Search Results - "Kuroki, Hiroaki"

Structure–activity relationships of 44 halogenated compounds for iodotyrosine deiodinase-inhibitory activity by Shimizu, Ryo, Yamaguchi, Masafumi, Uramaru, Naoto, Kuroki, Hiroaki, Ohta, Shigeru, Kitamura, Shigeyuki, Sugihara, Kazumi

“…Abstract The aim of this study was to investigate the possible influence of halogenated compounds on thyroid hormone metabolism via inhibition of iodotyrosine…”
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Characterization of steroid hormone receptor activities in 100 hydroxylated polychlorinated biphenyls, including congeners identified in humans by Takeuchi, Shinji, Shiraishi, Fujio, Kitamura, Shigeyuki, Kuroki, Hiroaki, Jin, Kazuo, Kojima, Hiroyuki

“…Highlights ► We examine hormonal activities of 100 hydroxylated polychlorinated biphenyls. ► We use four assays of estrogen alpha, beta, androgen, and…”
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Thyroid hormonal activity of the flame retardants tetrabromobisphenol A and tetrachlorobisphenol A by Kitamura, Shigeyuki, Jinno, Norimasa, Ohta, Shigeru, Kuroki, Hiroaki, Fujimoto, Nariaki

“…The thyroid hormonal-disrupting activity of the flame retardants tetrabromobisphenol A (TBBPA) and tetrachlorobisphenol A (TCBPA) was examined and compared…”
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Effect of adenosine system in the action of oseltamivir on behavior in mice by Uchiyama, Hidemori, Hiromura, Makoto, Shiratani, Tomonori, Kuroki, Hiroaki, Honda, Sinichiro, Kosako, Kazuhiro, Soeda, Shinji, Inoue, Kazuhide, Toda, Akihisa

“…•Caffeine (10mg/kg) in combination with oseltamivir for 1 day increased ambulation.•Caffeine (30mg/kg) in combination with oseltamivir for 3 days increased…”
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2,3,4,7,8-Pentachlorodibenzofuran is far less potent than 2,3,7,8-tetrachlorodibenzo-p-dioxin in disrupting the pituitary–gonad axis of the rat fetus by Taura, Junki, Takeda, Tomoki, Fujii, Misaki, Hattori, Yukiko, Ishii, Yuji, Kuroki, Hiroaki, Tsukimori, Kiyomi, Uchi, Hiroshi, Furue, Masutaka, Yamada, Hideyuki

“…The effect of 2,3,4,7,8-pentachlorodibenzofuran (PnCDF) on the fetal pituitary–gonad axis was compared with that produced by…”
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Determination of tetrabromobisphenol A in human serum by liquid chromatography–electrospray ionization tandem mass spectrometry by Hayama, Tadashi, Yoshida, Hideyuki, Onimaru, Suzuko, Yonekura, Sayuri, Kuroki, Hiroaki, Todoroki, Kenichiro, Nohta, Hitoshi, Yamaguchi, Masatoshi

“…A method for the determination of tetrabromobisphenol A (TBBPA) in human serum utilizing solid-phase extractions (SPEs) and liquid chromatography (LC) with…”
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The Effect of Maternal Exposure to Dioxins on the Level of Thyroid Hormone in Developing Pups by Hattori, Yukiko, Takeda, Tomoki, Taura, Junki, Kuroki, Hiroaki, Ishii, Yuji, Yamada, Hideyuki

“…Maternal exposure to dioxins causes a number of developmental disorders in the offspring. Previous studies have suggested that lactational exposure to…”
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Effect of Cynaropicrin on 2,3,4,7,8-Pentachlorodibenzofuran-induced Wasting Syndrome and Oxidative Stress by Yamada, Ken-ichi, Ishii, Yuji, Takeda, Tomoki, Kuroki, Hiroaki, Mitoma, Chikage, Uchi, Hiroshi, Furue, Masutaka, Yamada, Hideyuki

“…The effect of cynaropicrin that is the major component of an edible plant, artichoke (Cynara scolymus) on 2,3,4,7,8-pentachlorodibenzofuran (PenCDF)-induced…”
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4-Hydroxy-3,5,3',4'-Tetrachlorobiphenyl Induced Membrane Permeability Transition in Isolated Rat Liver Mitochondria by Fujita, Hirofumi, Okimura, Yuya, Utsumi, Toshihiko, Kitamura, Shigeyuki, Kuroki, Hiroaki, Otsuki, Takemi, Sasaki, Junzo, Kashiwagi, Akihiko, Utsumi, Kozo

