Search Results - "Kurihara, Hiroaki"

Usefulness of carbon-11-labeled methionine positron-emission tomography for assessing the treatment response of primary central nervous system lymphoma by Miyakita, Yasuji, Ohno, Makoto, Takahashi, Masamichi, Kurihara, Hiroaki, Katai, Hitoshi, Narita, Yoshitaka

“…Primary central nervous system lymphoma (PCNSL) responds relatively quickly to chemotherapy or radiotherapy. However, determination of a complete response…”
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Identification and quantitative structure–activity relationship assessment of trace chemical impurities contained in the therapeutic formulation of [64Cu]Cu-ATSM by Igarashi, Chika, Matsumoto, Hiroki, Takahashi, Masashi, Hihara, Fukiko, Tachibana, Tomoko, Zhang, Ming-Rong, Kurihara, Hiroaki, Higashi, Tatsuya, Yoshii, Yukie

“…[64Cu]Cu-diacethyl-bis(N4-methylthiosemicarbazone) ([64Cu]Cu-ATSM) is a radioactive hypoxia-targeting therapeutic agent, and the efficacy and safety of…”
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Quantitative bone scan imaging using BSI and BUV: an approach to evaluate ARONJ early by Yamamoto, Yayoi, Mitsunaga, Sachiyo, Horikawa, Ayumi, Hino, Ayako, Kurihara, Hiroaki

“…Objective The usefulness of bone scan index (BSI), a quantitative metric of the area of uptake in computer-aided diagnosis in bone scintigraphy, has been…”
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64Cu2+ Complexes of Tripodal Amine Ligands’ In Vivo Tumor and Liver Uptakes and Intracellular Cu Distribution in the Extrahepatic Bile Duct Carcinoma Cell Line TFK-1: A Basic Comparative Study by Shinada, Mitsuhiro, Takahashi, Masashi, Igarashi, Chika, Matsumoto, Hiroki, Hihara, Fukiko, Tachibana, Tomoko, Oikawa, Masakazu, Suzuki, Hisashi, Zhang, Ming-Rong, Higashi, Tatsuya, Kurihara, Hiroaki, Yoshii, Yukie, Doi, Yoshihiro

“…Copper (Cu) is a critical element for cancer cell proliferation and considerably accumulates in the nucleus. 64Cu2+ is an anticancer radiopharmaceutical that…”
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Correlation between L-amino acid transporter 1 expression and 4-borono-2-18F-fluoro-phenylalanine accumulation in humans by Kashihara, Tairo, Mori, Taisuke, Nakaichi, Tetsu, Nakamura, Satoshi, Ito, Kimiteru, Kurihara, Hiroaki, Kusumoto, Masahiko, Itami, Jun, Yoshimoto, Seiichi, Igaki, Hiroshi

“…BackgroundThe correlation between L-type amino acid transporter 1 (LAT1) expression and 4-borono-2-18F-fluoro-phenylalanine (18F-FBPA) accumulation in humans…”
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Non‐invasive estimation of 10B‐4‐borono‐L‐phenylalanine‐derived boron concentration in tumors by PET using 4‐borono‐2‐18F‐fluoro‐phenylalanine by Yoshimoto, Mitsuyoshi, Honda, Natsuki, Kurihara, Hiroaki, Hiroi, Kenta, Nakamura, Satoshi, Ito, Masashi, Shikano, Naoto, Itami, Jun, Fujii, Hirofumi

“…In boron neutron capture therapy (BNCT), 10B‐4‐borono‐L‐phenylalanine (BPA) is commonly used as a 10B carrier. PET using 4‐borono‐2‐18F‐fluoro‐phenylalanine…”
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Evaluation of 64Cu-Labeled New Anti-EGFR Antibody NCAB001 with Intraperitoneal Injection for Early PET Diagnosis of Pancreatic Cancer in Orthotopic Tumor-Xenografted Mice and Nonhuman Primates by Matsumoto, Hiroki, Watabe, Tadashi, Igarashi, Chika, Tachibana, Tomoko, Hihara, Fukiko, Waki, Atsuo, Zhang, Ming-Rong, Tashima, Hideaki, Yamaya, Taiga, Ooe, Kazuhiro, Shimosegawa, Eku, Hatazawa, Jun, Yoshida, Sei, Naito, Kenichiro, Kurihara, Hiroaki, Ueno, Makoto, Ito, Kimiteru, Higashi, Tatsuya, Yoshii, Yukie

