Search Results - "Kurosaka, Hiroshi"

The Roles of Hedgehog Signaling in Upper Lip Formation by Kurosaka, Hiroshi

“…Craniofacial development consists of a highly complex sequence of the orchestrated growth and fusion of facial processes. It is also known that craniofacial…”
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Comprehensive Orthodontic Treatment of a Patient With Prader–Willi Syndrome by Uemura, Yume, Oka, Ayaka, Kurosaka, Hiroshi, Yamashiro, Takashi

“…Prader–Willi syndrome (PWS) is a rare genetic disorder caused by a defect in paternally expressed genes in the 15q11-q13 region. Prader–Willi syndrome affects…”
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The Association Between Runx Signaling and Craniofacial Development and Disease by Yamashiro, Takashi, Kurosaka, Hiroshi, Inubush, Toshihiro

“…Purpose of Review The Runx family genes ( Runx1, Runx2, Runx3 , and Cbfb ) are important transcriptional regulators in the development of various tissues. We…”
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Rdh10 loss-of-function and perturbed retinoid signaling underlies the etiology of choanal atresia by Kurosaka, Hiroshi, Wang, Qi, Sandell, Lisa, Yamashiro, Takashi, Trainor, Paul A

“…Craniofacial development is a complex process that involves sequential growth and fusion of the facial prominences. When these processes fail, congenital…”
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The roles of JAK2/STAT3 signaling in fusion of the secondary palate by Yoshida, Naoki, Inubushi, Toshihiro, Hirose, Takumi, Aoyama, Gozo, Kurosaka, Hiroshi, Yamashiro, Takashi

“…ABSTRACT Cleft palate has a multifactorial etiology. In palatal fusion, the contacting medial edge epithelium (MEE) forms the epithelial seam, which is…”
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Perturbed development of cranial neural crest cells in association with reduced sonic hedgehog signaling underlies the pathogenesis of retinoic-acid-induced cleft palate by Wang, Qi, Kurosaka, Hiroshi, Kikuchi, Masataka, Nakaya, Akihiro, Trainor, Paul A, Yamashiro, Takashi

“…Cleft palate (CP) is one of the most common congenital craniofacial anomalies in humans and can be caused by either single or multiple genetic and…”
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Multidisciplinary Approach for Treating Malocclusion of Patient With Basal Cell Nevus Syndrome: A Case Report by Inoue, Sayuri, Kurosaka, Hiroshi, Lee, Donghoon, Yamashiro, Takashi

“…Basal cell nevus syndrome (BCNS) is a rare genetic disorder that can be caused by mutation of multiple genes, including PTCH1, PTCH2, and SUFU, in an autosomal…”
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The cell surface hyaluronidase TMEM2 plays an essential role in mouse neural crest cell development and survival by Inubushi, Toshihiro, Nakanishi, Yuichiro, Abe, Makoto, Takahata, Yoshifumi, Nishimura, Riko, Kurosaka, Hiroshi, Irie, Fumitoshi, Yamashiro, Takashi, Yamaguchi, Yu

“…Hyaluronan (HA) is a major extracellular matrix component whose tissue levels are dynamically regulated during embryonic development. Although the synthesis of…”
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Synergistic role of retinoic acid signaling and Gata3 during primitive choanae formation by Kurosaka, Hiroshi, Mushiake, Jin, Saha, Mithun, Wu, Yanran, Wang, Qi, Kikuchi, Masataka, Nakaya, Akihiro, Yamamoto, Sayuri, Inubushi, Toshihiro, Koga, Satoshi, Sandell, Lisa L, Trainor, Paul A, Yamashiro, Takashi

“…Abstract Developmental defects of primitive choanae, an anatomical path to connect the embryonic nasal and oral cavity, result in disorders called choanal…”
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Cranial nerve development requires co-ordinated Shh and canonical Wnt signaling by Kurosaka, Hiroshi, Trainor, Paul A, Leroux-Berger, Margot, Iulianella, Angelo

“…Cranial nerves govern sensory and motor information exchange between the brain and tissues of the head and neck. The cranial nerves are derived from two…”
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Runx1 mediates the development of the granular convoluted tubules in the submandibular glands by Ono Minagi, Hitomi, Sarper, Safiye Esra, Kurosaka, Hiroshi, Kuremoto, Koh-Ichi, Taniuchi, Ichiro, Sakai, Takayoshi, Yamashiro, Takashi

