Search Results - "Kuroo, M"

Introduction: aging research comes of age by Kuroo, M

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Activation of Na +-H + Antiporter (NHE-1) gene expression during growth, hypertrophy and proliferation of the rabbit cardiovascular system by Takewaki, Syin-ichi, Kuro-o, Makoto, Hiroi, Yukio, Yamazaki, Tsutomu, Noguchi, Tsuyoshi, Miyagishi, Akira, Nakahara, Ken-ichi, Aikawa, Masanori, Manabe, Ichiro, Yazaki, Yoshio, Nagai, Ryozo

“…S.-I. Takewaki, M. Kuro-o, Y. Hiroi, T. Yamazaki, T. Noguchi, A. Miyagishi, K.-I. Nakahara, M. Aikawa, I. Manabe, Y. Yazaki and R. Nagai, Activation of Na +-H…”
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The protective role of Klotho gene on vascular endothelium by Saito, Y, Kuroo, M, Nabeshima, Y, Nagai, R

“…Arteriosclerosis caused by aging is recognized to be a crucial risk factor of cardiovascular disease. We recently established Klotho mouse that causes…”
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Mutation of the mouse klotho gene leads to a syndrome resembling ageing by Kuro-o, Makoto, Nabeshima, Yo-ichi, Matsumura, Yutaka, Aizawa, Hiroki, Kawaguchi, Hiroshi, Suga, Tatsuo, Utsugi, Toshihiro, Ohyama, Yoshio, Kurabayashi, Masahiko, Kaname, Tadashi, Kume, Eisuke, Iwasaki, Hitoshi, Iida, Akihiro, Shiraki-Iida, Takako, Nishikawa, Satoshi, Nagai, Ryozo

“…A new gene, termed klotho, has been identified that is involved in the suppression of several ageing phenotypes. A defect in klotho gene expression in the…”
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klotho gene by Saito, Y, Kuroo, M, Nabeshima, Y, Nagai, R

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Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases by Nagai, R, Saito, Y, Ohyama, Y, Aizawa, H, Suga, T, Nakamura, T, Kurabayashi, M, Kuroo, M

“…The human aging process is associated with vascular endothelial dysfunction. However, humoral factors which might protect against endothelial dysfunction…”
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Vascular smooth muscle cells and arteriosclerosis by Nagai, R, Aikawa, M, Kuroo, M, Yazaki, Y

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Development of a novel mouse model for human aging by Kuroo, M

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Human Smooth Muscle Myosin Heavy Chain Isoforms as Molecular Markers for Vascular Development and Atherosclerosis by Aikawa, Masanori, Sivam, Palanisamy Nalla, Kuro-o, Makoto, Kimura, Kenjiro, Nakahara, Ken-ichi, Takewaki, Shun-ichi, Ueda, Makiko, Yamaguchi, Hiroshi, Yazaki, Yoshio, Periasamy, Muthu, Nagai, Ryozo

“…Smooth muscle myosin heavy chains (MHCs) exist in multiple isoforms. Rabbit smooth muscles contain at least three types of MHC isoformsSM1 (204 kD), SM2 (200…”
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Cellular and molecular mechanism of low-turnover osteopenia in the klotho-deficient mouse by Kawaguchi, H, Manabe, N, Chikuda, H, Nakamura, K, Kuroo, M

“…The mouse homozygous for a disruption of the klotho locus (KL-/- or klotho mouse) exhibited multiple pathological conditions resembling human aging. We…”
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cDNA cloning of a myosin heavy chain isoform in embryonic smooth muscle and its expression during vascular development and in arteriosclerosis by Kuro-o, M, Nagai, R, Nakahara, K, Katoh, H, Tsai, R C, Tsuchimochi, H, Yazaki, Y, Ohkubo, A, Takaku, F

“…Adult rabbit smooth muscles contain two types of myosin heavy chain (MHC) isoforms, SM1 and SM2 which are generated through alternative RNA splicing from a…”
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Developmentally regulated expression of vascular smooth muscle myosin heavy chain isoforms by Kuro-o, M, Nagai, R, Tsuchimochi, H, Katoh, H, Yazaki, Y, Ohkubo, A, Takaku, F

