Search Results - "Kurstjens, Steef"

Deep learning with robustness to missing data: A novel approach to the detection of COVID-19 by Çallı, Erdi, Murphy, Keelin, Kurstjens, Steef, Samson, Tijs, Herpers, Robert, Smits, Henk, Rutten, Matthieu, van Ginneken, Bram

“…In the context of the current global pandemic and the limitations of the RT-PCR test, we propose a novel deep learning architecture, DFCN (Denoising Fully…”
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Rapid identification of SARS-CoV-2-infected patients at the emergency department using routine testing by Kurstjens, Steef, van der Horst, Armando, Herpers, Robert, Geerits, Mick W L, Kluiters-de Hingh, Yvette C M, Göttgens, Eva-Leonne, Blaauw, Martinus J T, Thelen, Marc H M, Elisen, Marc G L M, Kusters, Ron

“…The novel coronavirus disease 19 (COVID-19), caused by SARS-CoV-2, spreads rapidly across the world. The exponential increase in the number of cases has…”
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Magnesium increases insulin-dependent glucose uptake in adipocytes by Oost, Lynette J., Kurstjens, Steef, Ma, Chao, Hoenderop, Joost G. J., Tack, Cees J., de Baaij, Jeroen H. F.

“…Background Type 2 diabetes (T2D) is characterized by a decreased insulin sensitivity. Magnesium (Mg 2+ ) deficiency is common in people with T2D. However, the…”
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Diabetes-induced hypomagnesemia is not modulated by metformin treatment in mice by Kurstjens, Steef, Bouras, Hacene, Overmars-Bos, Caro, Kebieche, Mohamed, Bindels, René J. M., Hoenderop, Joost G. J., de Baaij, Jeroen H. F.

“…Approximately 30% of patients with type 2 diabetes mellitus (T2D) have hypomagnesemia (blood magnesium (Mg 2+ ) concentration <0.7 mmol/L). In T2D patients,…”
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ChatGPT and Generating a Differential Diagnosis Early in an Emergency Department Presentation by Berg, Hidde Ten, van Bakel, Bram, van de Wouw, Lieke, Jie, Kim E, Schipper, Anoeska, Jansen, Henry, O'Connor, Rory D, van Ginneken, Bram, Kurstjens, Steef

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In reply by Berg, Hidde ten, van Bakel, Bram, van de Wouw, Lieke, Jie, Kim E., Schipper, Anoeska, Jansen, Henry, O’Connor, Rory D., van Ginneken, Bram, Kurstjens, Steef

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Serum magnesium and the risk of prediabetes: a population-based cohort study by Kieboom, Brenda C. T., Ligthart, Symen, Dehghan, Abbas, Kurstjens, Steef, de Baaij, Jeroen H. F., Franco, Oscar H., Hofman, Albert, Zietse, Robert, Stricker, Bruno H., Hoorn, Ewout J.

“…Aims/hypothesis Previous studies have found an association between serum magnesium and incident diabetes; however, this association may be due to reverse…”
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Machine Learning-Based Prediction of Hemoglobinopathies Using Complete Blood Count Data by Schipper, Anoeska, Rutten, Matthieu, van Gammeren, Adriaan, Harteveld, Cornelis L, Urrechaga, Eloísa, Weerkamp, Floor, den Besten, Gijs, Krabbe, Johannes, Slomp, Jennichjen, Schoonen, Lise, Broeren, Maarten, van Wijnen, Merel, Huijskens, Mirelle J A J, Koopmann, Tamara, van Ginneken, Bram, Kusters, Ron, Kurstjens, Steef

“…Hemoglobinopathies, the most common inherited blood disorder, are frequently underdiagnosed. Early identification of carriers is important for genetic…”
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Determinants of hypomagnesemia in patients with type 2 diabetes mellitus by Kurstjens, Steef, de Baaij, Jeroen H F, Bouras, Hacene, Bindels, René J M, Tack, Cees J J, Hoenderop, Joost G J

“…Background Hypomagnesemia (plasma magnesium (Mg2+) concentration <0.7 mmol/L) has been described in patients with type 2 diabetes. Polypharmacy is inevitable…”
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Discrepancies in corrected calcium versus ionised calcium in a geriatric population: an observational study by Suryapranata, Alexandra P S P, Keijsers, Carolina J P W, Kurstjens, Steef, Van Strien, Astrid M

“…Calcium can be measured as ionised (Ca-ionised) or albumin-adjusted total calcium (Ca-albumin). Current clinical guidelines predominantly utilise Ca-albumin,…”
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Serum Magnesium Is Inversely Associated With Heart Failure, Atrial Fibrillation, and Microvascular Complications in Type 2 Diabetes by Oost, Lynette J., van der Heijden, Amber A.W.A., Vermeulen, Emma A., Bos, Caro, Elders, Petra J.M., Slieker, Roderick C., Kurstjens, Steef, van Berkel, Miranda, Hoenderop, Joost G.J., Tack, Cees J., Beulens, Joline W.J., de Baaij, Jeroen H.F.

