Clinical study on the effect of chemotherapy in the treatment of pancreatic cancer

The effect of chemotherapy in the treatment of pancreatic cancer was evaluated on the basis of prognosis in 299 patients treated at the Kobe University Hospital and the Interhospital Cooperative Study Group for Multidisciplinary Approaches to Treatment of Pancreatic and Biliary Cancer. One hundred f...

Full description

Saved in:

Bibliographic Details
Published in:	Gan to kagaku ryoho Vol. 15; no. 4 Pt 1; p. 703
Main Authors:	Yamamoto, M, Saitoh, Y, Ohyanagi, H, Ishida, T, Shimada, Y, Tagashira, Y, Fujimoto, T, Kurogoh, F, Okumura, S, Uchida, K
Format:	Journal Article
Language:	Japanese
Published:	Japan 01-04-1988
Subjects:	Antineoplastic Combined Chemotherapy Protocols - therapeutic use Female Fluorouracil - administration & dosage Humans Lymphatic Metastasis Male Middle Aged Pancreatic Neoplasms - drug therapy Pancreatic Neoplasms - mortality Pancreatic Neoplasms - pathology Prognosis Tegafur - administration & dosage Uracil - administration & dosage
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The effect of chemotherapy in the treatment of pancreatic cancer was evaluated on the basis of prognosis in 299 patients treated at the Kobe University Hospital and the Interhospital Cooperative Study Group for Multidisciplinary Approaches to Treatment of Pancreatic and Biliary Cancer. One hundred forty-three patients with pancreatic cancer were treated with a number of chemotherapeutic agents, while ninety-eight patients did not receive any chemotherapy. There were no significant differences in clinical characteristics between the two groups. The treated patients had a median survival time of 6 months and a one-year cumulative survival rate of 25.3%. These were significantly different compared with figures of 3 months and 9.5% for non-treated control patients. A chemotherapy regimen consisting of fluoropyrimidines was also confirmed to be effective. These results suggest that the chemotherapeutic approach appears quite promising and is effective for the treatment of pancreatic cancer.
ISSN:	0385-0684