Search Results - "Kurihara, Hidemi"

Molecular Mechanisms of Periodontal Disease by Kajiya, Mikihito, Kurihara, Hidemi

“…Periodontal disease, one of the most prevalent human infectious diseases, is characterized by chronic inflammatory tissue destruction of the alveolar bone and…”
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Effect of Porphyromonas gingivalis infection on gut dysbiosis and resultant arthritis exacerbation in mouse model by Hamamoto, Yuta, Ouhara, Kazuhisa, Munenaga, Syuichi, Shoji, Mikio, Ozawa, Tatsuhiko, Hisatsune, Jyunzo, Kado, Isamu, Kajiya, Mikihito, Matsuda, Shinji, Kawai, Toshihisa, Mizuno, Noriyoshi, Fujita, Tsuyoshi, Hirata, Shintaro, Tanimoto, Kotaro, Nakayama, Koji, Kishi, Hiroyuki, Sugiyama, Eiji, Kurihara, Hidemi

“…Abstract Background Porphyromonas gingivalis (Pg) infection causes periodontal disease and exacerbates rheumatoid arthritis (RA). It is reported that…”
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Regulation of osteogenesis via miR-101-3p in mesenchymal stem cells by human gingival fibroblasts by Kaneda-Ikeda, Eri, Iwata, Tomoyuki, Mizuno, Noriyoshi, Nagahara, Takayoshi, Kajiya, Mikihito, Ouhara, Kazuhisa, Yoshioka, Minami, Ishida, Shu, Kawaguchi, Hiroyuki, Kurihara, Hidemi

“…Introduction Mesenchymal stem cells (MSCs) can differentiate into various types of cells and can thus be used for periodontal regenerative therapy. However,…”
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Cox2-mediated PGE2 production via p38/JNK-c-fos signaling inhibits cell apoptosis in 3D floating culture clumps of mesenchymal stem cell/extracellular matrix complexes by Komatsu, Nao, Kajiya, Mikihito, Morimoto, Shin, Motoike, Souta, Yoshii, Hiroki, Iwata, Tomoyuki, Ouhara, Kazuhisa, Matsuda, Shinji, Mizuno, Noriyoshi, Kurihara, Hidemi

“…Mesenchymal stem cells (MSCs), a class of adult stem cells, have attracted scientific and medical attention due to their self-renewing properties,…”
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Rapid detection of the Streptococcus mutans cnm gene by loop-mediated isothermal amplification by Kitagawa, Masae, Nagamine, Kentaro, Oka, Hiroko, Ouhara, Kazuhisa, Ogawa, Ikuko, Komatsuzawa, Hitoshi, Kurihara, Hidemi

“…This study investigated a method using loop-mediated isothermal amplification (LAMP) for the rapid detection of cnm-positive Streptococcus mutans (S. mutans)…”
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Dental infection of Porphyromonas gingivalis exacerbates high fat diet-induced steatohepatitis in mice by Furusho, Hisako, Miyauchi, Mutsumi, Hyogo, Hideyuki, Inubushi, Toshihiro, Ao, Min, Ouhara, Kazuhisa, Hisatune, Junzou, Kurihara, Hidemi, Sugai, Motoyuki, Hayes, C. Nelson, Nakahara, Takashi, Aikata, Hiroshi, Takahashi, Shoichi, Chayama, Kazuaki, Takata, Takashi

“…Background We investigated the effects of dental infection with Porphyromonas gingivalis ( P.g. ), an important periodontal pathogen, on NASH progression, by…”
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Periodontal inflamed surface area in oral cavity associated with febrile neutropenia in patients with hematologic malignancy undergoing chemotherapy by Nishi, Hiromi, Ohta, Kouji, Kuramoto, Yuri, Shigeishi, Hideo, Obayashi, Taiji, Yoshioka, Yukio, Konishi, Masaru, Munenaga, Shuichi, Nagoshi, Hisao, Yoshida, Tetsumi, Fukushima, Noriyasu, Kakimoto, Naoya, Ohge, Hiroki, Kurihara, Hidemi, Ichinohe, Tatsuo, Kawaguchi, Hiroyuki

“…Febrile neutropenia (FN) is an infectious complication that develops during chemotherapy. Although the oral cavity can be an important infection route, it is…”
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Alveolar Bone Protection by Targeting the SH3BP2‐SYK Axis in Osteoclasts by Kittaka, Mizuho, Yoshimoto, Tetsuya, Schlosser, Collin, Rottapel, Robert, Kajiya, Mikihito, Kurihara, Hidemi, Reichenberger, Ernst J, Ueki, Yasuyoshi