“…OBJECTIVE We investigated whether serum magnesium (Mg2+) was prospectively associated with macro- or microvascular complications and mediated by glycemic…”
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Lower plasma calcium associated with COVID-19, but not with disease severity: a two-centre retrospective cohort study by Deodatus, Jan Arne, Kooistra, Simone Anna, Kurstjens, Steef, Mossink, Joram Cornèl Leon, van Dijk, Joris David, Groeneveld, Paul Hendrik Pieter, van der Kolk, Brigitta (Britt) Yarine Maxime

“…Previous studies indicate hypocalcaemia as a potential diagnostic and prognostic marker of corona-virus disease 2019 (COVID-19). Our aim was to investigate…”
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Validation of the Hem-Col capillary blood collection system for routine laboratory analyses by Kurstjens, Steef, den Besten, Marjon J, van Dartel, Dorien A M, van Gend, Marloes C C, Meerts, Lizzy, Hoedemakers, Rein M J

“…At home collection of capillary blood using Hem-Col tubes (Labonovum) could offer a solution to patients with chronic conditions, who require frequent…”
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Magnesium deficiency prevents high-fat-diet-induced obesity in mice by Kurstjens, Steef, van Diepen, Janna A., Overmars-Bos, Caro, Alkema, Wynand, Bindels, René J. M., Ashcroft, Frances M., Tack, Cees J. J., Hoenderop, Joost G. J., de Baaij, Jeroen H. F.

“…Aims/hypothesis Hypomagnesaemia (blood Mg 2+ <0.7 mmol/l) is a common phenomenon in individuals with type 2 diabetes. However, it remains unknown how a low…”
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Hypomagnesemia in Type 2 Diabetes is Correlated with Insulin Resistance and Changes in Lipid Metabolism in Patients and Mice by Kurstjens, Steef, de Baaij, Jeroen, van Diepen, Janna, Overmars‐Bos, Caro, Bouras, Hacene, Bindels, René, Tack, Cees, Hoenderop, Joost

“…Abstract only Background Hypomagnesemia (plasma magnesium (Mg 2+ ) concentration <0.7 mmol/L) is a common phenomenon in patients with type 2 diabetes…”
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In reply by Berg, Hidde Ten, van Bakel, Bram, van de Wouw, Lieke, Jie, Kim E, Schipper, Anoeska, Jansen, Henry, O'Connor, Rory D, van Ginneken, Bram, Kurstjens, Steef

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In reply by Berg, Hidde Ten, van Bakel, Bram, van de Wouw, Lieke, Jie, Kim E, Schipper, Anoeska, Jansen, Henry, O'Connor, Rory D, van Ginneken, Bram, Kurstjens, Steef

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Renal phospholipidosis and impaired magnesium handling in high‐fat‐diet–fed mice by Kurstjens, Steef, Smeets, Bart, Overmars-Bos, Caro, Dijkman, Henry B., Braanker, Dirk J. W., Bel, Thomas, Bindels, René J. M., Tack, Cees J. J., Hoenderop, Joost G. J., Baaij, Jeroen H. F.

“…ABSTRACT Hypomagnesemia (blood Mg2+ concentration <0.7 mM) is a common electrolyte disorder in patients with type 2 diabetes (T2D), but the etiology remains…”
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The Succinate Receptor 1 is a Physiological Regulator of the Renin‐Angiontensin Aldosterone System by Carmone, Claudia, Robben, Joris, Ariza, Ana, Bekkenkamp, Melissa, Kurstjens, Steef, Devuyst, Olivier, Deen, Peter

“…Abstract only It has been shown that oxidative cell stress in diabetes type I (DMI) induces tubular release of mitochondrial succinate and that subsequent…”
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Metformin regulates TRPM6, a potential explanation for magnesium imbalance in type 2 diabetes patients by Bouras, Hacene, Roig, Sara R, Kurstjens, Steef, Tack, Cees J J, Kebieche, Mohamed, de Baaij, Jeroen H F, Hoenderop, Joost G J

“…Metformin therapy is associated with lower serum magnesium (Mg ) levels in type 2 diabetes patients. The TRPM6 channel determines the fine-tuning of Mg…”
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