, Hui, Kurundkar, Ashish R., Maheshwari, Akhil, Grizzle, William E., Timares, Laura, Huang, Conway C., Kopelovich, Levy, Elmets, Craig A., Athar, Mohammad

“…Organ transplant recipients (OTRs) develop multiple aggressive and metastatic non‐melanoma skin cancers (NMSCs). Yet, the underlying mechanism remains elusive…”
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Editor’s Focus by Ma, Irene T., McConaghy, Suzanne, Namachivayam, Kopperuncholan, Halloran, Brian A., Kurundkar, Ashish R., MohanKumar, Krishnan, Maheshwari, Akhil, Ohls, Robin K.

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Lactobacillus rhamnosus GG accelerates intestinal barrier maturation in developing mice through induction of tight junction proteins by Patel, Ravi Mangal, Myers, Loren E, Qian, Tian, Kurundkar, Ashish R, Maheshwari, Akhil, Nusrat, Asma, Lin, Patricia W

“…Necrotizing enterocolitis (NEC) is a devastating disease affecting preterm infants. Probiotics may prevent NEC by strengthening the immature epithelial barrier…”
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Cyclosporine a mediates pathogenesis of aggressive cutaneous squamous cell carcinoma by augmenting epithelial-mesenchymal transition: Role of TGF[beta] signaling pathway by Walsh, Stephanie B, Xu, Jianmin, Xu, Hui, Kurundkar, Ashish R, Maheshwari, Akhil, Grizzle, William E, Timares, Laura, Huang, Conway C, Kopelovich, Levy, Elmets, Craig A, Athar, Mohammad

“…Organ transplant recipients (OTRs) develop multiple aggressive and metastatic non-melanoma skin cancers (NMSCs). Yet, the underlying mechanism remains elusive…”
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