Search Results - "Kuroiwa‐Trzmielina, Joice"

The economic costs of precision medicine for clinical translational research among children with high-risk cancer by Owens, Christopher E. L., Tan, Owen, Kuroiwa-Trzmielina, Joice, Shrestha, Rupendra N., O’Brien, Tracey, Tyrrell, Vanessa, Schofield, Deborah J.

“…Embedding precision medicine in paediatric oncology shows promise to have a positive impact on how children with cancer will be treated in the future. While…”
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Chemoprevention of rat hepatocarcinogenesis with histone deacetylase inhibitors: Efficacy of tributyrin, a butyric acid prodrug by Kuroiwa‐Trzmielina, Joice, de Conti, Aline, Scolastici, Clarissa, Pereira, Douglas, Horst, Maria Aderuza, Purgatto, Eduardo, Ong, Thomas Prates, Moreno, Fernando Salvador

“…Hepatocellular carcinoma (HCC) ranks in prevalence and mortality among top 10 cancers worldwide. Butyric acid (BA), a member of histone deacetylase inhibitors…”
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SNP rs16906252C>T Is an Expression and Methylation Quantitative Trait Locus Associated with an Increased Risk of Developing MGMT-Methylated Colorectal Cancer by Kuroiwa-Trzmielina, Joice, Wang, Fan, Rapkins, Robert W, Ward, Robyn L, Buchanan, Daniel D, Win, Aung Ko, Clendenning, Mark, Rosty, Christophe, Southey, Melissa C, Winship, Ingrid M, Hopper, John L, Jenkins, Mark A, Olivier, Jake, Hawkins, Nicholas J, Hitchins, Megan P

“…Methylation of the MGMT promoter is the major cause of O -methylguanine methyltransferase deficiency in cancer and has been associated with the T variant of…”
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The chemopreventive activity of the butyric acid prodrug tributyrin in experimental rat hepatocarcinogenesis is associated with p53 acetylation and activation of the p53 apoptotic signaling pathway by de Conti, Aline, Tryndyak, Volodymyr, Koturbash, Igor, Heidor, Renato, Kuroiwa-Trzmielina, Joice, Ong, Thomas P, Beland, Frederick A, Moreno, Fernando S, Pogribny, Igor P

“…The reversibility of non-genotoxic phenotypic alterations has been explored in order to develop novel preventive and therapeutic approaches for cancer control…”
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Abstract 60: Constitutional MGMT promoter methylation and allelic expression imbalance are associated with the c.-56C>T (rs16906252) variant by Kuroiwa-Trzmielina, Joice, Hawkins, Nicholas J., Ward, Robyn L., Hitchins, Megan P.

“…Abstract Loss of expression of the DNA repair protein MGMT in cancer is associated with a mutator phenotype and frequently occurs due to promoter methylation…”
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Chemopreventive effects of the dietary histone deacetylase inhibitor tributyrin alone or in combination with vitamin A during the promotion phase of rat hepatocarcinogenesis by de Conti, Aline, Kuroiwa-Trzmielina, Joice, Horst, Maria A, Bassoli, Bruna K, Chagas, Carlos E.A, Purgatto, Eduardo, Cavalher, Felicia P, Camargo, Anamaria A, Jordão, Alceu A. Jr, Vannucchi, Hélio, Scolastici, Clarissa, Ong, Thomas P, Moreno, Fernando S

“…The chemopreventive effects of tributyrin (TB) and vitamin A (VA), alone or in combination, were investigated during the promotion phase of rat…”
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