Search Results - "Kurita, Ayumi"

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT by Miyauchi, Yuu, Kurita, Ayumi, Yamashita, Ryohei, Takamatsu, Tomoyuki, Ikushiro, Shin’ichi, Mackenzie, Peter I., Tanaka, Yoshitaka, Ishii, Yuji

“…UDP-Glucuronosyltransferase (UGT, Ugt) is a major drug metabolizing enzyme family involved in the glucuronidation and subsequent elimination of drugs and small…”
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Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation by Kurita, Ayumi, Miyauchi, Yuu, Ikushiro, Shin'ichi, Mackenzie, Peter I, Yamada, Hideyuki, Ishii, Yuji

“…UDP-Glucuronosyltransferases (UGTs) are classified into three subfamilies in mice: Ugt1a, 2b, and 2a. In the subfamily, and appear to correspond to human and…”
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Comprehensive characterization of mouse hepatic UDP‐glucuronosyltransferases: Major participation of Ugt2b1 in bisphenol A glucuronidation by Ishii, Yuji, Yamashita, Ryohei, Kurita, Ayumi, Miyauchi, Yuu, Ikushiro, Shin'ichi, Mackenzie, Peter I, Tanaka, Yoshitaka

“…Purpose Bisphenol A (BPA), which exhibits estrogen‐like properties, is a starting material for the synthesis of plastic especially for polycarbonates. The…”
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