“…Objectives: To improve the prognosis of pancreatic cancer, new imaging methods to identify tumor lesions at a size of <1 cm are urgently needed. To approach…”
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In Vitro Tumor Cell-Binding Assay to Select High-Binding Antibody and Predict Therapy Response for Personalized 64Cu-Intraperitoneal Radioimmunotherapy against Peritoneal Dissemination of Pancreatic Cancer: A Feasibility Study by Hihara, Fukiko, Matsumoto, Hiroki, Yoshimoto, Mitsuyoshi, Masuko, Takashi, Endo, Yuichi, Igarashi, Chika, Tachibana, Tomoko, Shinada, Mitsuhiro, Zhang, Ming-Rong, Kurosawa, Gene, Sugyo, Aya, Tsuji, Atsushi B., Higashi, Tatsuya, Kurihara, Hiroaki, Ueno, Makoto, Yoshii, Yukie

“…Peritoneal dissemination of pancreatic cancer has a poor prognosis. We have reported that intraperitoneal radioimmunotherapy using a 64Cu-labeled antibody…”
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Process to Remove the Size Variants Contained in the Antibody–Chelator Complex PCTA-NCAB001 for Radiolabeling with Copper-64 by Yoshii, Yukie, Matsumoto, Hiroki, Igarashi, Chika, Tachibana, Tomoko, Hihara, Fukiko, Shinada, Mitsuhiro, Waki, Atsuo, Yoshida, Sei, Naito, Kenichiro, Ito, Kimiteru, Higashi, Tatsuya, Kurihara, Hiroaki, Ueno, Makoto

“…Understanding the physicochemical properties of antibody–drug conjugates is critical to assess their quality at manufacturing and monitor them during…”
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Characterization and Stabilization of a New 64Cu-Labeled Anti-EGFR Antibody NCAB001 for the Early Detection of Pancreatic Cancer with Positron Emission Tomography by Matsumoto, Hiroki, Igarashi, Chika, Tachibana, Tomoko, Hihara, Fukiko, Waki, Atsuo, Zhang, Ming-Rong, Yoshida, Sei, Naito, Kenichiro, Kurihara, Hiroaki, Ueno, Makoto, Ito, Kimiteru, Higashi, Tatsuya, Yoshii, Yukie

“…Early diagnosis of pancreatic cancer using current imaging modalities remains challenging. We have developed a new approach to identify tumor lesions ≥ 3 mm in…”
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Trace Metal Impurities Effects on the Formation of [ 64 Cu]Cu-diacetyl-bis( N 4 -methylthiosemicarbazone) ([ 64 Cu]Cu-ATSM) by Shinada, Mitsuhiro, Suzuki, Hisashi, Hanyu, Masayuki, Igarashi, Chika, Matsumoto, Hiroki, Takahashi, Masashi, Hihara, Fukiko, Tachibana, Tomoko, Sogawa, Chizuru, Zhang, Ming-Rong, Higashi, Tatsuya, Sato, Hidemitsu, Kurihara, Hiroaki, Yoshii, Yukie, Doi, Yoshihiro

“…[ Cu]Cu-diacetyl-bis( -methylthiosemicarbazone) ([ Cu]Cu-ATSM) is a radioactive hypoxia-targeting therapeutic agent being investigated in clinical trials for…”
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Radiation absorbed dose estimates for 18F-BPA PET by Kono, Yuzuru, Kurihara, Hiroaki, Kawamoto, Hiroshi, Yasui, Naoko, Honda, Naoki, Igaki, Hiroshi, Itami, Jun

“…Background Boron neutron capture therapy (BNCT) is a molecular radiation therapy approach based on the B (n, α) Li nuclear reaction in cancer cells. In BNCT,…”
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A case of pelvic squamous cell carcinoma of unknown primary origin that responded well to radiotherapy and nivolumab by Koge, Hiroaki, Hino, Ayako, Kakiuchi, Akira, Yamamoto, Yayoi, Kanbe, Akira, Kojima, Daichi, Horikawa, Ayumi, Doiuchi, Tsunehiro, Kurihara, Hiroaki

