Search Results - "Kurilshikov, A."

Role of gut microbiota in chronic low‐grade inflammation as potential driver for atherosclerotic cardiovascular disease: a systematic review of human studies by Munckhof, I. C. L., Kurilshikov, A., Horst, R., Riksen, N. P., Joosten, L. A. B., Zhernakova, A., Fu, J., Keating, S. T., Netea, M. G., Graaf, J., Rutten, J. H. W.

“…Summary A hallmark of obesity is chronic low‐grade inflammation, which plays a major role in the process of atherosclerotic cardiovascular disease (ACVD). Gut…”
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Environmental factors shaping the gut microbiome in a Dutch population by Gacesa, R., Kurilshikov, A., Vich Vila, A., Sinha, T., Klaassen, M. A. Y., Bolte, L. A., Andreu-Sánchez, S., Chen, L., Collij, V., Hu, S., Dekens, J. A. M., Lenters, V. C., Björk, J. R., Swarte, J. C., Swertz, M. A., Jansen, B. H., Gelderloos-Arends, J., Jankipersadsing, S., Hofker, M., Vermeulen, R. C. H., Sanna, S., Harmsen, H. J. M., Wijmenga, C., Fu, J., Zhernakova, A., Weersma, R. K.

“…The gut microbiome is associated with diverse diseases 1 – 3 , but a universal signature of a healthy or unhealthy microbiome has not been identified, and…”
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Gut feelings: the relations between depression, anxiety, psychotropic drugs and the gut microbiome by Brushett, S., Gacesa, R., Vich Vila, A., Brandao Gois, M.F., Andreu-Sánchez, S., Swarte, J.C., Klaassen, M.A.Y., Collij, V., Sinha, T., Bolte, L.A., Wu, J., Swertz, M., de Kroon, M.L.A., Reijneveld, S.A., Wijmenga, C., Weersma, R.K., Fu, J., van Loo, H.M., Kurilshikov, A., Zhernakova, A.

“…The gut microbiome is involved in the bi-directional relationship of the gut - brain axis. As most studies of this relationship are small and do not account…”
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A combination of fecal calprotectin and human beta-defensin 2 facilitates diagnosis and monitoring of inflammatory bowel disease by Gacesa, R., Vich Vila, A., Collij, V., Mujagic, Z., Kurilshikov, A., Voskuil, M.D., Festen, E.A.M., Wijmenga, C., Jonkers, D.M.A.E., Dijkstra, G., Fu, J., Zhernakova, A., Imhann, F., Weersma, R.K.

“…Inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) show a large overlap in clinical presentation, which presents diagnostic challenges. As a…”
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Isolation and characterization of a group of new Proteus bacteriophages by Morozova, V., Kozlova, Yu, Shedko, E., Babkin, I., Kurilshikov, A., Bokovaya, O., Bardashova, A., Yunusova, A., Tikunov, A., Tupikin, A., Ushakova, T., Ryabchikova, E., Tikunova, N.

“…Four lytic Proteus bacteriophages, PM75, PM85, PM93, and PM116, which are active against multi-drug-resistant strains of P. mirabilis, were isolated from…”
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A novel thermophilic Aeribacillus bacteriophage AP45 isolated from the Valley of Geysers, Kamchatka: genome analysis suggests the existence of a new genus within the Siphoviridae family by Morozova, V., Bokovaya, O., Kozlova, Yu, Kurilshikov, A., Babkin, I., Tupikin, A., Bondar, A., Ryabchikova, E., Brayanskaya, A., Peltek, S., Tikunova, N.

“…A novel thermophilic bacteriophage AP45 and its host strain Aeribacillus sp. CEMTC656 were isolated from the Valley of Geysers, Kamchatka Peninsula, Russia…”
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Polymorphism in genes involved in lipid metabolism in MODY patients by Shakhtshneider, E, Ovsyannikova, A, Kurilshikov, A, Ivanoshchuk, D, Rymar, O, Ragino, Y, Voevoda, M

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Lytic bacteriophage PM16 specific for Proteus mirabilis: a novel member of the genus Phikmvvirus by Morozova, V., Kozlova, Yu, Shedko, E., Kurilshikov, A., Babkin, I., Tupikin, A., Yunusova, A., Chernonosov, A., Baykov, I., Кondratov, I., Kabilov, M., Ryabchikova, E., Vlassov, V., Tikunova, N.

