Search Results - "Kurowski, Agata"

Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst by Le Bin, Gloryn Chia, Muñoz-Descalzo, Silvia, Kurowski, Agata, Leitch, Harry, Lou, Xinghua, Mansfield, William, Etienne-Dumeau, Charles, Grabole, Nils, Mulas, Carla, Niwa, Hitoshi, Hadjantonakis, Anna-Katerina, Nichols, Jennifer

“…The transcription factor Oct4 is required in vitro for establishment and maintenance of embryonic stem cells and for reprogramming somatic cells to…”
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The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate by Blanco, Sandra, Kurowski, Agata, Nichols, Jennifer, Watt, Fiona M, Benitah, Salvador Aznar, Frye, Michaela

“…Homeostasis of most adult tissues is maintained by balancing stem cell self-renewal and differentiation, but whether post-transcriptional mechanisms can…”
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nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability by Hussain, Shobbir, Benavente, Sandra Blanco, Nascimento, Elisabete, Dragoni, Ilaria, Kurowski, Agata, Gillich, Astrid, Humphreys, Peter, Frye, Michaela

“…Myc-induced SUN domain-containing protein (Misu or NSun2) is a nucleolar RNA methyltransferase important for c-Myc-induced proliferation in skin, but the…”
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insideOutside: an accessible algorithm for classifying interior and exterior points, with applications in embryology by Strawbridge, Stanley E, Kurowski, Agata, Corujo-Simon, Elena, Fletcher, Alastair N, Nichols, Jennifer, Fletcher, Alexander G

“…A crucial aspect of embryology is relating the position of individual cells to the broader geometry of the embryo. A classic example of this is the first…”
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Genomic gain of 5p15 leads to over-expression of Misu (NSUN2) in breast cancer by Frye, Michaela, Dragoni, Ilaria, Chin, Suet-Feung, Spiteri, Immaculada, Kurowski, Agata, Provenzano, Elena, Green, Andrew, Ellis, Ian O, Grimmer, Donna, Teschendorff, Andrew, Zouboulis, Christos C, Caldas, Carlos, Watt, Fiona M

“…Abstract We have examined expression of the Myc target gene Misu (NSUN2) in breast cancer. There was extensive copy number gain, and increased mRNA and protein…”
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FGFR1 regulates trophectoderm development and facilitates blastocyst implantation by Kurowski, Agata, Molotkov, Andrei, Soriano, Philippe

“…FGF signaling plays important roles in many aspects of mammalian development. Fgfr1-/- and Fgfr1-/-Fgfr2-/- mouse embryos on a 129S4 co-isogenic background…”
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OCT4 induces embryonic pluripotency via STAT3 signaling and metabolic mechanisms by Stirparo, Giuliano G., Kurowski, Agata, Yanagida, Ayaka, Bates, Lawrence E., Strawbridge, Stanley E., Hladkou, Siarhei, Stuart, Hannah T., Boroviak, Thorsten E., Silva, Jose C. R., Nichols, Jennifer

“…OCT4 is a fundamental component of the molecular circuitry governing pluripotency in vivo and in vitro. To determine how OCT4 establishes and protects the…”
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Selective Inhibitors of Autophagy Reveal New Link between the Cell Cycle and Autophagy and Lead to Discovery of Novel Synergistic Drug Combinations by Sung, Kisa, Kurowski, Agata, Lansiquot, Carisse, Wan, Kanny K., Patnaik, Samarjit, Walsh, Martin J., Lazarus, Michael B.

“…Autophagy is a conserved metabolic pathway that is central to many diseases. Recently, there has been a lot of interest in targeting autophagy with small…”
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Mechanistic insights into chromosome-wide silencing in X inactivation by Arthold, Susanne, Kurowski, Agata, Wutz, Anton

“…In mammals, one of the two X chromosomes in female cells is transcriptionally silenced for dosage compensation between the sexes. Chromosome-wide silencing is…”
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Mechanistic insights into chromosome-wide silencing in X inactivation: Special 50th Anniversary Issue on X-inactivation by ARTHOLD, Susanne, KUROWSKI, Agata, WUTZ, Anton

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The RNA-Methyltransferase Misu (NSun2) Poises Epidermal Stem Cells to Differentiate: e1002403 by Blanco, Sandra, Kurowski, Agata, Nichols, Jennifer, Watt, Fiona M, Benitah, Salvador Aznar, Frye, Michaela

“…Homeostasis of most adult tissues is maintained by balancing stem cell self-renewal and differentiation, but whether post-transcriptional mechanisms can…”
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