Search Results - "Kurpad, Shekar N."

Emerging Safety of Intramedullary Transplantation of Human Neural Stem Cells in Chronic Cervical and Thoracic Spinal Cord Injury by Levi, Allan D, Okonkwo, David O, Park, Paul, Jenkins, Arthur L, Kurpad, Shekar N, Parr, Ann M, Ganju, Aruna, Aarabi, Bizhan, Kim, Dong, Casha, Steven, Fehlings, Michael G, Harrop, James S, Anderson, Kim D, Gage, Allyson, Hsieh, Jane, Huhn, Stephen, Curt, Armin, Guzman, Raphael

“…Abstract BACKGROUND Human central nervous system stem cells (HuCNS-SC) are multipotent adult stem cells with successful engraftment, migration, and…”
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Alterations in Cortical Sensorimotor Connectivity following Complete Cervical Spinal Cord Injury: A Prospective Resting-State fMRI Study by Oni-Orisan, Akinwunmi, Kaushal, Mayank, Li, Wenjun, Leschke, Jack, Ward, B Douglas, Vedantam, Aditya, Kalinosky, Benjamin, Budde, Matthew D, Schmit, Brian D, Li, Shi-Jiang, Muqeet, Vaishnavi, Kurpad, Shekar N

“…Functional magnetic resonance imaging (fMRI) studies have demonstrated alterations during task-induced brain activation in spinal cord injury (SCI) patients…”
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Evaluation of Whole-Brain Resting-State Functional Connectivity in Spinal Cord Injury: A Large-Scale Network Analysis Using Network-Based Statistic by Kaushal, Mayank, Oni-Orisan, Akinwunmi, Chen, Gang, Li, Wenjun, Leschke, Jack, Ward, B Douglas, Kalinosky, Benjamin, Budde, Matthew D, Schmit, Brian D, Li, Shi-Jiang, Muqeet, Vaishnavi, Kurpad, Shekar N

“…Large-scale network analysis characterizes the brain as a complex network of nodes and edges to evaluate functional connectivity patterns. The utility of…”
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Ex vivo diffusion tensor imaging of spinal cord injury in rats of varying degrees of severity by Jirjis, Michael B, Kurpad, Shekar N, Schmit, Brian D

“…The aim of this study was to characterize magnetic resonance diffusion tensor imaging (DTI) in proximal regions of the spinal cord following a thoracic spinal…”
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Clinical Correlates of High Cervical Fractional Anisotropy in Acute Cervical Spinal Cord Injury by Vedantam, Aditya, Eckardt, Gerald, Wang, Marjorie C, Schmit, Brian D, Kurpad, Shekar N

“…Objective Fractional anisotropy (FA) of the high cervical cord (C1-C2), rostral to the injury site, correlates with upper limb function in patients with…”
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Acute death of astrocytes in blast-exposed rat organotypic hippocampal slice cultures by Miller, Anna P, Shah, Alok S, Aperi, Brandy V, Kurpad, Shekar N, Stemper, Brian D, Glavaski-Joksimovic, Aleksandra

“…Blast traumatic brain injury (bTBI) affects civilians, soldiers, and veterans worldwide and presents significant health concerns. The mechanisms of…”
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Diffusion Tensor Imaging Correlates with Short-Term Myelopathy Outcome in Patients with Cervical Spondylotic Myelopathy by Vedantam, Aditya, MD, Rao, Avinash, BS, Kurpad, Shekar N., MD, PhD, Jirjis, Michael B., PhD, Eckardt, Gerald, MD, Schmit, Brian D., PhD, Wang, Marjorie C., MD, MPH

“…Highlights • Fractional anisotropy correlated with preoperative mJOA score • Fractional anisotropy correlates with 3 month change in mJOA score • These metrics…”
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Spinal Diffusion Tensor Imaging in Evaluation of Preoperative and Postoperative Severity of Cervical Spondylotic Myelopathy: Systematic Review of Literature by Rindler, Rima S., Chokshi, Falgun H., Malcolm, James G., Eshraghi, Sheila R., Mossa-Basha, Mahmud, Chu, Jason K., Kurpad, Shekar N., Ahmad, Faiz U.

“…Diffusion tensor imaging (DTI) is increasingly investigated as a potential diagnostic and prognostic tool for symptomatic degenerative cervical pathology;…”
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Imaging and Electrophysiology for Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 9] by Martin, Allan R., Tetreault, Lindsay, Nouri, Aria, Curt, Armin, Freund, Patrick, Rahimi-Movaghar, Vafa, Wilson, Jefferson R., Fehlings, Michael G., Kwon, Brian K., Harrop, James S., Davies, Benjamin M., Kotter, Mark R. N., Guest, James D., Aarabi, Bizhan, Kurpad, Shekar N

“…Study Design Narrative review. Objective The current review aimed to describe the role of existing techniques and emerging methods of imaging and…”
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Characterization and limitations of diffusion tensor imaging metrics in the cervical spinal cord in neurologically intact subjects by Vedantam, Aditya, Jirjis, Michael B., Schmit, Brian D., Wang, Marjorie C., Ulmer, John L., Kurpad, Shekar N.

