Search Results - "Kuroda, Jun‐ichiro"

NC‐6300, an epirubicin‐incorporating micelle, extends the antitumor effect and reduces the cardiotoxicity of epirubicin by Takahashi, Amane, Yamamoto, Yoshiyuki, Yasunaga, Masahiro, Koga, Yoshikatsu, Kuroda, Jun‐ichiro, Takigahira, Misato, Harada, Mitsunori, Saito, Hiroyuki, Hayashi, Tatsuyuki, Kato, Yasuki, Kinoshita, Taira, Ohkohchi, Nobuhiro, Hyodo, Ichinosuke, Matsumura, Yasuhiro

“…Epirubicin is widely used to treat various human tumors. However, it is difficult to achieve a sufficient antitumor effect because of dosage limitation to…”
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Melanotic pilocytic astrocytoma by Yamada, Rin, Inoue, Hirotaka, Kuroda, Jun‐ichiro, Furuta, Takuya, Moritsubo, Mayuko, Shinojima, Naoki, Mukasa, Akitake, Mikami, Yoshiki

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An initial experience of machine learning based on multi-sequence texture parameters in magnetic resonance imaging to differentiate glioblastoma from brain metastases by Tateishi, Machiko, Nakaura, Takeshi, Kitajima, Mika, Uetani, Hiroyuki, Nakagawa, Masataka, Inoue, Taihei, Kuroda, Jun-ichiro, Mukasa, Akitake, Yamashita, Yasuyuki

“…To evaluate the performance of a machine learning method based on texture parameters in conventional magnetic resonance imaging (MRI) in differentiating…”
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Differentiating Between Primary Central Nervous System Lymphomas and Glioblastomas: Combined Use of Perfusion-Weighted and Diffusion-Weighted Magnetic Resonance Imaging by Makino, Keishi, Hirai, Toshinori, Nakamura, Hideo, Kuroda, Jun-ichiro, Shinojima, Naoki, Uetani, Hiroyuki, Kitajima, Mika, Yano, Shigetoshi

“…The purpose of this study was to determine whether combined diffusion-weighted imaging and dynamic susceptibility contrast-enhanced perfusion-weighted imaging…”
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Potent antitumor effect of SN‐38‐incorporating polymeric micelle, NK012, against malignant glioma by Kuroda, Jun‐ichiro, Kuratsu, Jun‐ichi, Yasunaga, Masahiro, Koga, Yoshikatsu, Saito, Yohei, Matsumura, Yasuhiro

“…Recent published reports on clinical trials of CPT‐11 indicate the effectiveness of this compound, a prodrug of SN‐38, against malignant glioma in combination…”
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Molecular imaging using an anti-human tissue factor monoclonal antibody in an orthotopic glioma xenograft model by Takashima, Hiroki, Tsuji, Atsushi B., Saga, Tsuneo, Yasunaga, Masahiro, Koga, Yoshikatsu, Kuroda, Jun-ichiro, Yano, Shigetoshi, Kuratsu, Jun-ichi, Matsumura, Yasuhiro

“…Nuclear medicine examinations for imaging gliomas have been introduced into clinical practice to evaluate the grade of malignancy and determine sampling…”
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Antitumor effect of fibrin glue containing temozolomide against malignant glioma by Anai, Shigeo, Hide, Takuichiro, Takezaki, Tatsuya, Kuroda, Jun‐ichiro, Shinojima, Naoki, Makino, Keishi, Nakamura, Hideo, Yano, Shigetoshi, Kuratsu, Jun‐ichi

“…Temozolomide (TMZ), used to treat glioblastoma and malignant glioma, induces autophagy, apoptosis and senescence in cancer cells. We investigated fibrin glue…”
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Diffusely infiltrating glioma with CREBBP–BCORL1 fusion showing overexpression of not only BCORL1 but BCOR: A case report by Yamazaki, Ayako, Arai, Yasuhito, Fukuoka, Kohei, Nakano, Yoshiko, Hama, Natsuko, Nakata, Satoshi, Makino, Keishi, Kuroda, Jun-Ichiro, Shinojima, Naoki, Mukasa, Akitake, Mikami, Yoshiki, Ichimura, Koichi, Shibata, Tatsuhiro, Yokoo, Hideaki, Nobusawa, Sumihito

“…BCORL1 encodes a transcriptional corepressor homolog to BCOR. BCORL1 rearrangements have been previously described as rare events, and among them,…”
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A case of an epithelioid glioblastoma with the BRAF V600E mutation colocalized with BRAF intact low‐grade diffuse astrocytoma by Kuroda, Jun‐Ichiro, Nobusawa, Sumihito, Nakamura, Hideo, Yokoo, Hideaki, Ueda, Ryuta, Makino, Keishi, Yano, Shigetoshi, Kuratsu, Jun‐ichi

“…Epithelioid glioblastomas are one of the rarest histological variants of glioblastomas, which are not formally recognized by the World Health Organization…”
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2-Methylthio Conversion of N6-Isopentenyladenosine in Mitochondrial tRNAs by CDK5RAP1 Promotes the Maintenance of Glioma-Initiating Cells by Yamamoto, Takahiro, Fujimura, Atsushi, Wei, Fan-Yan, Shinojima, Naoki, Kuroda, Jun-ichiro, Mukasa, Akitake, Tomizawa, Kazuhito