“…ABSTRACT Periodontitis is a bacterially induced chronic inflammatory condition of the oral cavity where tooth‐supporting tissues including alveolar bone are…”
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The role of nuclear receptor 4A1 (NR4A1) in drug‐induced gingival overgrowth by Hatano, Saki, Matsuda, Shinji, Okanobu, Ai, Furutama, Daisuke, Memida, Takumi, Kajiya, Mikihito, Ouhara, Kazuhisa, Fujita, Tsuyoshi, Mizuno, Noriyoshi, Kurihara, Hidemi

“…Drug‐induced gingival overgrowth (DIGO) is a side effect of cyclosporine A (CsA), nifedipine (NIF), and phenytoin (PHT). Nuclear receptor 4A1 (NR4A1) plays a…”
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Randomized Placebo‐Controlled and Controlled Non‐Inferiority Phase III Trials Comparing Trafermin, a Recombinant Human Fibroblast Growth Factor 2, and Enamel Matrix Derivative in Periodontal Regeneration in Intrabony Defects by Kitamura, Masahiro, Akamatsu, Motoki, Kawanami, Masamitsu, Furuichi, Yasushi, Fujii, Takeo, Mori, Mari, Kunimatsu, Kazushi, Shimauchi, Hidetoshi, Ogata, Yorimasa, Yamamoto, Matsuo, Nakagawa, Taneaki, Sato, Shuichi, Ito, Koichi, Ogasawara, Takefumi, Izumi, Yuichi, Gomi, Kazuhiro, Yamazaki, Kazuhisa, Yoshie, Hiromasa, Fukuda, Mitsuo, Noguchi, Toshihide, Takashiba, Shogo, Kurihara, Hidemi, Nagata, Toshihiko, Hamachi, Takafumi, Maeda, Katsumasa, Yokota, Makoto, Sakagami, Ryuji, Hara, Yoshitaka, Noguchi, Kazuyuki, Furuuchi, Toshi, Sasano, Takashi, Imai, Enyu, Ohmae, Masatoshi, Koizumi, Hayuru, Watanuki, Mitsuru, Murakami, Shinya

“…ABSTRACT We investigated the efficacy, safety, and clinical significance of trafermin, a recombinant human fibroblast growth factor (rhFGF)‐2, for periodontal…”
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Masticatory dysfunction in patients with diabetic neuropathy: A cross-sectional study by Hamamoto, Yuta, Ouhara, Kazuhisa, Miyagawa, Tsuyoshi, Shintani, Tomoaki, Komatsu, Nao, Kajiya, Mikihito, Matsuda, Shinji, Fujita, Tsuyoshi, Sasaki, Shinya, Iwata, Tomoyuki, Ohno, Haruya, Yoneda, Masayasu, Mizuno, Noriyoshi, Kurihara, Hidemi

“…Chewing well is essential for successful diet therapy and control of blood glucose level in patients with diabetes. In addition, long-term hyperglycemia is a…”
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Glycyrrhizic acid suppresses inflammation and reduces the increased glucose levels induced by the combination of Porphyromonas gulae and ligature placement in diabetic model mice by Akutagawa, Keiichi, Fujita, Tsuyoshi, Ouhara, Kazuhisa, Takemura, Tasuku, Tari, Misako, Kajiya, Mikihito, Matsuda, Shinji, Kuramitsu, Shohei, Mizuno, Noriyoshi, Shiba, Hideki, Kurihara, Hidemi

“…Diabetic patients are at an increased risk of developing severe and progressive periodontitis. Periodontal disease also increases the severity of diabetes by…”
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Association between periodontal disease due to Campylobacter rectus and cerebral microbleeds in acute stroke patients by Shiga, Yuji, Hosomi, Naohisa, Nezu, Tomohisa, Nishi, Hiromi, Aoki, Shiro, Nakamori, Masahiro, Ishikawa, Kenichi, Kinoshita, Naoto, Imamura, Eiji, Ueno, Hiroki, Shintani, Tomoaki, Ohge, Hiroki, Kawaguchi, Hiroyuki, Kurihara, Hidemi, Wakabayashi, Shinichi, Maruyama, Hirofumi, Fletcher, Hansel McClear

“…Oral health conditions and cerebral small vessel disease, such as white matter lesions or cerebral microbleeds (CMBs), are associated with the incidence of…”
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Regulation of defensive function on gingival epithelial cells can prevent periodontal disease by Fujita, Tsuyoshi, Yoshimoto, Tetsuya, Kajiya, Mikihito, Ouhara, Kazuhisa, Matsuda, Shinji, Takemura, Tasuku, Akutagawa, Keiichi, Takeda, Katsuhiro, Mizuno, Noriyoshi, Kurihara, Hidemi

