Search Results - "Kurosaka, Satoshi"
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Unusual semi‐extractability as a hallmark of nuclear body‐associated architectural noncoding RNAs
Published in The EMBO journal (15-05-2017)“…NEAT1_2 long noncoding RNA (lncRNA) is the molecular scaffold of paraspeckle nuclear bodies. Here, we report an improved RNA extraction method: extensive…”
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Structural, super-resolution microscopy analysis of paraspeckle nuclear body organization
Published in The Journal of cell biology (26-09-2016)“…Paraspeckles are nuclear bodies built on the long noncoding RNA Neat1, which regulates a variety of physiological processes including cancer progression and…”
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3
Different translation dynamics of β- and γ-actin regulates cell migration
Published in eLife (24-06-2021)“…β- and γ-cytoplasmic actins are ubiquitously expressed in every cell type and are nearly identical at the amino acid level but play vastly different roles in…”
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Effects of exposure to methylglyoxal on sperm motility and embryonic development after fertilization in mice
Published in Journal of Reproduction and Development (2021)“…Methylglyoxal (MG) is a precursor for the generation of endogenous advanced glycation end-products involved in various diseases, including infertility. The…”
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Diverse functions of homologous actin isoforms are defined by their nucleotide, rather than their amino acid sequence
Published in eLife (15-12-2017)“…β- and γ-cytoplasmic actin are nearly indistinguishable in their amino acid sequence, but are encoded by different genes that play non-redundant biological…”
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Cell biology of embryonic migration
Published in Birth defects research. Part C. Embryo today (01-06-2008)“…Cell migration is an evolutionarily conserved mechanism that underlies the development and functioning of uni‐ and multicellular organisms and takes place in…”
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Species-specific formation of paraspeckles in intestinal epithelium revealed by characterization of NEAT1 in naked mole-rat
Published in RNA (Cambridge) (01-08-2022)“…Paraspeckles are mammalian-specific nuclear bodies built on the long noncoding RNA The molecular mechanisms of paraspeckle formation have been mainly studied…”
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Signs of biological activities of 28,000-year-old mammoth nuclei in mouse oocytes visualized by live-cell imaging
Published in Scientific reports (11-03-2019)“…The 28,000-year-old remains of a woolly mammoth, named ‘Yuka’, were found in Siberian permafrost. Here we recovered the less-damaged nucleus-like structures…”
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Conditional Tek promoter-driven deletion of arginyltransferase in the germ line causes defects in gametogenesis and early embryonic lethality in mice
Published in PloS one (05-11-2009)“…Posttranslational protein arginylation mediated by Ate1 is essential for cardiovascular development, actin cytoskeleton functioning, and cell migration. Ate1…”
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10
Arginylation-dependent neural crest cell migration is essential for mouse development
Published in PLoS genetics (01-03-2010)“…Coordinated cell migration during development is crucial for morphogenesis and largely relies on cells of the neural crest lineage that migrate over long…”
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Pluripotent Lineage Definition in Bovine Embryos by Oct4 Transcript Localization
Published in Biology of reproduction (01-11-2004)“…The POU-domain transcription factor Pou5f1 (Oct4) is restricted to pluripotent embryonic cells and the germ line of the mouse and is required for the…”
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Translocated in liposarcoma regulates the distribution and function of mammalian enabled, a modulator of actin dynamics
Published in The FEBS journal (01-04-2016)“…Translocated in liposarcoma/fused in sarcoma (TLS/FUS) is an RNA‐binding protein that regulates the splicing pattern of mRNA transcripts and is known to cause…”
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Quantitative Monitoring of Pluripotency Gene Activation after Somatic Cloning in Cattle
Published in Biology of reproduction (01-06-2007)“…The development of somatic cell nuclear transfer (SCNT) embryos critically depends on appropriate reprogramming and expression of pluripotency genes, such as…”
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14
Androgenetic Embryonic Stem Cells Form Neural Progenitor Cells In Vivo and In Vitro
Published in Stem cells (Dayton, Ohio) (01-06-2008)“…Uniparental zygotes with two paternal (androgenetic [AG]) or two maternal (gynogenetic [GG]; parthenogenetic [PG]) genomes are not able to develop into viable…”
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Dependence of DNA Synthesis and In Vitro Development of Bovine Nuclear Transfer Embryos on the Stage of the Cell Cycle of Donor Cells and Recipient Cytoplasts
Published in Biology of reproduction (01-08-2002)“…The effect of the stage of the cell cycle of donor cells and recipient cytoplasts on the timing of DNA replication and the developmental ability in vitro of…”
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Pluripotent Lineage Definition in Bovine Embryos by Oct4 Transcript Localization1
Published in Biology of reproduction (01-11-2004)“…The POU-domain transcription factor Pou5f1 (Oct4) is restricted to pluripotent embryonic cells and the germ line of the mouse and is required for the…”
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Differential reprogramming of somatic cell nuclei after transfer into mouse cleavage stage blastomeres
Published in Reproduction (Cambridge, England) (01-05-2005)“…Mammalian somatic cell cloning requires factors specific to the oocyte for reprogramming to succeed. This does not exclude that reprogramming continues during…”
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Rapid and dynamic arginylation of the leading edge β‐actin is required for cell migration
Published in Traffic (Copenhagen, Denmark) (01-04-2018)“…This study demonstrates that β‐actin arginylation occurs primarily at the very edge of migrating cells, that it responds rapidly to cell stimulation inducing…”
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Functional Differences between β- and γ-Actin: From Translation Dynamics to Amino Acid Changes
Published in Biophysical journal (12-02-2021)Get full text
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In vivo and in vitro differentiation of uniparental embryonic stem cells into hematopoietic and neural cell types
Published in Organogenesis (01-01-2008)“…The biological role of genomic imprinting in adult tissue is central to the consideration of transplanting uniparental embryonic stem (ES) cell-derived…”
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