Search Results - "Kurland, Brenda"
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Whole‐Body Characterization of Estrogen Receptor Status in Metastatic Breast Cancer with 16α‐18F‐Fluoro‐17β‐Estradiol Positron Emission Tomography: Meta‐Analysis and Recommendations for Integration into Clinical Applications
Published in The oncologist (Dayton, Ohio) (01-10-2020)“…Estrogen receptor (ER) status by immunohistochemistry (IHC) of cancer tissue is currently used to direct endocrine therapy in breast cancer. Positron emission…”
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Radiomic Analysis: Study Design, Statistical Analysis, and Other Bias Mitigation Strategies
Published in Radiology (01-08-2022)“…Rapid advances in automated methods for extracting large numbers of quantitative features from medical images have led to tremendous growth of publications…”
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Quantitative imaging biomarkers: A review of statistical methods for technical performance assessment
Published in Statistical methods in medical research (01-02-2015)“…Technological developments and greater rigor in the quantitative measurement of biological features in medical images have given rise to an increased interest…”
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Sensitive Detection of Mono- and Polyclonal ESR1 Mutations in Primary Tumors, Metastatic Lesions, and Cell-Free DNA of Breast Cancer Patients
Published in Clinical cancer research (01-03-2016)“…Given the clinical relevance of ESR1 mutations as potential drivers of resistance to endocrine therapy, this study used sensitive detection methods to…”
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Heterogeneity in Metastatic Breast Cancer 18F-Fluoroestradiol Uptake: Clinically Actionable, Biologically Illuminating?
Published in The Journal of nuclear medicine (1978) (01-08-2018)Get full text
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Heterogeneity in Metastatic Breast Cancer 18 F-Fluoroestradiol Uptake: Clinically Actionable, Biologically Illuminating?
Published in Journal of Nuclear Medicine (01-08-2018)Get full text
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Estrogen Receptor Binding (18F-FES PET) and Glycolytic Activity (18F-FDG PET) Predict Progression-Free Survival on Endocrine Therapy in Patients with ER+ Breast Cancer
Published in Clinical cancer research (15-01-2017)“…F-fluoroestradiol (FES) PET scans measure regional estrogen binding, and F-fluorodeoxyglucose (FDG) PET measures tumor glycolytic activity. We examined…”
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Quantitative Diffusion-Weighted Imaging as an Adjunct to Conventional Breast MRI for Improved Positive Predictive Value
Published in American journal of roentgenology (1976) (01-12-2009)“…The purpose of our study was to investigate whether adding diffusion-weighted imaging (DWI) to dynamic contrast-enhanced MRI (DCE-MRI) could improve the…”
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Cisplatin and Radiotherapy With or Without Erlotinib in Locally Advanced Squamous Cell Carcinoma of the Head and Neck: A Randomized Phase II Trial
Published in Journal of clinical oncology (10-04-2013)“…The combination of cisplatin and radiotherapy is a standard treatment for patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN)…”
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Combined VLA-4-Targeted Radionuclide Therapy and Immunotherapy in a Mouse Model of Melanoma
Published in Journal of Nuclear Medicine (01-12-2018)“…Very late antigen-4 (VLA-4; also known as integrin α β ) is expressed at high levels in aggressive and metastatic melanoma tumors and may provide an ideal…”
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Caveolin-1 promotes the tumor suppressor properties of oncogene-induced cellular senescence
Published in The Journal of biological chemistry (02-02-2018)“…Oncogene-induced senescence (OIS) is considered a powerful tumor suppressor mechanism. Caveolin-1 acts as a scaffolding protein to functionally regulate…”
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Phase II Study of Systemic High-dose Methotrexate and Intrathecal Liposomal Cytarabine for Treatment of Leptomeningeal Carcinomatosis From Breast Cancer
Published in Clinical breast cancer (01-10-2019)“…Metastatic breast cancer frequently leads to brain metastases and, less commonly, leptomeningeal carcinomatosis (LC). Once cerebrospinal fluid involvement…”
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Prospective Neurocognitive Function Over 5 Years After Allogeneic Hematopoietic Cell Transplantation for Cancer Survivors Compared With Matched Controls at 5 Years
Published in Journal of clinical oncology (10-06-2011)“…Research has documented cognitive deficits both before and after high-dose treatment followed by allogeneic hematopoietic cell transplantation (HCT), with…”
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Use of Response Permutation to Measure an Imaging Dataset’s Susceptibility to Overfitting by Selected Standard Analysis Pipelines
Published in Academic radiology (01-09-2024)“…This study demonstrates a method for quantifying the impact of overfitting on the receiving operator characteristic curve (AUC) when using standard analysis…”
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Acquired Resistance to the Hsp90 Inhibitor, Ganetespib, in KRAS- Mutant NSCLC Is Mediated via Reactivation of the ERK-p90RSK-mTOR Signaling Network
Published in Molecular cancer therapeutics (01-05-2017)“…Approximately 25% of non-small cell lung cancer (NSCLC) patients have mutations, and no effective therapeutic strategy exists for these patients. The use of…”
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Do non-daily smokers compensate for reduced cigarette consumption when smoking very-low-nicotine-content cigarettes?
Published in Psychopharmacology (01-12-2018)“…Rationale The Food and Drug Administration is considering severely restricting the nicotine in cigarettes, to reduce smoking. A study showed that non-daily,…”
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Comparison of PD‐L1 immunohistochemistry assays and response to PD‐1/L1 inhibitors in advanced non‐small‐cell lung cancer in clinical practice
Published in Histopathology (01-01-2019)“…Aims Several studies have demonstrated analytical comparability between different PD‐L1 assays, but their clinical validity in non‐small‐cell lung cancer in…”
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Preclinical Evidence for Combined Use of Aromatase Inhibitors and NSAIDs as Preventive Agents of Tobacco-Induced Lung Cancer
Published in Journal of thoracic oncology (01-03-2018)“…A hormonal role in NSCLC development is well documented. We previously showed that the aromatase inhibitor (AI) anastrozole decreased development of tobacco…”
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Neuropathology of nondemented aging: Presumptive evidence for preclinical Alzheimer disease
Published in Neurobiology of aging (01-07-2009)“…Abstract Objective To determine the frequency and possible cognitive effect of histological Alzheimer's disease (AD) in autopsied older nondemented…”
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