Search Results - "Kurman, CC"

Studies of the expression of the Wiskott-Aldrich syndrome protein by Stewart, D M, Treiber-Held, S, Kurman, C C, Facchetti, F, Notarangelo, L D, Nelson, D L

“…The Wiskott-Aldrich syndrome (WAS) is an X-linked disorder characterized by thrombocytopenia, eczema, disorders in cell-mediated and humoral immunity, and a…”
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Soluble interleukin 2 receptors are released from activated human lymphoid cells in vitro by Rubin, LA, Kurman, CC, Fritz, ME, Biddison, WE, Boutin, B, Yarchoan, R, Nelson, DL

“…With the use of an enzyme-linked immunoabsorbent assay to measure soluble human interleukin 2 receptors (IL 2R), certain human T cell leukemia virus I (HTLV…”
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Molecular genetic analysis of X-linked hypogammaglobulinemia and isolated growth hormone deficiency by Stewart, DM, Notarangelo, LD, Kurman, CC, Staudt, LM, Nelson, DL

“…In 1980 the clinical syndrome of X-linked hypogammaglobulinemia and isolated growth hormone deficiency (XLA/GHD) was described. XLA/GHD patients have reduced…”
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Serial levels of soluble interleukin 2 receptor in the peripheral blood of patients with rheumatoid arthritis: correlations with disease activity by Rubin, L A, Snow, K M, Kurman, C C, Nelson, D L, Keystone, E C

“…We serially assayed soluble interleukin 2 receptor (sIL-2R) levels in the peripheral blood (PB) of 22 patients with rheumatoid arthritis (RA) followed for a…”
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Soluble interleukin-2 receptor alpha is elevated in sera of patients with benign ovarian neoplasms and epithelial ovarian cancer by Hurteau, J A, Woolas, R P, Jacobs, I J, Oram, D C, Kurman, C C, Rubin, L A, Nelson, D L, Berchuck, A, Bast, Jr, R C, Mills, G B

“…Previous studies have established that soluble interleukin-2 receptor alpha (sIL-2R alpha) levels are elevated in ascites and sera from individuals with…”
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Targeting human IL-2 receptors for diagnosis and therapy by Nelson, D L, Kurman, C C

“…The high-affinity interleukin-2 receptor (IL-2R) is a multichain receptor with at least three IL-2 binding chains: IL-2R alpha (55 kDa) bound by the monoclonal…”
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Molecular genetic analysis of the primary immunodeficiency disorders by Nelson, D L, Kurman, C C

“…Exciting progress in the search for the genetic basis of the primary immune deficiency disorders continues to shed insight into functioning of the immune…”
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Elevated serum levels of soluble Tac peptide in adult T-cell leukemia: correlation with clinical status during chemotherapy by Marcon, L, Rubin, L A, Kurman, C C, Fritz, M E, Longo, D L, Uchiyama, T, Edwards, B K, Nelson, D L

“…Adult T-cell leukemia associated with human T-cell leukemia virus type I (HTLV-I) is characterized by a clonal expansion of a CD4-positive subset of T…”
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Soluble Tac peptide is present in the urine of normal individuals and at elevated levels in patients with adult T cell leukaemia (ATL) by MARCON, L, FRITZ, M. E, KURMAN, C. C, JENSEN, J. C, NELSON, D. L

“…The T lymphocyte-derived lymphokine interleukin 2 and the cell-associated receptor for this molecule play major roles in the activation and regulation of the…”
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Racial differences in serum immunoglobulin levels: relationship to cigarette smoking, T-cell subsets, and soluble interleukin-2 receptors by Tollerud, D J, Brown, L M, Blattner, W A, Weiss, S T, Maloney, E M, Kurman, C C, Nelson, D L, Hoover, R N

“…To investigate the influence of race, cigarette smoking, and immunologic parameters on serum immunoglobulins, we analyzed serum IgG, IgA, and IgM levels in 455…”
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A monoclonal antibody 7G7/B6, binds to an epitope on the human interleukin-2 (IL-2) receptor that is distinct from that recognized by IL-2 or anti-Tac by Rubin, L A, Kurman, C C, Biddison, W E, Goldman, N D, Nelson, D L

“…Murine splenocytes immune to influenza virus-activated human T-cells were fused with SP2/0 cells, selected in chemically defined HAT media, and subcloned to…”
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Characterization of a new IL-6-dependent human B-lymphoma cell line in long term culture by Bock, G H, Long, C A, Riley, M L, White, J D, Kurman, C C, Fleisher, T A, Tsokos, M, Brown, M, Serbousek, D, Schwietermann, W D

“…We have established a cell line (DS-1) of B-cell lineage in long-term culture. It was derived from an immunodeficient patient with intestinal lymphangiectasia…”
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Temporal variability in immunological parameters: Peripheral blood mononuclear cell subsets, serum immunoglobulins, and soluble markers of immune system activation by Maloney, Elizabeth M., Brown, Linda Morris, Kurman, Carole C., Fuchs, Dietmar, Nelson, David L., Wachter, Helmut, Blattner, William A., Tollerud, David J.

“…T‐cell subsets and soluble factors of immune system activation are increasingly used as biologic markers of disease and predictors of disease progression. For…”
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Nitrosamine-induced transplantable pancreatic ductal adenocarcinoma in inbred Syrian hamsters by Sindelar, W F, Kurman, C C

“…A pancreatic ductal carcinoma, designated CBP, was established as a transplantable tumor line in the CB/SsLak inbred strain of Syrian golden hamsters. The…”
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Active immunization of hamsters against pancreatic carcinoma with lipid-treated cells or their shed antigens by SKORNICK, Y, KURMAN, C. C, SINDELAR, W. F

“…Increasing membrane lipid microviscosity of cells by treatment with cholesterol esters such as cholesterol hemisuccinate (CHS) enhances immunogenicity,…”
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Nitrosamine-induced pancreatic carcinogenesis in outbred and inbred Syrian hamsters by Sindelar, W F, Kurman, C C

“…Pancreatic carcinogenesis was investigated in outbred and in five strains of inbred Syrian golden hamsters utilizing the nitrosamines…”
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Genes and molecules involved in T-cell differentiation by Nelson, D L, Serbousek, D E, Kurman, C C

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Antigen-stimulated human B cell clones are committed to the production of a single class of antibody in vitro by Yarchoan, R, Engler, RJ, Barrow, LA, Kurman, CC, Nelson, DL

“…We have investigated the isotype(s) of antibody produced in vitro by antigen-stimulated human B cell clones. An analysis of the class(es) of antibody produced…”
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Demonstration of type-R and type-C virus particles in hamster pancreatic adenocarcinomas by Sindelar, W F, Tralka, T S, Kurman, C C, Hyatt, C L, Henson, E R

“…Two transplantable solid tumors (CBP and PDP) and two continuous cultured cell lines (CBP-TC and PDP-TC) were established from nitrosamine-induced pancreatic…”
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Release of sIL-2Rα from and Activation of Native Human Peripheral Blood Mononuclear Cells by Recombinant IL-15 by Treiber-Held, Stephanie, Stewart, Donn M., Barraclough, Holly A., Kurman, Carole C., Nelson, David L.

“…The cytokine interleukin (IL)-15 shares several activities with IL-2. Both cytokines induced expression of cell-surface IL-2Rα (CD25) on freshly isolated human…”
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