Search Results - "Kurk, Sophie"
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Association between body composition, survival, and toxicity in advanced esophagogastric cancer patients receiving palliative chemotherapy
Published in Journal of cachexia, sarcopenia and muscle (01-02-2019)“…Background Palliative systemic treatment in patients with advanced or metastatic esophagogastric cancer may result in improved overall survival and quality of…”
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Impact of different palliative systemic treatments on skeletal muscle mass in metastatic colorectal cancer patients
Published in Journal of cachexia, sarcopenia and muscle (01-10-2018)“…Background Observational studies suggest that loss of skeletal muscle mass (SMM) is associated with chemotherapy‐related toxicity, poor quality of life, and…”
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Trajectory of body mass and skeletal muscle indices and disease progression in metastatic colorectal cancer patients
Published in The American journal of clinical nutrition (01-12-2019)“…Knowledge of the evolution of BMI and skeletal muscle index (SMI) measurements during advanced cancer and their relationships with disease progression (PD) is…”
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Skeletal muscle mass loss and dose‐limiting toxicities in metastatic colorectal cancer patients
Published in Journal of cachexia, sarcopenia and muscle (01-08-2019)“…Background Increasing evidence suggests that severe skeletal muscle index (SMI) loss (sarcopenia) is associated with poor overall survival in metastatic…”
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The association between changes in muscle mass and quality of life in patients with metastatic colorectal cancer
Published in Journal of cachexia, sarcopenia and muscle (01-08-2020)“…Background Skeletal muscle mass (SMM) loss is common in metastatic colorectal cancer (mCRC) patients and associated with poor clinical outcomes, including…”
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Use of automated assessment for determining associations of low muscle mass and muscle loss with overall survival in patients with colorectal cancer – A validation study
Published in Clinical nutrition ESPEN (01-10-2024)“…Low muscle mass and skeletal muscle mass (SMM) loss are associated with adverse patient outcomes, but the time-consuming nature of manual SMM quantification…”
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Role of Up-Front Primary Tumor Resection and Tumor Sidedness in the Survival of Synchronous Metastatic Colon Cancer Patients
Published in Digestive surgery (01-09-2021)“…Uncertainty exists about a possible survival benefit of primary tumor resection (PTR) in synchronous metastatic colon cancer (mCC). Since sidedness of the…”
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8
A Systematic Review of the Diagnostic Value of CT Imaging in Diagnosing Otosclerosis
Published in Otology & neurotology (01-01-2016)“…OBJECTIVE:To evaluate the diagnostic value of computed tomography (CT) in detecting otosclerosis in patients with conductive hearing loss and a clinical…”
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Loss of skeletal muscle index and survival in patients with metastatic colorectal cancer: Secondary analysis of the phase 3 CAIRO3 trial
Published in Cancer medicine (Malden, MA) (01-02-2020)“…Background Low skeletal muscle index (SMI) in metastatic colorectal cancer (mCRC) patients is associated with poor outcomes. The prognostic impact of SMI…”
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Factors Contributing to Cancer-Related Muscle Wasting During First-Line Systemic Treatment for Metastatic Colorectal Cancer
Published in JNCI cancer spectrum (01-06-2019)“…Increasing evidence indicates that loss of muscle mass is associated with adverse outcomes in metastatic colorectal cancer. Here, we investigate which…”
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Worse capecitabine treatment outcome in patients with a low skeletal muscle mass is not explained by altered pharmacokinetics
Published in Cancer medicine (Malden, MA) (01-07-2021)“…Background A low skeletal muscle mass (SMM) has been associated with increased toxicity and shorter survival in cancer patients treated with capecitabine, an…”
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Feasibility of 7-T fluorine magnetic resonance spectroscopic imaging (19F MRSI) for TAS-102 metabolite detection in the liver of patients with metastatic colorectal cancer
Published in European radiology experimental (11-07-2018)“…Trifluridine/tipiracil (TAS-102) has shown a significant overall survival benefit in patients with heavily pre-treated metastatic colorectal cancer. However,…”
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Subgroup analyses of the phase 3 CAIRO3 trial: Association of number and total volume of metastases on survival in patients with metastatic colorectal cancer based on a deep-learning automatic segmentation model
Published in Journal of clinical oncology (20-01-2024)“…130 Background: Maintenance treatment with capecitabine and bevacizumab after capecitabine, oxaliplatin, and bevacizumab therapy in metastatic colorectal…”
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14
Sixty-Day Mortality of Patients With Metastatic Colorectal Cancer Randomized to Systemic Treatment vs Primary Tumor Resection Followed by Systemic Treatment: The CAIRO4 Phase 3 Randomized Clinical Trial
Published in JAMA surgery (01-12-2021)“…The role of primary tumor resection (PTR) in synchronous patients with metastatic colorectal cancer (mCRC) who had unresectable metastases and few or absent…”
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Abstract 1827: The prospective Dutch colorectal cancer cohort: A prospective nation-wide observational cohort study
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Abstract The increasingly complex subclassification of tumors based on clinical and molecular characteristics, as well as the large sample sizes needed for…”
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Impact of skeletal muscle index (SMI) loss during palliative systemic treatment (Tx) on time to progression and overall survival (OS) in metastatic colorectal cancer (mCRC) patients
Published in Journal of clinical oncology (20-05-2017)“…Abstract only 10087 Background: Evidence for a strong link between skeletal muscle depletion and poor outcomes in mCRC is growing. However, the impact of SMI…”
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