Search Results - "Kure, Elin"

Differential expression of miRNAs in colorectal cancer: comparison of paired tumor tissue and adjacent normal mucosa using high-throughput sequencing by Hamfjord, Julian, Stangeland, Astrid M, Hughes, Timothy, Skrede, Martina L, Tveit, Kjell M, Ikdahl, Tone, Kure, Elin H

“…We present the results of a global study of dysregulated miRNAs in paired samples of normal mucosa and tumor from eight patients with colorectal cancer…”
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Circulating microRNAs associated with prolonged overall survival in lung cancer patients treated with nivolumab by Halvorsen, Ann Rita, Sandhu, Vandana, Sprauten, Mette, Flote, Vidar G, Kure, Elin H, Brustugun, Odd Terje, Helland, Åslaug

“…The introduction of immune check-point inhibition in non-small cell lung cancer (NSCLC) therapy represents improved prospects for the patients. The response…”
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Prognostic role of carcinoembryonic antigen and carbohydrate antigen 19-9 in metastatic colorectal cancer: a BRAF-mutant subset with high CA 19-9 level and poor outcome by Thomsen, Maria, Skovlund, Eva, Sorbye, Halfdan, Bolstad, Nils, Nustad, Kjell Johannes, Glimelius, Bengt, Pfeiffer, Per, Kure, Elin H., Johansen, Julia S., Tveit, Kjell Magne, Christoffersen, Thoralf, Guren, Tormod Kyrre

“…Background Mutation status of RAS and BRAF , as well as serum levels of carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA 19-9), are biomarkers…”
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Clinicopathological factors associated with tumour‐specific mutation detection in plasma of patients with RAS‐mutated or BRAF‐mutated metastatic colorectal cancer by Hamfjord, Julian, Guren, Tormod Kyrre, Glimelius, Bengt, Sorbye, Halfdan, Pfeiffer, Per, Dajani, Olav, Lingjærde, Ole Christian, Tveit, Kjell Magne, Pallisgaard, Niels, Spindler, Karen‐Lise Garm, Kure, Elin H.

“…Detection of tumour‐specific circulating cell‐free DNA in plasma (ctDNA) fails in a significant number of cases depending on the clinical context. The primary…”
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Integrative pan-cancer analysis reveals a common architecture of dysregulated transcriptional networks characterized by loss of enhancer methylation by Ankill, Jørgen, Zhao, Zhi, Tekpli, Xavier, Kure, Elin H., Kristensen, Vessela N., Mathelier, Anthony, Fleischer, Thomas

“…Aberrant DNA methylation contributes to gene expression deregulation in cancer. However, these alterations’ precise regulatory role and clinical implications…”
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Survival Trends of Right- and Left-Sided Colon Cancer across Four Decades: A Norwegian Population-Based Study by Hamfjord, Julian, Myklebust, Tor Åge, Larsen, Inger Kristin, Kure, Elin H, Glimelius, Bengt, Guren, Tormod K, Tveit, Kjell M, Guren, Marianne G

“…Patients with right-sided colon cancer (RCC) and left-sided colon cancer (LCC) differ clinically and molecularly. The main objective was to investigate…”
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Circulating tumour DNA and its clinical utility in predicting treatment response or survival in patients with metastatic colorectal cancer: a systematic review and meta-analysis by Callesen, Louise B., Hamfjord, Julian, Boysen, Anders K., Pallisgaard, Niels, Guren, Tormod K., Kure, Elin H., Spindler, Karen-Lise G.