“…Two types of smooth muscle myosin heavy chain (MHC) isoforms, SM1 and SM2, were recently identified to have different carboxyl termini (Nagai, R., Kuro-o, M.,…”
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Salt-sensitive hypertension in transgenic mice overexpressing Na+-proton exchanger by KURO-O, M, HANAOKA, K, YAZAKI, Y, NABESHIMA, Y.-I, HIROI, Y, NOGUCHI, T, FUJIMORI, Y, TAKEWAKI, S.-I, HAYASAKA, M, KATOH, H, MIYAGISHI, A, NAGAI, R

“…Essential hypertension is one of the most common diseases that exacerbate the risk of cardiovascular or cerebrovascular attacks. Although the etiology of…”
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Ductus arteriosus : advanced differentiation of smooth muscle cells demonstrated by myosin heavy chain isoform expression in rabbits by HYO-SOO KIM, AIKAWA, M, KIMURA, K, KURO-O, M, NAKAHARA, K.-I, SUZUKI, T, KATOH, H, OKAMOTO, E.-I, YAZAKI, Y, NAGAI, R

“…The closure of the ductus arteriosus (DA) is one of the most striking cardiovascular events that occur at birth. It has been attributed to oxygenation and…”
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Structure and characterization of the 5'-flanking region of the mouse smooth muscle myosin heavy chain (SM1/2) gene by WATANABE, M, SAKOMURA, Y, KURABAYASHI, M, MANABE, I, AIKAWA, M, KURO-O, M, SUZUKI, T, YAZAKI, Y, NAGAI, R

“…We have previously shown that smooth muscle myosin heavy chain isoforms (SMs), including SM1, SM2, and SMemb, are differentially expressed during vascular…”
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Transgenic expression of a novel thymic epithelial cell antigen stimulates abberant development of thymocytes by Takeuchi, T, Kuro-o, M, Miyazawa, H, Ohtsuki, Y, Yamamoto, H

“…We previously reported a novel thymic stromal cell Ag, HS9, as a potent molecule participating in intrathymic T cell development. HS9 Ag is expressed on thymic…”
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Isolation of the Embryonic Form of Smooth Muscle Myosin Heavy Chain (SMemb/NMHC-B) Gene and Characterization of Its 5′-Flanking Region by Manabe, Ichiro, Kurabayashi, Masahiko, Shimomura, Yukio, Kuro-o, Makoto, Watanabe, Noboru, Watanabe, Masafumi, Aikawa, Masanori, Suzuki, Toru, Yazaki, Yoshio, Nagai, Ryozo

“…To examine the molecular mechanisms that regulate the expression of the SMemb/NMHC-B gene, a nonmuscle myosin heavy chain isoform predominantly expressed in…”
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Germ line-restricted, highly repeated DNA sequences and their chromosomal localization in a Japanese hagfish (Eptatretus okinoseanus) by KUBOTA, S, KURO-O, M, MIZUNO, S, KOHNO, S

“…The various species of Japanese hagfish, namely, Eptatretus okinoseanus (types A and B), Eptatretus burgeri and Myxine garmani, are known to eliminate a…”
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Diversity of the synthetic-state smooth-muscle cells proliferating in mechanically and hemodynamically injured rabbit arteries by Okamoto, E, Suzuki, T, Aikawa, M, Imataka, K, Fujii, J, Kuro-o, M, Nakahara, K, Hasegawa, A, Yazaki, Y, Nagai, R

“…Vascular smooth muscles contain at least three types of developmentally regulated myosin heavy-chain (MHC) isoforms; SM1, SM2, and SMemb. By investigating the…”
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Diversity and variability of smooth muscle phenotypes of renal arterioles as revealed by myosin isoform expression by Kimura, Kenjiro, Nagai, Ryozo, Sakai, Tatsuo, Aikawa, Masanori, Kuro-o, Makoto, Kobayashi, Naoto, Shirato, Isao, Inagami, Tadashi, Oshi, Masaya, Suzuki, Naoe, Oba, Shigeyoshi, Mise, Naobumi, Tojo, Akihiro, Hirata, Yasunobu, Goto, Atsuo, Yazaki, Yoshio, Omata, Masao

“…Diversity and variability of smooth muscle phenotypes of renal arterioles as revealed by myosin isoform expression. The contractility and extensibility of…”
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