“…Purpose To characterize diffusion tensor imaging (DTI) metrics across all levels of the cervical spinal cord (CSC) and to study the impact of age and signal…”
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RE-CODE DCM (REsearch Objectives and Common Data Elements for Degenerative Cervical Myelopathy): A Consensus Process to Improve Research Efficiency in DCM, Through Establishment of a Standardized Dataset for Clinical Research and the Definition of the Research Priorities by Davies, Benjamin M., Khan, Danyal Z., Mowforth, Oliver D., McNair, Angus G. K., Gronlund, Toto, Kolias, Angelos G., Tetreault, Lindsay, Starkey, Michelle L., Sadler, Iwan, Sarewitz, Ellen, Houlton, Delphine, Carter, Julia, Kalsi-Ryan, Sukhvinder, Aarabi, Bizhan, Kwon, Brian K., Kurpad, Shekar N., Harrop, James, Wilson, Jefferson R., Grossman, Robert, Curt, Armin, Fehlings, Michael G., Kotter, Mark R. N.

“…Study Design: Mixed-method consensus process. Objectives: Degenerative cervical myelopathy (DCM) is a common and disabling condition that arises when…”
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Lived experience-centred word clouds may improve research uncertainty gathering in priority setting partnerships by Mowforth, Oliver D, Burn, Lance, Khan, Danyal Z, Yang, Xiaoyu, Stacpoole, Sybil R L, Gronlund, Toto, Tetreault, Lindsay, Kalsi-Ryan, Sukhvinder, Starkey, Michelle L, Sadler, Iwan, Sarewitz, Ellen, Houlton, Delphine, Carter, Julia, Howard, Paige, Rahimi-Movaghar, Vafa, Guest, James D, Aarabi, Bizhan, Kwon, Brian K, Kurpad, Shekar N, Harrop, James, Wilson, Jefferson R, Grossman, Robert, Smith, Emma K, McNair, Angus, Fehlings, Michael G, Kotter, Mark R N, Davies, Benjamin M

“…AO Spine RECODE-DCM was a multi-stakeholder priority setting partnership (PSP) to define the top ten research priorities for degenerative cervical myelopathy…”
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Optimizing the Application of Surgery for Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 10] by Rodrigues-Pinto, Ricardo, Montenegro, Thiago S., Davies, Benjamin M., Kato, So, Kawaguchi, Yoshiharu, Ito, Manabu, Zileli, Mehmet, Kwon, Brian K., Fehlings, Michael G., Koljonen, Paul A., Kurpad, Shekar N., Guest, James D., Aarabi, Bizhan, Rahimi-Movaghar, Vafa, Wilson, Jefferson R., Kotter, Mark R. N., Harrop, James S.

“…Study Design Literature Review (Narrative). Objective To introduce the number 10 research priority for Degenerative Cervical Myelopathy: Individualizing…”
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Are Lumbar Fusion Guidelines Followed? A Survey of North American Spine Surgeons by Montenegro, Thiago S., Elia, Christopher, Hines, Kevin, Buser, Zorica, Wilson, Jefferson, Ghogawala, Zoher, Kurpad, Shekar N., Sciubba, Daniel M., Harrop, James S.

“…Objective To evaluate the use of guidelines for lumbar spine fusions among spine surgeons in North America. Methods An anonymous survey was electronically sent…”
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Optimizing Filter-Probe Diffusion Weighting in the Rat Spinal Cord for Human Translation by Budde, Matthew D, Skinner, Nathan P, Muftuler, L Tugan, Schmit, Brian D, Kurpad, Shekar N

“…Diffusion tensor imaging (DTI) is a promising biomarker of spinal cord injury (SCI). In the acute aftermath, DTI in SCI animal models consistently demonstrates…”
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Behavioral Outcomes Differ between Rotational Acceleration and Blast Mechanisms of Mild Traumatic Brain Injury by Stemper, Brian D, Shah, Alok S, Budde, Matthew D, Olsen, Christopher M, Glavaski-Joksimovic, Aleksandra, Kurpad, Shekar N, McCrea, Michael, Pintar, Frank A

“…Mild traumatic brain injury (mTBI) can result from a number of mechanisms, including blunt impact, head rotational acceleration, exposure to blast, and…”
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Mortality in ASIA Impairment Scale grade A to D Patients With Odontoid Fracture and Magnetic Resonance Imaging Evidence of Spinal Cord Injury by Aarabi, Bizhan, Neal, Christopher J, Hersh, David S, Harrop, James S, Fehlings, Michael G, Toups, Elizabeth G, Guest, James D, Ugiliweneza, Beatrice, Akhtar-Danesh, Noori, Kurpad, Shekar N, Grossman, Robert G

“…Odontoid fractures are common, often presenting in the elderly after a fall and infrequently associated with traumatic spinal cord injury (tSCI). The goal of…”
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High-resolution in vivo diffusion tensor imaging of the injured cat spinal cord using self-navigated, interleaved, variable-density spiral acquisition (SNAILS-DTI) by Ellingson, Benjamin M, Sulaiman, Olawale, Kurpad, Shekar N

“…Abstract Diffusion tensor magnetic resonance imaging (DTI) is useful for studying the microstructural changes in the spinal cord following traumatic injury;…”
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Editorial. Improvements to the manufacturing process for generation of Schwann cells: from laboratory to clinical translation by Kaushal, Mayank, Kurpad, Shekar N

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Development and validation of osteoligamentous lumbar spine under complex loading conditions: A step towards patient-specific modeling by Umale, Sagar, Yoganandan, Narayan, Kurpad, Shekar N.

“…Finite-element models are used to investigate the biomechanics of normal, diseased and surgically fused spines. Generally, nominal spine geometries are used to…”
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