“…Lytic Proteus phage PM16, isolated from human faeces, is a novel virus that is specific for Proteus mirabilis cells. Bacteriophage PM16 is characterized by…”
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430 Epigenetic cell-free DNA biomarkers of prostate cancer: The search by massively parallel sequencing by Bondar, A, Kurilshikov, A, Morozkin, E, Zaripov, M, Kabilov, M, Voytsitskiy, V, Vlassov, V, Laktionov, P

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P124 by Bondar, A, Kurilshikov, A, Morozkin, E, Zaripov, M, Kabilov, M, Voytsitskiy, V, Vlassov, V, Laktionov, P

“…Cancer cells display altered methylation signatures distinguishing them from normal cells. Originating from all tissues and cells of the body cell-free DNA…”
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P124 by Morozkin, E, Rykova, E, Bondar, A, Skvortsova, T, Zaporozhchenko, I, Kurilshikov, A, Anikeeva, O, Krasnova, N, Polovnikov, E, Ponomaryova, A, Laktionov, P

“…Epigenetic biomarkers including aberrantly methylated DNA (amDNA) and non-coding RNA such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) in…”
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Large-scale association analyses identify host factors influencing human gut microbiome composition by Kurilshikov, Alexander, Medina-Gomez, Carolina, Bacigalupe, Rodrigo, Radjabzadeh, Djawad, Wang, Jun, Demirkan, Ayse, Le Roy, Caroline I., Raygoza Garay, Juan Antonio, Finnicum, Casey T., Liu, Xingrong, Zhernakova, Daria V., Bonder, Marc Jan, Hansen, Tue H., Frost, Fabian, Rühlemann, Malte C., Turpin, Williams, Moon, Jee-Young, Kim, Han-Na, Lüll, Kreete, Barkan, Elad, Shah, Shiraz A., Fornage, Myriam, Szopinska-Tokov, Joanna, Wallen, Zachary D., Borisevich, Dmitrii, Agreus, Lars, Andreasson, Anna, Bang, Corinna, Bedrani, Larbi, Bell, Jordana T., Bisgaard, Hans, Boehnke, Michael, Boomsma, Dorret I., Burk, Robert D., Claringbould, Annique, Croitoru, Kenneth, Davies, Gareth E., van Duijn, Cornelia M., Duijts, Liesbeth, Falony, Gwen, Fu, Jingyuan, van der Graaf, Adriaan, Hansen, Torben, Homuth, Georg, Hughes, David A., Ijzerman, Richard G., Jackson, Matthew A., Jaddoe, Vincent W. V., Joossens, Marie, Jørgensen, Torben, Keszthelyi, Daniel, Knight, Rob, Laakso, Markku, Laudes, Matthias, Launer, Lenore J., Lieb, Wolfgang, Lusis, Aldons J., Masclee, Ad A. M., Moll, Henriette A., Mujagic, Zlatan, Qibin, Qi, Rothschild, Daphna, Shin, Hocheol, Sørensen, Søren J., Steves, Claire J., Thorsen, Jonathan, Timpson, Nicholas J., Vieira-Silva, Sara, Völker, Uwe, Völzke, Henry, Võsa, Urmo, Wade, Kaitlin H., Walter, Susanna, Watanabe, Kyoko, Weiss, Stefan, Weiss, Frank U., Weissbrod, Omer, Westra, Harm-Jan, Willemsen, Gonneke, Payami, Haydeh, Jonkers, Daisy M. A. E., Arias Vasquez, Alejandro, de Geus, Eco J. C., Stokholm, Jakob, Segal, Eran, Kim, Hyung-Lae, Kaplan, Robert C., Spector, Tim D., Uitterlinden, Andre G., Rivadeneira, Fernando, Franke, Andre, Lerch, Markus M., Franke, Lude, Sanna, Serena, D’Amato, Mauro, Pedersen, Oluf, Paterson, Andrew D., Kraaij, Robert, Raes, Jeroen, Zhernakova, Alexandra

“…To study the effect of host genetics on gut microbiome composition, the MiBioGen consortium curated and analyzed genome-wide genotypes and 16S fecal microbiome…”
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Population-level analysis of gut microbiome variation by Falony, Gwen, Joossens, Marie, Vieira-Silva, Sara, Wang, Jun, Darzi, Youssef, Faust, Karoline, Kurilshikov, Alexander, Bonder, Marc Jan, Valles-Colomer, Mireia, Vandeputte, Doris, Tito, Raul Y., Chaffron, Samuel, Rymenans, Leen, Verspecht, Chloë, De Sutter, Lise, Lima-Mendez, Gipsi, D'hoe, Kevin, Jonckheere, Karl, Homola, Daniel, Garcia, Roberto, Tigchelaar, Ettje F., Eeckhaudt, Linda, Fu, Jingyuan, Henckaerts, Liesbet, Zhernakova, Alexandra, Wijmenga, Cisca, Raes, Jeroen