“…Squamous cell carcinoma of unknown primary origin in the pelvis is rare. We report a case of a 64-year-old woman with a large osteolytic squamous cell…”
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Theragnostic Imaging Using Radiolabeled Antibodies and Tyrosine Kinase Inhibitors by Yoshimoto, Mitsuyoshi, Fujii, Hirofumi, Kurihara, Hiroaki

“…During the past decade, the efficacy of new molecular targeted drugs such as tyrosine kinase inhibitors (TKIs) and monoclonal antibodies has been proven…”
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SMARCA4-deficient tumors in the adrenal gland and small intestines: A rare case report by Kambe, Akira, Yamamoto, Yayoi, Hasegawa, Chie, Kakiuchi, Akira, Kojima, Daichi, Hino, Ayako, Horikawa, Ayumi, Doiuchi, Tsunehiro, Kurihara, Hiroaki

“…Thoracic SMARCA4-deficient undifferentiated tumors (SMARCA4-UTs) are rare undifferentiated thoracic malignancies with poor prognosis. They predominantly affect…”
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Preclinical Safety Evaluation of Intraperitoneally Administered Cu-Conjugated Anti-EGFR Antibody NCAB001 for the Early Diagnosis of Pancreatic Cancer Using PET by Matsumoto, Hiroki, Igarashi, Chika, Tachibana, Tomoko, Hihara, Fukiko, Shinada, Mitsuhiro, Waki, Atsuo, Yoshida, Sei, Naito, Kenichiro, Kurihara, Hiroaki, Ueno, Makoto, Ito, Kimiteru, Higashi, Tatsuya, Yoshii, Yukie

“…Detecting tumor lesions <1 cm in size using current imaging methods remains a clinical challenge, especially in pancreatic cancer. Previously, we developed a…”
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SAPHO syndrome with a purely osteolytic form: A case report by Kakiuchi, Akira, Yamamoto, Yayoi, Kanbe, Akira, Kojima, Daichi, Hino, Ayako, Horikawa, Ayumi, Doiuchi, Tsunehiro, Kurihara, Hiroaki

“…SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome is a rare, chronic autoinflammatory disorder that can present with a constellation of…”
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A case of bulla formation after treatment for COVID-19 pneumonia by Murayama, Daisuke, Kojima, Daichi, Hino, Ayako, Yamamoto, Yayoi, Doiuchi, Tsunehiro, Horikawa, Ayumi, Kurihara, Hiroaki

“…In December 2019, coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was reported in Wuhan,…”
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Fluorodeoxyglucose positron emission tomography (FDG/PET) shows the effect of carbon-ion radiotherapy (CIRT); with pathologic confirmation by Aoki, Jun, Yamamoto, Yayoi, Horikawa, Ayumi, Doiuchi, Tsunehiro, Hino, Ayako, Kojima, Daichi, Kurihara, Hiroaki, Washimi, Kota, Katoh, Hiroyuki, Hiruma, Toru

“…Response evaluation of carbon-ion radiotherapy poses a diagnostic challenge. Due to its functional aspects, fluorodeoxyglucose positron emission tomography…”
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Analyzing spatial distribution between 18F-fluorodeoxyglucose and 18F-boronophenylalanine positron emission tomography to investigate selection indicators for boron neutron capture therapy by Nakaichi, Tetsu, Nakamura, Satoshi, Ito, Kimiteru, Takahashi, Kana, Takemori, Mihiro, Kashihara, Tairo, Kunito, Kouji, Murakami, Naoya, Iijima, Kotaro, Chiba, Takahito, Nakayama, Hiroki, Mikasa, Shohei, Nishio, Teiji, Okamoto, Hiroyuki, Itami, Jun, Kurihara, Hiroaki, Igaki, Hiroshi

“…Background 18 F-FDG PET is often utilized to determine BNCT selection due to the limited availability of 18 F-BPA PET, which is performed by synthesizing 18 F…”
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