Search Results - "Kuroda, Masataka"
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Development of an In Silico Prediction Model for P‑glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration
Published in Journal of medicinal chemistry (11-03-2021)“…Developing in silico models to predict the brain penetration of drugs remains a challenge owing to the intricate involvement of multiple transport systems in…”
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2
Idiopathic pulmonary fibrosis-specific Bayesian network integrating extracellular vesicle proteome and clinical information
Published in Scientific reports (15-01-2024)“…Idiopathic pulmonary fibrosis (IPF) is a progressive disease characterized by severe lung fibrosis and a poor prognosis. Although the biomolecules related to…”
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3
Latent inter-organ mechanism of idiopathic pulmonary fibrosis unveiled by a generative computational approach
Published in Scientific reports (11-12-2023)“…Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive disease characterized by complex lung pathogenesis affecting approximately three million…”
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4
Two- and Three-Dimensional Transesophageal Echocardiography for Two Separate Primary Cardiac Lymphomas in the Right Heart
Published in Anesthesia and analgesia (01-07-2017)Get full text
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5
The Usefulness of Three-Dimensional Transesophageal Echocardiography for a Primum Atrial Septal Defect
Published in Anesthesia and analgesia (01-11-2015)Get full text
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6
Discovery of evocalcet, a next-generation calcium-sensing receptor agonist for the treatment of hyperparathyroidism
Published in Bioorganic & medicinal chemistry letters (15-06-2018)“…[Display omitted] •Optimization from cinacalcet resulted in the discovery of evocalcet.•CYP2D6 inhibition observed in cinacalcet is completely solved in…”
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Association of Preoperative Right and Left Ventricular Diastolic Dysfunction with Postoperative Atrial Fibrillation in Patients Undergoing Lung Surgery: A Prospective Observational Study
Published in Journal of cardiothoracic and vascular anesthesia (01-04-2017)“…Objectives To clarify the relationship between right and left ventricular (RV and LV) diastolic function and postoperative atrial fibrillation (POAF), and the…”
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A novel descriptor based on atom-pair properties
Published in Journal of cheminformatics (05-01-2017)Get full text
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9
Role of Cys residues of C-terminal SH2 domain of phosphoinositide 3-kinase in its conformational stability and CD28-binding ability
Published in Chemical thermodynamics and thermal analysis (01-12-2022)“…Proteins fold into their most stable yet dynamic structures that enable their functions and exist in a balance between stability and instability. Protein…”
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Effect of lateral body position on transesophageal echocardiography images and the association with patient characteristics: A prospective observational study
Published in Annals of cardiac anaesthesia (01-07-2015)“…Changes in heart position are occasionally observed on the transesophageal echocardiography (TEE) image screen after changing the body position from supine to…”
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11
Structures of TMC-95A−D: Novel Proteasome Inhibitors from Apiospora montagnei Sacc. TC 1093
Published in Journal of organic chemistry (25-02-2000)“…Four novel proteasome inhibitors, TMC-95A-D (1-4) have been isolated from the fermentation broth of Apiospora montagnei Sacc. TC 1093, isolated from a soil…”
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Phosphoenolpyruvic Acid, an Intermediary Metabolite of Glycolysis, as a Potential Cytoprotectant and Anti-oxidant in HeLa Cells
Published in Biological & pharmaceutical bulletin (2012)“…This study examined the cytoprotective and anti-oxidative properties of phosphoenolpyruvic acid (PEP), a glycolysis metabolite with a high-energy phosphate…”
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13
An Ultrasonic Motor for Use at Ultralow Temperature Using Lead Magnesium Niobate--Lead Titanate Single Crystal
Published in Japanese Journal of Applied Physics (01-07-2012)“…In this study, an ultrasonic motor for use at ultralow temperatures has been fabricated and evaluated. The motor has a bolt-clamped Langevin-type transducer…”
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14
Preoperative depression is a risk factor for postoperative short-term and long-term cognitive dysfunction in patients with diabetes mellitus
Published in Journal of anesthesia (01-02-2011)“…Purpose To identify whether the presence of preoperative depression in patients with diabetes mellitus is a risk factor for postoperative cognitive dysfunction…”
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15
An Ultrasonic Motor for Use at Ultralow Temperature Using Lead Magnesium Niobate–Lead Titanate Single Crystal
Published in Japanese Journal of Applied Physics (01-07-2012)Get full text
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Association between cerebrovascular carbon dioxide reactivity and postoperative short-term and long-term cognitive dysfunction in patients with diabetes mellitus
Published in Journal of anesthesia (01-10-2011)“…Purpose Our intent was to identify whether cerebrovascular CO 2 reactivity in diabetic patients is a risk factor for postoperative cognitive dysfunction after…”
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Differential effects of hyperventilation on cerebral blood flow velocity after tourniquet deflation during sevoflurane, isoflurane, or propofol anesthesia
Published in Journal of anesthesia (01-08-2010)“…The purpose of this study was to compare the degree of increase in middle cerebral artery (MCA) blood flow velocity after tourniquet deflation when modulating…”
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18
Regurgitant leak from the area between the stent post and the sewing ring of a stented bovine pericardial valve implanted in the aortic valve position
Published in Cardiovascular ultrasound (28-11-2010)“…Biologic valves can sometimes have a small closure or leakage backflow jet originating from the central coaptation point. This is physiologic regurgitation…”
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A novel descriptor based on atom-pair properties
Published in Journal of cheminformatics (2017)“…Background Molecular descriptors have been widely used to predict biological activities and physicochemical properties or to analyze chemical libraries on the…”
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20
Coronary artery spasm immediately after insertion of a laryngeal mask airway during induction of general anesthesia
Published in Masui. The Japanese journal of anesthesiology (01-10-2011)“…We describe the case of a 73-year-old woman scheduled for tendon sheath release for carpal tunnel syndrome under general anesthesia. Preoperatively, she had…”
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