“…Background We investigate the current knowledge on circulating tumour DNA (ctDNA) and its clinical utility in predicting outcomes in patients with metastatic…”
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Impact of early disease progression and surgical complications on adjuvant chemotherapy completion rates and survival in patients undergoing the surgery first approach for resectable pancreatic ductal adenocarcinoma - A population-based cohort study by Labori, Knut J, Katz, Matthew H, Tzeng, Ching W, Bjørnbeth, Bjørn A, Cvancarova, Milada, Edwin, Bjørn, Kure, Elin H, Eide, Tor J, Dueland, Svein, Buanes, Trond, Gladhaug, Ivar P

“…Multimodality treatment (MMT) improves survival for patients with pancreatic ductal adenocarcinoma (PDAC). The surgery-first (SF) strategy is the most…”
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High ABCC2 and low ABCG2 gene expression are early events in the colorectal adenoma-carcinoma sequence by Andersen, Vibeke, Vogel, Lotte K, Kopp, Tine Iskov, Sæbø, Mona, Nonboe, Annika W, Hamfjord, Julian, Kure, Elin H, Vogel, Ulla

“…Development of colorectal cancer (CRC) may result from a dysfunctional interplay between diet, gut microbes and the immune system. The ABC transport proteins…”
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Molecular characterisation of TP53 mutated squamous cell carcinomas of the lung to identify putative targets for therapy by Haakensen, Vilde D., Khadse, Anand, Sandhu, Vandana, Halvorsen, Ann Rita, Solberg, Steinar K., Jørgensen, Lars H., Brustugun, Odd Terje, Kure, Elin H., Helland, Åslaug

“…Personalised cancer treatment depends on identification of therapeutically relevant biological subgroups of patients for assessing effect of treatment and to…”
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Cetuximab in treatment of metastatic colorectal cancer: final survival analyses and extended RAS data from the NORDIC-VII study by Guren, Tormod Kyrre, Thomsen, Maria, Kure, Elin H, Sorbye, Halfdan, Glimelius, Bengt, Pfeiffer, Per, Österlund, Pia, Sigurdsson, Fridbjörn, Lothe, Inger Marie Bowitz, Dalsgaard, Astrid Marie, Skovlund, Eva, Christoffersen, Thoralf, Tveit, Kjell Magne

“…Background: The NORDIC-VII study is a randomised phase III trial of cetuximab plus continuous or intermittent fluorouracil, folinic acid, and oxaliplatin…”
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Phase III Trial of Cetuximab With Continuous or Intermittent Fluorouracil, Leucovorin, and Oxaliplatin (Nordic FLOX) Versus FLOX Alone in First-Line Treatment of Metastatic Colorectal Cancer: The NORDIC-VII Study by MAGNE TVEIT, Kjell, GUREN, Tormod, FOKSTUEN, Tone, HANSEN, Flemming, HOFSLI, Eva, BIRKEMEYER, Elke, JOHNSSON, Anders, STARKHAMMAR, Hans, YILMAZ, Mette Karen, KELDSEN, Nina, BERIT ERDAL, Anne, DAJANI, Olav, GLIMELIUS, Bengt, DAHL, Olav, CHRISTOFFERSEN, Thoralf, PFEIFFER, Per, SORBYE, Halfdan, PYRHONEN, Seppo, SIGURDSSON, Fridbjorn, KURE, Elin, IKDAHL, Tone, SKOVLUND, Eva

“…The NORDIC-VII multicenter phase III trial investigated the efficacy of cetuximab when added to bolus fluorouracil/folinic acid and oxaliplatin (Nordic FLOX),…”
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Interleukin-6 and C-reactive protein as prognostic biomarkers in metastatic colorectal cancer by Thomsen, Maria, Kersten, Christian, Sorbye, Halfdan, Skovlund, Eva, Glimelius, Bengt, Pfeiffer, Per, Johansen, Julia S, Kure, Elin H, Ikdahl, Tone, Tveit, Kjell Magne, Christoffersen, Thoralf, Guren, Tormod Kyrre

“…The aim was to explore the prognostic significance of IL-6 and markers of systemic inflammatory response (SIR), in particular C-reactive protein (CRP), in…”
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Intestinal PTGS2 mRNA levels, PTGS2 gene polymorphisms, and colorectal carcinogenesis by Vogel, Lotte K, Sæbø, Mona, Høyer, Helle, Kopp, Tine Iskov, Vogel, Ulla, Godiksen, Sine, Frenzel, Franz B, Hamfjord, Julian, Bowitz-Lothe, Inger Marie, Johnson, Egil, Kure, Elin H, Andersen, Vibeke