“…2-Methylthio-N6-isopentenyl modification of adenosine (ms2i6A) is an evolutionally conserved modification found in mitochondrial (mt)-tRNAs. Cdk5 regulatory…”
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Discovery of an uncovered region in fibrin clots and its clinical significance by Hisada, Yohei, Yasunaga, Masahiro, Hanaoka, Shingo, Saijou, Shinji, Sugino, Takashi, Tsuji, Atsushi, Saga, Tsuneo, Tsumoto, Kouhei, Manabe, Shino, Kuroda, Jun-ichiro, Kuratsu, Jun-ichi, Matsumura, Yasuhiro

“…Despite the pathological importance of fibrin clot formation, little is known about the structure of these clots because X-ray and nuclear magnetic resonance…”
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The antitumor activity of NK012, an SN‐38–incorporating micelle, in combination with bevacizumab against lung cancer xenografts by Kenmotsu, Hirotsugu, Yasunaga, Masahiro, Goto, Koichi, Nagano, Tatsuya, Kuroda, Jun‐ichiro, Koga, Yoshikatsu, Takahashi, Amane, Nishiwaki, Yutaka, Matsumura, Yasuhiro

“…BACKGROUND: It has been demonstrated that NK012, a novel 7‐ethyl‐10‐hydroxycamptothecin (SN‐38)‐incorporating polymeric micelle, exerts significantly more…”
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Synergistic antitumor activity of the SN‐38‐incorporating polymeric micelles NK012 with S‐1 in a mouse model of non‐small cell lung cancer by Nagano, Tatsuya, Yasunaga, Masahiro, Goto, Koichi, Kenmotsu, Hirotsugu, Koga, Yoshikatsu, Kuroda, Jun‐ichiro, Nishimura, Yoshihiro, Sugino, Takashi, Nishiwaki, Yutaka, Matsumura, Yasuhiro

“…The combination therapy of CPT‐11, a prodrug of SN‐38, with S‐1, a dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine, shows a high clinical response…”
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Prognostic impact of completion of initial high-dose methotrexate therapy on primary central nervous system lymphoma: a single institution experience by Makino, Keishi, Nakamura, Hideo, Hide, Taku-ichiro, Kuroda, Jun-ichiro, Yano, Shigetoshi, Kuratsu, Jun-ichi

“…Background This retrospective single-center study assessed the feasibility, outcomes, and side-effects of high-dose methotrexate (HD-MTX) plus procarbazine in…”
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Antitumor Effect of NK012, a 7-Ethyl-10-Hydroxycamptothecin–Incorporating Polymeric Micelle, on U87MG Orthotopic Glioblastoma in Mice Compared with Irinotecan Hydrochloride in Combination with Bevacizumab by Kuroda, Jun-ichiro, Kuratsu, Jun-ichi, Yasunaga, Masahiro, Koga, Yoshikatsu, Kenmotsu, Hirotsugu, Sugino, Takashi, Matsumura, Yasuhiro

“…Purpose: To clarify the effect of bevacizumab on NK012 therapy in mice bearing U87MG glioblastoma orthotopic xenografts in comparison with the combination…”
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Skull Metastasis From Intrahepatic Cholangiocarcinoma: Report of 3 Cases and Review of the Literature by FUJIMOTO, Kenji, KURODA, Jun-ichiro, MAKINO, Keishi, HASEGAWA, Yu, KURATSU, Jun-ichi

“…Skull metastases occur in patients with various malignancies; however, those resulting from intrahepatic cholangiocarcinoma (ICC) have been rarely reported. In…”
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Detailed Distribution of NK012, an SN-38-Incorporating Micelle, in the Liver and Its Potent Antitumor Effects in Mice Bearing Liver Metastases by TAKAHASHI, Amane, OHKOHCHI, Nobuhiro, YASUNAGA, Masahiro, KURODA, Jun-Ichiro, KOGA, Yoshikatsu, KENMOTSU, Hirotsugu, KINOSHITA, Taira, MATSUMURA, Yasuhiro

“…To clarify and compare the antitumor effects and specific biodistribution of NK012, an SN-38-incorporating polymeric micelle, in mice bearing multiple liver…”
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Antitumor Activity of NK012 Combined with Cisplatin against Small Cell Lung Cancer and Intestinal Mucosal Changes in Tumor-Bearing Mouse after Treatment by Nagano, Tatsuya, Yasunaga, Masahiro, Goto, Koichi, Kenmotsu, Hirotsugu, Koga, Yoshikatsu, Kuroda, Jun-Ichiro, Nishimura, Yoshihiro, Sugino, Takashi, Nishiwaki, Yutaka, Matsumura, Yasuhiro

“…Purpose: To investigate the advantages of treatment with the SN-38–incorporating polymeric micelles NK012 over CPT-11 in combination with cisplatin [ cis…”
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Higher incidence of epilepsy in meningiomas located on the premotor cortex: a voxel-wise statistical analysis by Hamasaki, Tadashi, Yamada, Kazumichi, Yano, Shigetoshi, Nakamura, Hideo, Makino, Keishi, Hide, Taku-ichiro, Hasegawa, Yu, Kuroda, Jun-ichiro, Hirai, Toshinori, Kuratsu, Jun-ichi

“…Background A substantial number of patients with brain tumors develop recurrent seizures, known as tumor-associated epilepsy. It is important to identify…”
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Postoperative disappearance of leptomeningeal enhancement around the brainstem in glioblastoma by Inoue, Hirotaka, Kuroda, Jun-ichiro, Uetani, Hiroyuki, Matsuyama, Tomohiko, Kaku, Yasuyuki, Shinojima, Naoki, Hirai, Toshinori, Mukasa, Akitake

“…Purpose Leptomeningeal enhancement (LME) suggests leptomeningeal dissemination (LMD) of tumor cells, which is a complication of end-stage glioblastoma, and is…”
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