Primary ovarian fibrosarcoma – An unusual tumor in an adolescent: Case report and review of the pediatric literature

Primary ovarian fibrosarcoma – An unusual tumor in an adolescent: Case report and review of the pediatric literature

Abstract Background Primary ovarian fibrosarcomas are rare and usually observed in perimenopausal and postmenopausal women. Up-to-date, there are only 3 reports of ovarian fibrosarcoma in childhood and adolescence in English literature. In this report, we aimed to present the first pediatric case wi...

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Bibliographic Details
Published in:Journal of pediatric & adolescent gynecology Vol. 30; no. 6; pp. 655 - 658
Main Authors: Kurtmen, Bade T, Dokumcu, Zafer, Divarci, Emre, Serin, Gürdeniz, Ergun, Orkan, Ozok, Geylani, Celik, Ahmet
Format: Journal Article
Language:English
Published: United States Elsevier Inc 01-12-2017
Subjects:
Adolescent
Chemotherapy, Adjuvant
Child
Female
Fibrosarcoma - therapy
Humans
Obstetrics and Gynecology
Ovarian fibrosarcoma
Ovarian Neoplasms - pathology
Ovarian Neoplasms - therapy
Ovarian sarcoma
Pediatrics
Salpingo-oophorectomy - methods
ovarian fibrosarcoma
adolescent
ovarian sarcoma
child
Ovarian sarcoma
Ovarian fibrosarcoma
Child
Adolescent
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Summary:Abstract Background Primary ovarian fibrosarcomas are rare and usually observed in perimenopausal and postmenopausal women. Up-to-date, there are only 3 reports of ovarian fibrosarcoma in childhood and adolescence in English literature. In this report, we aimed to present the first pediatric case with advanced staged primary ovarian fibrosarcoma and to compare with previous cases. Case A 14-year-old teenage girl was admitted due to a giant abdominal mass. Imaging techniques revealed a giant heterogeneous and vascular ovarian mass. Salpingo-oophorectomy along with staging procedures were performed. Pathologic examination confirmed grade III ovarian fibrosarcoma with severe nuclear atypia and high mitotic count. Due to pulmonary metastasis, she received four courses of adjuvant combination chemotherapy (Ewing’s protocole). The patient stood the treatment well and is disease-free in two years of follow-up. Conclusion Fibrosarcoma of the ovary is an uncommon neoplasm with poor prognosis. To our knowledge, the presented patient is the first pediatric case with advanced staged primary ovarian fibrosarcoma to be treated with surgery and adjuvant chemotherapy.
Bibliography:ObjectType-Case Study-3
SourceType-Scholarly Journals-1
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ObjectType-Review-1
ObjectType-Feature-5
ObjectType-Report-2
ObjectType-Article-4
ISSN:1083-3188
1873-4332
DOI:10.1016/j.jpag.2017.05.003