Search Results - "Kurimoto, Ryota"

Post-transcriptional regulation of inflammation by RNA-binding proteins via cis-elements of mRNAs by Uchida, Yutaro, Chiba, Tomoki, Kurimoto, Ryota, Asahara, Hiroshi

“…Abstract In human genome, there are approximately 1,500 RNA-binding proteins (RBPs). They can regulate mRNA stability or translational efficiency via ribosomes…”
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Both microRNA-455-5p and -3p repress hypoxia-inducible factor-2α expression and coordinately regulate cartilage homeostasis by Ito, Yoshiaki, Matsuzaki, Tokio, Ayabe, Fumiaki, Mokuda, Sho, Kurimoto, Ryota, Matsushima, Takahide, Tabata, Yusuke, Inotsume, Maiko, Tsutsumi, Hiroki, Liu, Lin, Shinohara, Masahiro, Tanaka, Yoko, Nakamichi, Ryo, Nishida, Keiichiro, Lotz, Martin K., Asahara, Hiroshi

“…Osteoarthritis (OA), the most common aging-related joint disease, is caused by an imbalance between extracellular matrix synthesis and degradation. Here, we…”
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Transcriptional, epigenetic and microRNA regulation of growth plate by Nakamichi, Ryo, Kurimoto, Ryota, Tabata, Yusuke, Asahara, Hirosi

“…Endochondral ossification is a critical event in bone formation, particularly in long shaft bones. Many cellular differentiation processes work in concert to…”
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The tRNA pseudouridine synthase TruB1 regulates the maturation of let‐7 miRNA by Kurimoto, Ryota, Chiba, Tomoki, Ito, Yoshiaki, Matsushima, Takahide, Yano, Yuki, Miyata, Kohei, Yashiro, Yuka, Suzuki, Tsutomu, Tomita, Kozo, Asahara, Hiroshi

“…Let‐7 is an evolutionary conserved microRNA that mediates post‐transcriptional gene silencing to regulate a wide range of biological processes, including…”
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Identification of chemical compounds regulating PD‐L1 by introducing HiBiT‐tagged cells by Uchida, Yutaro, Matsushima, Takahide, Kurimoto, Ryota, Chiba, Tomoki, Inutani, Yuki, Asahara, Hiroshi

“…Programmed death‐ligand 1 (PD‐L1) is a co‐inhibitory molecule expressed on tumor cells. Immune checkpoint inhibitors focusing on the PD‐L1 mechanism are now…”
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Mkx regulates the orthodontic tooth movement via osteoclast induction by Miyazaki, Takayuki, Kurimoto, Ryota, Chiba, Tomoki, Matsushima, Takahide, Nakamichi, Ryo, Tsutsumi, Hiroki, Takada, Kaho, Yagasaki, Lisa, Kato, Tomomi, Shishido, Kana, Kobayashi, Yukiho, Matsumoto, Tsutomu, Moriyama, Keiji, Asahara, Hiroshi

“…Introduction The periodontal ligament (PDL) plays an important role in orthodontic tooth movement; however, the underlying molecular mechanism remains unclear…”
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MicroRNA Expression Profiling, Target Identification, and Validation in Chondrocytes by Chiba, Tomoki, Kurimoto, Ryota, Matsushima, Takahide, Ito, Yoshiaki, Nakamichi, Ryo, Lotz, Martin, Asahara, Hiroshi

“…MicroRNAs (miRNAs) are a class of noncoding small RNAs, which play a critical role in various biological processes including musculoskeletal formation and…”
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Transcriptome analysis of sevoflurane exposure effects at the different brain regions by Yamamoto, Hiroto, Uchida, Yutaro, Chiba, Tomoki, Kurimoto, Ryota, Matsushima, Takahide, Inotsume, Maiko, Ishikawa, Chihiro, Li, Haiyan, Shiga, Takashi, Muratani, Masafumi, Uchida, Tokujiro, Asahara, Hiroshi

“…Sevoflurane is a most frequently used volatile anesthetics, but its molecular mechanisms of action remain unclear. We hypothesized that specific genes play…”
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Generation of a tendon-like tissue from human iPS cells by Tsutsumi, Hiroki, Kurimoto, Ryota, Nakamichi, Ryo, Chiba, Tomoki, Matsushima, Takahide, Fujii, Yuta, Sanada, Risa, Kato, Tomomi, Shishido, Kana, Sakamaki, Yuriko, Kimura, Tsuyoshi, Kishida, Akio, Asahara, Hiroshi

