Search Results - "Kurosawa, Sumire"
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Molecular Basis for Enzymatic Aziridine Formation via Sulfate Elimination
Published in Journal of the American Chemical Society (07-09-2022)“…Natural products containing an aziridine ring, such as mitomycin C and azinomycin B, exhibit antitumor activities by alkylating DNA via their aziridine rings;…”
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Mechanisms of Sugar Aminotransferase-like Enzymes to Synthesize Stereoisomers of Non-proteinogenic Amino Acids in Natural Product Biosynthesis
Published in ACS chemical biology (17-02-2023)“…(2,6)-Diamino-(5,7)-dihydroxyheptanoic acid (DADH), a non-proteinogenic amino acid, is converted to 1-azabicyclo[3.1.0]hexane ring-containing amino acids that…”
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Major intraoperative bleeding and drastic change in circulatory dynamics in a pregnant patient with metastatic pheochromocytoma: a case report
Published in JA clinical reports (22-02-2022)“…Background Metastatic pheochromocytoma in the spine is a very rare complication during pregnancy. We report anesthesia in a pregnant woman for resection of an…”
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Immunosuppressive effect of a non-proteinogenic amino acid from Streptomyces through inhibiting allogeneic T cell proliferation
Published in Bioscience, biotechnology, and biochemistry (03-06-2019)“…The immunosuppressive activity of myriocin (ISP-1), a lead compound of fingolimod (FTY720), is derived from its 2-amino-1,3-propandiol structure. A…”
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Structural basis for potent inhibition of d-amino acid oxidase by thiophene carboxylic acids
Published in European journal of medicinal chemistry (05-11-2018)“…A series of thiophene-2-carboxylic acids and thiophene-3-carboxylic acids were identified as a new class of DAO inhibitors. Structure-activity relationship…”
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