Search Results - "Kurosh Kalantar"
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The Effects of Type 2 Diabetes Mellitus on Organ Metabolism and the Immune System
Published in Frontiers in immunology (22-07-2020)“…Metabolic abnormalities such as dyslipidemia, hyperinsulinemia, or insulin resistance and obesity play key roles in the induction and progression of type 2…”
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Immune responses in mildly versus critically ill COVID-19 patients
Published in Frontiers in immunology (30-01-2023)“…The current coronavirus pandemic (COVID-19), caused by SARS-CoV-2, has had devastating effects on the global health and economic system. The cellular and…”
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3
Correlation between IL-28 polymorphism and spontaneous clearance in HCV patients: systematic review and meta-analysis
Published in Archives of virology (01-09-2021)“…Hepatitis C virus (HCV) is a serious global health issue. Nearly 20% of HCV patients spontaneously clear the virus. While some studies have shown an…”
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The role of FOXP3 rs3761548 and rs2294021 polymorphisms in pediatrics acute lymphoblastic leukemia: association with risk and response to therapy
Published in Molecular biology reports (01-02-2021)“…FOXP3 X-linked gene has crucial roles in the development and function of regulatory T cells. We investigated the association of FOXP3 rs3761548, rs3761549 and…”
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The effects of killer cell immunoglobulin-like receptor (KIR) genes on susceptibility to severe COVID-19 in the Iranian population
Published in BMC immunology (28-06-2024)“…Variations in the innate and adaptive immune response systems are linked to variations in the severity of COVID-19. Natural killer cell (NK) function is…”
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Targeting TRIM29 As a Negative Regulator of CAR-NK Cell Effector Function to Improve Antitumor Efficacy of these Cells: A Perspective
Published in Current molecular medicine (01-01-2024)“…Natural killer (NK) cells are among the most important cells in innate immune defense. In contrast to T cells, the effector function of NK cells does not…”
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Comparison of the clinical features and outcome of children with hemophagocytic lymphohistiocytosis (HLH) secondary to visceral leishmaniasis and primary HLH: a single-center study
Published in BMC infectious diseases (02-08-2021)“…Abstract Background Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive inflammation. We aimed to describe the clinical and laboratory findings…”
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Anti-inflammatory activity of Echium amoenum extract on macrophages mediated by inhibition of inflammatory mediators and cytokines expression
Published in Research in pharmaceutical sciences (01-01-2018)“…(Boraginaceae) is an important remedy used for various illnesses. In this study, we investigated the anti-inflammatory effects of in the J774.1A macrophage…”
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Decreased levels of interleukin 27 in the serum of vitiligo patients
Published in Anais brasileiros de dermatología (01-09-2020)“…Vitiligo is a common skin disorder in which melanocytes are destroyed by auto-reactive immune responses. The loss of melanocytes results in the appearance of…”
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Alterations in metabolic pathways: a bridge between aging and weaker innate immune response
Published in Frontiers in aging (05-03-2024)“…Aging is a time-dependent progressive physiological process, which results in impaired immune system function. Age-related changes in immune function increase…”
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Decreased serum levels of IL-27and IL-35 in patients with Graves disease
Published in Archives of Endocrinology and Metabolism (18-05-2021)“…Graves' disease (GD) is an autoimmune disease causing the overproduction of the thyroid hormone from thyroid gland. This disease is mainly the result of the…”
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12
Variations in IL-22, IL-27 and IL-35 serum levels in untreated and treated hepatitis C patients
Published in European cytokine network (01-12-2020)“…Hepatitis C virus (HCV) is the leading cause of chronic liver diseases including hepatic fibrosis, cirrhosis, and hepatocellular carcinoma. We aimed to assess…”
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13
Targeting T Cell Metabolism as a Novel Approach for Treatment of MS: With a Focus on PFKFB3 Inhibitors
Published in Endocrine, metabolic & immune disorders drug targets (01-01-2023)“…Multiple sclerosis (MS) is one of the organ-specific autoimmune diseases in which immune cells invade the neurons in the central nervous system (CNS) due to…”
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Interleukin-27 gene variant rs153109 is associated with enhanced cytokine serum levels and susceptibility to Behçet's disease in the Iranian population
Published in European cytokine network (Montrouge) (01-12-2020)“…Behcet’s disease (BD) is a systemic vasculitis, characterized by recurrent oral aphthous, genital ulcers, ocular lesions, and other organ involvement…”
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Using proteomics as a powerful tool to develop a vaccine against Mediterranean visceral leishmaniasis
Published in Journal of parasitic diseases (01-06-2018)“…Visceral leishmaniasis (VL) is a tropical infectious disease, which is called Mediterranean visceral leishmaniasis (MVL) in the Mediterranean area. In spite of…”
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Seroepidemiological Study of Toxoplasma gondii Infection among Psychiatric Patients in Mashhad, Northeast of Iran
Published in Iranian journal of parasitology (01-01-2017)“…Psychiatric patients have an increased risk of some infections like toxoplasmosis. Investigations on infection among psychiatric patients have been limited in…”
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Comparison of the Antibody Responses Following Vaccination with AstraZeneca and Sinopharm
Published in Iranian journal of immunology (01-09-2022)“…Vaccines are the most effective way to prevent Coronavirus 2 severe acute respiratory syndrome (SARS-CoV-2). To compare the antibody response of healthy…”
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Pro-inflammatory Effects of Influenza Type A Virus PB1-F2 Protein-derived Peptide in Lipopolysaccharide-treated Macrophages
Published in Iranian journal of allergy, asthma, and immunology (17-05-2020)“…Influenza A virus (IAV) has the potential to cause pandemics with considerable health and socio-economic burdens. A viral protein, polymerase basic 1- frame2…”
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The frequency of CD4+ and CD8+ circulating T stem cell memory in type 1 diabetes
Published in Immunity, Inflammation and Disease (01-10-2022)“…Introduction The frequencies and functions of T stem cell memory (TSCM) subsets vary in autoimmune diseases. We evaluated the frequencies of CD4+ and CD8+ TSCM…”
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20
The Seroprevalence of Human Cystic Echinococcosis in Iran: A Systematic Review and Meta-Analysis Study
Published in Journal of Parasitology Research (2016)“…Human cystic echinococcosis (HCE), a zoonotic infection of the larval stage of Echinococcus granulosus, has high effect on public health in human population…”
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