“…Fecal microbiome variation in the average, healthy population has remained under-investigated. Here, we analyzed two independent, extensively phenotyped…”
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Gut Microbiota Composition of Biliary Atresia Patients Prior to Kasai Portoenterostomy Associates With Long-Term Outcome by van Wessel, Daan B.E., Nomden, M., Bruggink, J.L.M., de Kleine, R.H.J., Kurilshikov, A., Verkade, H.J., Harmsen, H.J.M., Hulscher, Jan B.F.

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Analysis of 1135 gut metagenomes identifies sex-specific resistome profiles by Sinha, Trishla, Vich Vila, Arnau, Garmaeva, Sanzhima, Jankipersadsing, Soesma A., Imhann, Floris, Collij, Valerie, Bonder, Marc Jan, Jiang, Xiaofang, Gurry, Thomas, Alm, Eric J., D'Amato, Mauro, Weersma, Rinse K., Scherjon, Sicco, Wijmenga, Cisca, Fu, Jingyuan, Kurilshikov, Alexander, Zhernakova, Alexandra

“…Several gastrointestinal diseases show a sex imbalance, although the underlying (patho)physiological mechanisms behind this are not well understood. The gut…”
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OP29 Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiome by Bolte, L, Vich Vila, A, Imhann, F, Collij, V, Peters, V, Fu, J, Kurilshikov, A, Campmans-Kuijpers, M, Dijkstra, G, Wijmenga, C, Zhernakova, A, Weersma, R

“…Abstract Background The gut microbiome directly affects the balance of pro-inflammatory and anti-inflammatory responses in the gut. As microbes thrive on…”
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Gut microbiome composition and its relation to joint pain and inflammation by Boer, C.G., Radjabzadeh, D., Medina-Gomez, C., Garmaeva, S., Schiphof, D., Arp, P., Koet, T., Kurilshikov, A., Fu, J., Ikram, A.M., Bierma-Zeinstra, S., Uitterlinden, A.G., Kraaij, R., Zhernakova, A., van Meurs, J.B.

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P006 Host-genetics, dysbiosis, and clinical history explains fecal metabolic alterations in patients with Inflammatory Bowel Disease by Vich Vila, A, Hu, S, Andreu-Sánchez, S, Collij, V, Jansen, D, Ruigrok, R, Abu-Ali, G, Parkinson, J, Al Garawi, A, Schneider, J, Kurilshikov, A, Björk, J, Gacesa, R, Fu, J, Zhernakova, A, Weersma, R K

“…Abstract Background The pathogenesis of inflammatory bowel diseases is characterized by gastrointestinal dysbiosis. Small molecules -or metabolites- present in…”
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DOP53 In-depth characterisation of the serum antibody epitope repertoire in Inflammatory Bowel Disease by high-throughput phage-displayed immunoprecipitation sequencing by Bourgonje, A R, Andreu-Sánchez, S, Vogl, T, Hu, S, Vich Vila, A, Leviatan, S, Kurilshikov, A, Klompus, S, Kalka, I N, van Dullemen, H M, Weinberger, A, Visschedijk, M C, Festen, E A M, Faber, K N, Wijmenga, C, Dijkstra, G, Segal, E, Fu, J, Zhernakova, A, Weersma, R K

“…Abstract Background Patients with IBD show distinct antibody responses, particularly against microbiota. However, a comprehensive overview of the antibody…”
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GWAS of stool frequency provides insights into gastrointestinal motility and irritable bowel syndrome by Bonfiglio, Ferdinando, Liu, Xingrong, Smillie, Christopher, Pandit, Anita, Kurilshikov, Alexander, Bacigalupe, Rodrigo, Zheng, Tenghao, Nim, Hieu, Garcia-Etxebarria, Koldo, Bujanda, Luis, Andreasson, Anna, Agreus, Lars, Walter, Susanna, Abecasis, Gonçalo, Eijsbouts, Chris, Jostins, Luke, Parkes, Miles, Hughes, David A., Timpson, Nicholas, Raes, Jeroen, Franke, Andre, Kennedy, Nicholas A., Regev, Aviv, Zhernakova, Alexandra, Simren, Magnus, Camilleri, Michael, D’Amato, Mauro

“…Gut dysmotility is associated with constipation, diarrhea, and functional gastrointestinal disorders like irritable bowel syndrome (IBS), although its…”
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