“…Although much information about the apoptotic and other detrimental actions of polychlorinated biphenyls (PCBs) has been accumulated, the critical role of…”
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Selectivity of electron-donor- and electron-acceptor-bonded silica packing materials for hydrophobic environmental contaminants in polar and non-polar eluents by Kimata, Kazuhiro, Hosoya, Ken, Kuroki, Hiroaki, Tanaka, Nobuo, Barr, John R., McClure, P.Cheryl, Patterson, Donald G., Jakobsson, Eva, Bergman, Ake

“…Electron-acceptor-bonded stationary phases, 2-(nitrophenyl)-ethylsilyl (NPE) 3-( p-nitrophenoxy)propylsilyl (NPO), and electron-donor-bonded phases,…”
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Elimination of polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) from human blood in the yusho and yu-cheng rice oil poisonings by Ryan, J.J. (Health Protection Branch, Health and Welfare Canada, Ottawa, Canada), Levesque, D, Panopio, L.G, Sun, W.F, Masuda, Y, Kuroki, H

“…The pharmacokinetics of polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) in humans was studied by monitoring the blood concentrations…”
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Metabolism of 2,3′,4′,5-tetrachlorobiphenyl by cytochrome P450 from rats, guinea pigs and hamsters by Koga, Nobuyuki, Kikuichi, Naoko, Kanamaru, Tomoyo, Kuroki, Hiroaki, Matsusue, Kimihiko, Ishida, Chuzo, Ariyoshi, Noritaka, Oguri, Kazuta, Yoshimura, Hidetoshi

“…The metabolism of 2,3′,4′,5-tetrachlorobiphenyl (TCB) was compared using liver microsomes and six isoforms of cytochrome P450 purified from rats, guinea pigs…”
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Thyroid hormone-like and estrogenic activity of hydroxylated PCBs in cell culture by Kitamura, Shigeyuki, Jinno, Norimasa, Suzuki, Tomoharu, Sugihara, Kazumi, Ohta, Shigeru, Kuroki, Hiroaki, Fujimoto, Nariaki

“…The thyroid hormone-disrupting activity of hydroxylated PCBs was examined. 4-Hydroxy-2,2′,3,4′,5,5′-hexachlorobiphenyl (4-OH-2,2′,3,4′,5,5′-HxCB),…”
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Metabolism of 2,3,3',4,4'-pentachlorobiphenyl in hamsters by Koga, Nobuyuki, Kuroki, Hiroaki, Haraguchi, Koichi, Kanamaru, Tomoyo, Kato, Yoshihisa, Kimura, Ryohei

“…The in vivo metabolism of 2,3,3',4,4'-pentachlorobiphenyl (CB105) was studied in hamsters and the effect of cytochrome P450 inducers, phenobarbital (PB) and…”
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Covalent binding of nitroso-sulfonamides to glutathione S-transferase in guinea pigs with delayed type hypersensitivity by Eyanagi, Reiko, Toda, Akihisa, Imoto, Masumi, Uchiyama, Hidemori, Ishii, Yuji, Kuroki, Hiroaki, Kuramoto, Yukako, Soeda, Shinji, Shimeno, Hiroshi

“…Drug induced allergies are believed to be induced by conjugates consisting of biological macromolecules and active metabolites. The present study investigated…”
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The stimulatory effects of caffeine with oseltamivir (Tamiflu ®) on light–dark behavior and open-field behavior in mice by Uchiyama, Hidemori, Toda, Akihisa, Imoto, Masumi, Nishimura, Satoko, Kuroki, Hiroaki, Soeda, Shinji, Shimeno, Hiroshi, Watanabe, Shigenori, Eyanagi, Reiko

“…Abnormal behaviors and death associated with the use of oseltamivir (Tamiflu ®) have emerged as a major issue in influenza patients taking the drug. Here, we…”
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PCB and PCDF Congeners in the Blood and Tissues of Yusho and Yu-Cheng Patients by Masuda, Yoshito, Kuroki, Hiroaki, Haraguchi, Koichi, Nagayama, Junya

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Inductive effect on hepatic enzymes and acute toxicity of individual polychlorinated dibenzofuran congeners in rats by Yoshihara, S, Nagata, K, Yoshimura, H, Kuroki, H, Masuda, Y

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Selective Retention of Hydroxylated PCB Metabolites in Blood by Bergman, Åke, Klasson-Wehler, Eva, Kuroki, Hiroaki

“…Polychlorinated biphenyls (PCBs) are important environmental contaminants, and their toxicity to wildlife and humans are of major concern. PCBs form persistent…”
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A unique change of steroid metabolism in rat liver microsomes induced with highly toxic polychlorinated biphenyl(PCB) and polychlorinated dibenzofuran(PCDF) by Yoshihara, S, Nagata, K, Wada, I, Yoshimura, H, Kuroki, H, Masuda, Y

“…Pretreatments of rats with the highly toxic compounds such as 3,4,5,3',4'-pentachlorobiphenyl(PenCB), and 2,3,7,8-tetrachloro(TCDF) and…”
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