“…Tendons and ligaments are essential connective tissues that connect the muscle and bone. Their recovery from injuries is known to be poor, highlighting the…”
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Crizotinib-Induced Abnormal Signal Processing in the Retina by Ishii, Toshiyuki, Iwasawa, Shunichiro, Kurimoto, Ryota, Maeda, Akemi, Takiguchi, Yuichi, Kaneda, Makoto

“…Molecular target therapy for cancer is characterized by unique adverse effects that are not usually observed with cytotoxic chemotherapy. For example, the…”
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The essential role of Mkx in periodontal ligament on the metabolism of alveolar bone and cementum by Yagasaki, Lisa, Chiba, Tomoki, Kurimoto, Ryota, Nakajima, Mitsuyo, Iwata, Takanori, Asahara, Hiroshi

“…The periodontium is a connective tissue which consists of periodontal ligament, alveolar bone, cementum and gingiva. Periodontal ligament (PDL) is a…”
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Pirfenidone may revert the epithelial-to-mesenchymal transition in human lung adenocarcinoma by Kurimoto, Ryota, Ebata, Takahiro, Iwasawa, Shunichiro, Ishiwata, Tsukasa, Tada, Yuji, Tatsumi, Koichiro, Takiguchi, Yuichi

“…The epithelial-to-mesenchymal transition (EMT) in cancer is associated with invasion, metastasis and chemoresistance. Recent studies have revealed the…”
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Eosinophilic Fasciitis Illustrated by [18F] FDG-PET/CT by Kurimoto, Ryota, Ikeda, Kei, Nakagomi, Daiki, Nakajima, Hiroshi

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Prophylactic dexamethasone for radiation-induced bone-pain flare by Ishiwata, Tsukasa, Iwasawa, Shunichiro, Kurimoto, Ryota, Ebata, Takahiro, Takiguchi, Yuichi

“…A detailed time-course assessment of these symptoms as clearly shown in figure 2 for pain flare in this Article might answer the question. Because 5 day…”
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A case of COVID‐19 with the atypical CT finding by Kurimoto, Ryota, Sakurai, Kenji, Motoori, Ken, Suda, Akira

“…COVID‐19 usually demonstrates the specific pattern of chest CT findings (GGO, inverted‐halo sign, etc). However, some COVID‐19 cases show atypical CT findings…”
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Current status of medical oncology in Japan--reality gleaned from a questionnaire sent to designated cancer care hospitals by Takiguchi, Yuichi, Sekine, Ikuo, Iwasawa, Shunichiro, Kurimoto, Ryota, Sakaida, Emiko, Tamura, Kenji

“…Medical oncology in Japan has a relatively short history, with specialist certification starting in 2006, resulting in 867 certified medical oncologists as of…”
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Safety of a short hydration method for cisplatin administration in comparison with a conventional method-a retrospective study by Sakaida, Emiko, Iwasawa, Shunichiro, Kurimoto, Ryota, Ebata, Takahiro, Imai, Chiaki, Oku, Tomoko, Sekine, Ikuo, Tada, Yuji, Tatsumi, Koichiro, Takiguchi, Yuichi

“…Cisplatin is administered in combination with massive hydration to avoid renal toxicity, making its administration difficult in an outpatient setting. Although…”
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Potential Activity of Amrubicin as a Salvage Therapy for Merkel Cell Carcinoma by Sakaida, Emiko, Ebata, Takahiro, Iwasawa, Shunichiro, Kurimoto, Ryota, Yonemori, Sachiko, Ota, Satoshi, Nakatani, Yukio, Sekine, Ikuo, Takiguchi, Yuichi

“…Merkel cell carcinoma (MCC) is a rare neuroendocrine carcinoma of the skin with an aggressive clinical course. Although anthracycline- and platinum-based…”
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MYC/BCL2 Double-hit Lymphoma in a Patient with Rheumatoid Arthritis Associated with Methotrexate Treatment by Kurimoto, Ryota, Shono, Katsuhiro, Onoda, Masahiro, Yamamoto, Kyohei, Yokota, Akira

“…Several reports have suggested an increased risk of malignant lymphoma in patients with rheumatoid arthritis treated with methotrexate (MTX). We herein…”
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Monitoring the side effects of cancer chemotherapy by Kurimoto, Ryota, Takiguchi, Yuichi

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