Search Results - "Kurtoglu, Senem"
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Prostate cancer sheds the αvβ3 integrin in vivo through exosomes
Published in Matrix biology (01-04-2019)“…The αvβ3 integrin has been shown to promote aggressive phenotypes in many types of cancers, including prostate cancer. We show that GFP-labeled αvβ3 derived…”
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Journal Article -
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Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer
Published in Matrix biology (01-09-2018)“…Therapeutic approaches aimed at curing prostate cancer are only partially successful given the occurrence of highly metastatic resistant phenotypes that…”
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Journal Article -
3
Transforming growth factor-[beta] signaling induced during prostate cancer cell death and neuroendocrine differentiation is mediated by bone marrow stromal cells
Published in The Prostate (01-11-2015)“…Introduction Prostate cancer that has metastasized to bone undergoes critical interactions with bone marrow stromal cells (BMSCs), ultimately promoting tumor…”
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Journal Article -
4
Transforming growth factor-β signaling induced during prostate cancer cell death and neuroendocrine differentiation is mediated by bone marrow stromal cells
Published in The Prostate (01-11-2015)“…Introduction Prostate cancer that has metastasized to bone undergoes critical interactions with bone marrow stromal cells (BMSCs), ultimately promoting tumor…”
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Journal Article -
5
Increased TGF-β1-mediated suppression of growth and motility in castrate-resistant prostate cancer cells is consistent with Smad2/3 signaling
Published in The Prostate (01-09-2012)“…BACKGROUND Elevated TGF‐β levels are associated with prostate cancer progression. Although TGF‐β is a tumor suppressor for normal epithelial and early‐stage…”
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Journal Article -
6
Exosomal avß6 integrin is required for monocyte M2 polarization in prostate cancer
Published in Matrix biology (01-09-2018)“…Therapeutic approaches aimed at curing prostate cancer are only partially successful given the occurrence of highly metastatic resistant phenotypes that…”
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Journal Article -
7
Modulation of paracrine interactions between prostate cancer cells and bone marrow stromal cells by transforming growth factor-beta signaling during colonization of bone
Published 01-01-2014“…Prostate cancer (PCa) is the most prevalent cancer and the second leading cause of cancer related death for men in the United States. Death is primarily due to…”
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Dissertation -
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Abstract 4256: Neuroendocrine, stem, and stromal cell interactions involved in the organization of the normal colonic stem cell niche which become disorganized during colon tumorigenesis
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…In development of colorectal cancer (CRC), stem cell (SC) overpopulation underlies tumor initiation and progression, but it is incompletely understood which…”
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Journal Article