“…The mouse granular convoluted tubules (GCTs), which are only located in the submandibular gland (SMG) are known to develop and maintain their structure in an…”
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Topical application of lithium chloride on the pulp induces dentin regeneration by Ishimoto, Kazuya, Hayano, Satoru, Yanagita, Takeshi, Kurosaka, Hiroshi, Kawanabe, Noriaki, Itoh, Shinsuke, Ono, Mitsuaki, Kuboki, Takuo, Kamioka, Hiroshi, Yamashiro, Takashi

“…We herein describe a novel procedure for dentin regeneration that mimics the biological processes of tooth development in nature. The canonical Wnt signaling…”
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Development of dentition: From initiation to occlusion and related diseases by Kurosaka, Hiroshi, Itoh, Shinsuke, Morita, Chisato, Tsujimoto, Takayuki, Murata, Yuka, Inubushi, Toshihiro, Yamashiro, Takashi

“…The development of dentition begins in the embryonic oral cavity and progresses in the branchial arches and alveolar bone. Continuous cellular and molecular…”
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Ventral neural patterning in the absence of a Shh activity gradient from the floorplate by Iulianella, Angelo, Sakai, Daisuke, Kurosaka, Hiroshi, Trainor, Paul A.

“…Background: Vertebrate spinal cord development requires Sonic Hedgehog (Shh) signaling from the floorplate and notochord, where it is thought to act in…”
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Fork‐shaped mandibular incisors as a novel phenotype of LRP5‐associated disorder by Yamada, Mamiko, Kubota, Kazumi, Uchida, Atsuro, Yagihashi, Tatsuhiko, Kawasaki, Masahito, Suzuki, Hisato, Uehara, Tomoko, Takenouchi, Toshiki, Kurosaka, Hiroshi, Kosaki, Kenjiro

“…The LRP5 gene encodes a Wnt signaling receptor to which Wnt binds directly. In humans, pathogenic monoallelic variants in LRP5 have been associated with…”
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Intracellular and Intercellular Gene Regulatory Network Inference From Time-Course Individual RNA-Seq by Kashima, Makoto, Shida, Yuki, Yamashiro, Takashi, Hirata, Hiromi, Kurosaka, Hiroshi

“…Gene regulatory network (GRN) inference is an effective approach to understand the molecular mechanisms underlying biological events. Generally, GRN inference…”
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Runx1-Stat3 signaling regulates the epithelial stem cells in continuously growing incisors by Sarper, Safiye E., Inubushi, Toshihiro, Kurosaka, Hiroshi, Ono Minagi, Hitomi, Kuremoto, Koh-ichi, Sakai, Takayoshi, Taniuchi, Ichiro, Yamashiro, Takashi

“…Rodent incisors grow permanently and the homeostasis of enamel production is maintained by a continuous supply of epithelial progenitors from putative stem…”
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Ras signaling and RREB1 are required for the dissociation of medial edge epithelial cells in murine palatogenesis by Inubushi, Toshihiro, Fujiwara, Ayaka, Hirose, Takumi, Aoyama, Gozo, Uchihashi, Toshihiro, Yoshida, Naoki, Shiraishi, Yuki, Usami, Yu, Kurosaka, Hiroshi, Toyosawa, Satoru, Tanaka, Susumu, Watabe, Tetsuro, Kogo, Mikihiko, Yamashiro, Takashi

“…Cleft palate is one of the major congenital craniofacial birth defects. The etiology underlying the pathogenesis of cleft palate has yet to be fully…”
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A quantitative method for defining high-arched palate using the Tcof1+/− mutant mouse as a model by Conley, Zachary R., Hague, Molly, Kurosaka, Hiroshi, Dixon, Jill, Dixon, Michael J., Trainor, Paul A.

“…The palate functions as the roof of the mouth in mammals, separating the oral and nasal cavities. Its complex embryonic development and assembly poses unique…”
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Orthodontic-Surgical Approach for Treating Skeletal Class III Malocclusion With Severe Maxillary Deficiency in Isolated Cleft Palate by Nakatsugawa, Kohei, Kurosaka, Hiroshi, Mihara, Kiyomi, Tanaka, Susumu, Aikawa, Tomonao, Kogo, Mikihiko, Yamashiro, Takashi

“…Orthodontic treatment in patients with orofacial cleft such as cleft lip and palate or isolated cleft palate is challenging, especially when the patients…”
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