“…Periodontal disease is a bacterial biofilm-associated inflammatory disease that has been implicated in many systemic diseases. A new preventive method for…”
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Serum IgG titers to periodontal pathogens predict 3-month outcome in ischemic stroke patients by Aoki, Shiro, Hosomi, Naohisa, Nishi, Hiromi, Nakamori, Masahiro, Nezu, Tomohisa, Shiga, Yuji, Kinoshita, Naoto, Ueno, Hiroki, Ishikawa, Kenichi, Imamura, Eiji, Shintani, Tomoaki, Ohge, Hiroki, Kawaguchi, Hiroyuki, Kurihara, Hidemi, Maruyama, Hirofumi

“…Several cohort studies have shown that periodontal disease is associated with an increased risk for stroke. However, it remains unclear whether serum antibody…”
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Aggressive periodontitis and NOD2 variants by Mizuno, Noriyoshi, Kume, Kodai, Nagatani, Yukiko, Matsuda, Shinji, Iwata, Tomoyuki, Ouhara, Kazuhisa, Kajiya, Mikihito, Takeda, Katsuhiro, Matsuda, Yukiko, Tada, Yui, Ohsawa, Ryosuke, Morino, Hiroyuki, Mihara, Keichiro, Fujita, Tsuyoshi, Kawaguchi, Hiroyuki, Shiba, Hideki, Kawakami, Hideshi, Kurihara, Hidemi

“…Aggressive periodontitis (AgP) occurs at an early age and causes rapid periodontal tissue destruction. Nucleotide-binding oligomerization domain-containing…”
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BDNF/HMW‐HA complex as an adjunct to nonsurgical periodontal treatment of ligature‐induced periodontitis in dogs by Sasaki, Shinya, Takeda, Katsuhiro, Takewaki, Manabu, Ouhara, Kazuhisa, Kajiya, Mikihito, Mizuno, Noriyoshi, Fujita, Tsuyoshi, Kurihara, Hidemi

“…Background Recently, brain‐derived neurotrophic factor (BDNF)/high molecular weight hyaluronic acid (HMW‐HA) complex with flap surgery has been shown to…”
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The involvement of C5a in the progression of experimental arthritis with Porphyromonas gingivalis infection in SKG mice by Munenaga, Syuichi, Ouhara, Kazuhisa, Hamamoto, Yuta, Kajiya, Mikihito, Takeda, Katsuhiro, Yamasaki, Satoshi, Kawai, Toshihisa, Mizuno, Noriyoshi, Fujita, Tsuyoshi, Sugiyama, Eiji, Kurihara, Hidemi

“…Epidemiological evidence to suggest that periodontal disease (PD) is involved in the progression of rheumatoid arthritis (RA) is increasing. The complement…”
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Clumps of Mesenchymal Stem Cell/Extracellular Matrix Complexes Generated with Xeno-Free Conditions Facilitate Bone Regeneration via Direct and Indirect Osteogenesis by Motoike, Souta, Kajiya, Mikihito, Komatsu, Nao, Horikoshi, Susumu, Ogawa, Tomoya, Sone, Hisakatsu, Matsuda, Shinji, Ouhara, Kazuhisa, Iwata, Tomoyuki, Mizuno, Noriyoshi, Fujita, Tsuyoshi, Ikeya, Makoto, Kurihara, Hidemi

“…Three-dimensional clumps of mesenchymal stem cell (MSC)/extracellular matrix (ECM) complexes (C-MSCs) consist of cells and self-produced ECM. We demonstrated…”
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Relationship of oral bacterial number with medical hospitalization costs in analysis of Diagnosis Procedure Combination database from single institution in Japan by Nishi, Hiromi, Kajiya, Mikihito, Ohta, Kouji, Shigeishi, Hideo, Obayashi, Taiji, Munenaga, Syuichi, Obayashi, Nami, Yoshioka, Yukio, Konishi, Masaru, Naruse, Takako, Matsumoto, Akihiro, Odo, Ayaka, Kitagawa, Masae, Ando, Toshinori, Shintani, Tomoaki, Tokikazu, Tomoko, Ino, Natsumi, Mihara, Naoki, Kakimoto, Naoya, Tsuga, Kazuhiro, Tanimoto, Kotaro, Ohge, Hiroki, Kurihara, Hidemi, Kawaguchi, Hiroyuki

“…Oral bacteria are known to be associated with perioperative complications during hospitalization. However, no presented reports have clarified the relationship…”
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