“…Inflammation is a major risk factor for development of colorectal cancer (CRC). Prostaglandin synthase cyclooxygenase-2 (COX-2) encoded by the PTGS2 gene is…”
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Let-7 miRNA-binding site polymorphism in the KRAS 3′UTR; colorectal cancer screening population prevalence and influence on clinical outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin +/− cetuximab by Kjersem, Janne B, Ikdahl, Tone, Guren, Tormod, Skovlund, Eva, Sorbye, Halfdan, Hamfjord, Julian, Pfeiffer, Per, Glimelius, Bengt, Kersten, Christian, Solvang, Hiroko, Tveit, Kjell M, Kure, Elin H

“…Abstract Background Recent studies have reported associations between a variant allele in a let-7 microRNA complementary site (LCS6) within the 3 ′…”
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Generation and characterisation of novel pancreatic adenocarcinoma xenograft models and corresponding primary cell lines by Wennerström, Anna B, Lothe, Inger Marie Bowitz, Sandhu, Vandana, Kure, Elin H, Myklebost, Ola, Munthe, Else

“…Pancreatic adenocarcinoma is one of the most lethal cancer types, currently lacking efficient treatment. The heterogeneous nature of these tumours are poorly…”
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Clinical relevance of pancreatobiliary and intestinal subtypes of ampullary and duodenal adenocarcinoma: Pattern of recurrence, chemotherapy, and survival after pancreatoduodenectomy by Bowitz Lothe, Inger Marie, Kleive, Dyre, Pomianowska, Ewa, Cvancarova, Milada, Kure, Elin, Dueland, Svein, Gladhaug, Ivar P., Labori, Knut Jørgen

“…The clinical relevance of the classification of ampullary adenocarcinoma (AC) into pancreatobiliary (PB) or intestinal (Int) subtypes has not been resolved…”
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Prognostic Significance of the Loss of Heterozygosity of KRAS in Early-Stage Lung Adenocarcinoma by Khadse, Anand, Haakensen, Vilde D, Silwal-Pandit, Laxmi, Hamfjord, Julian, Micke, Patrick, Botling, Johan, Brustugun, Odd Terje, Lingjærde, Ole Christian, Helland, Åslaug, Kure, Elin H

“…Lung cancer is a common disease with a poor prognosis. Genomic alterations involving the gene are common in lung carcinomas, although much is unknown about how…”
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Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver by Costa-Silva, Bruno, Aiello, Nicole M., Ocean, Allyson J., Singh, Swarnima, Zhang, Haiying, Thakur, Basant Kumar, Becker, Annette, Hoshino, Ayuko, Mark, Milica Tešić, Molina, Henrik, Xiang, Jenny, Zhang, Tuo, Theilen, Till-Martin, García-Santos, Guillermo, Williams, Caitlin, Ararso, Yonathan, Huang, Yujie, Rodrigues, Gonçalo, Shen, Tang-Long, Labori, Knut Jørgen, Lothe, Inger Marie Bowitz, Kure, Elin H., Hernandez, Jonathan, Doussot, Alexandre, Ebbesen, Saya H., Grandgenett, Paul M., Hollingsworth, Michael A., Jain, Maneesh, Mallya, Kavita, Batra, Surinder K., Jarnagin, William R., Schwartz, Robert E., Matei, Irina, Peinado, Héctor, Stanger, Ben Z., Bromberg, Jacqueline, Lyden, David

“…Pancreatic ductal adenocarcinomas (PDACs) are highly metastatic with poor prognosis, mainly due to delayed detection. We hypothesized that intercellular…”
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The level of claudin-7 is reduced as an early event in colorectal carcinogenesis by Bornholdt, Jette, Friis, Stine, Godiksen, Sine, Poulsen, Steen S, Santoni-Rugiu, Eric, Bisgaard, Hanne C, Lothe, Inger M B, Ikdahl, Tone, Tveit, Kjell M, Johnson, Egil, Kure, Elin H, Vogel, Lotte K

“…Compromised epithelial barriers are found in dysplastic tissue of the gastrointestinal tract. Claudins are transmembrane proteins important for tight…”
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