Search Results - "Kurasawa, H"
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Chemically Defined, High-Density Insect Cell-Based Expression System for Scalable AAV Vector Production
Published in Molecular therapy. Methods & clinical development (11-12-2020)“…The recombinant adeno-associated virus (AAV) vector is one of the most utilized viral vectors in gene therapy due to its robust, long-term in vivo transgene…”
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Cluster III of Low-Density Lipoprotein Receptor-Related Protein 1 Binds Activated Blood Coagulation Factor VIII
Published in Biochemistry (Easton) (20-01-2015)“…Low-density lipoprotein receptor-related protein 1 (LRP) mediates clearance of blood coagulation factor VIII (FVIII). In LRP, FVIII binds the complement-type…”
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Mapping the Binding Region on the Low Density Lipoprotein Receptor for Blood Coagulation Factor VIII
Published in The Journal of biological chemistry (26-07-2013)“…Low density lipoprotein receptor (LDLR) was shown to mediate clearance of blood coagulation factor VIII (FVIII) from the circulation. To elucidate the…”
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Commutators of the four-current and sum rules in relativistic nuclear models
Published in Progress of theoretical and experimental physics (01-04-2013)“…There is a long-standing problem with the linearly energy-weighted sum of the excitation strengths in relativistic field theory and nuclear models: The sum…”
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Molecular chaperone RAP interacts with LRP1 in a dynamic bivalent mode and enhances folding of ligand-binding regions of other LDLR family receptors
Published in The Journal of biological chemistry (01-07-2021)“…The low-density lipoprotein receptor (LDLR) family of receptors are cell-surface receptors that internalize numerous ligands and play crucial role in various…”
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Characterization of interaction between blood coagulation factor VIII and LRP1 suggests dynamic binding by alternating complex contacts
Published in Journal of thrombosis and haemostasis (01-10-2022)“…Deficiency in blood coagulation factor VIII (FVIII) results in life‐threating bleeding (hemophilia A) treated by infusions of FVIII concentrates. To improve…”
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Exciton delocalization length of merocyanine J-aggregates in Langmuir–Blodgett films studied from linear and nonlinear absorption measurements
Published in Chemical physics letters (09-09-2002)“…A delocalization length and dimensionality of Frenkel excitons in 6-methyl merocyanine J-aggregates in Langmuir–Blodgett films have been investigated by means…”
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Hysteresis-like binding of coagulation factors X/Xa to procoagulant activated platelets and phospholipids results from multistep association and membrane-dependent multimerization
Published in Biochimica et biophysica acta (01-06-2016)“…Binding of coagulation factors X (fX) and Xa (fXa) to activated platelets is required for the formation of membrane-dependent enzymatic complexes of intrinsic…”
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Role of the Dirac sea in the quenching of Gamow-Teller strength
Published in Physical review letters (08-08-2003)“…The issue of the Gamow-Teller sum rule in atomic nuclei is reexamined in the framework of a relativistic description of nuclei. It is shown that the total…”
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Expression and characterization of a codon‐optimized blood coagulation factor VIII
Published in Journal of thrombosis and haemostasis (01-04-2017)“…Essentials Recombinant factor VIII (FVIII) is known to be expressed at a low level in cell culture. To increase expression, we used codon‐optimization of a…”
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The Gamow-Teller states and sum rule in relativistic models
Published in Nuclear Physics A (09-02-2004)“…The giant Gamow-Teller(GT) states and the CT sum rule are investigated in relativistic models. It is shown that the Ikeda-Fujii-Fujita sum rule value is…”
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Hierarchical structure of merocyanine J-aggregates prepared by Langmuir–Blodgett and spin-coating methods
Published in Colloids and surfaces. A, Physicochemical and engineering aspects (05-05-2005)“…We have investigated structures of 6-methyl merocyanine (6Me-DS) J-aggregates self-assembled in Langmuir–Blodgett (LB) films and spin-coated polyvinyl alcohol…”
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The mean energy, strength and width of the double giant dipole states
Published in Nuclear physics. A (05-02-1996)“…Model-independent sum rules for an excitation strength of the “double” giant dipole resonance state are derived. The strength is given in terms of that for the…”
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Femtosecond transient absorption study of merocyanine J-aggregates
Published in Journal of luminescence (01-12-2001)“…A delocalization length and dimensionality of Frenkel excitons in 6-methyl merocyanine J-aggregates in Langumuir–Blodgett films have been investigated by means…”
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Journal Article Conference Proceeding -
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Insect cell-based expression and characterization of a single-chain variable antibody fragment directed against blood coagulation factor VIII
Published in Protein expression and purification (01-04-2013)“…A recombinant single-chain variable antibody fragment (scFv) KM33 was previously described as a ligand that can inhibit the function of blood coagulation…”
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Sum rules of the multiple giant resonance states
Published in Progress of theoretical physics (01-10-2005)Get full text
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Roles of antinucleon degrees of freedom in the relativistic random phase approximation
Published in Progress of theoretical and experimental physics (01-11-2015)“…The roles of antinucleon degrees of freedom in the relativistic random phase approximation (RPA) are investigated. The energy-weighted sum of the RPA…”
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Part I: Further evolution of a literature database: the international use of a common software structure and methodology for the establishment of national consultation/liaison databases
Published in General hospital psychiatry (01-11-1999)“…Every day there are 6000–7000 papers published in science. Since the C-L psychiatrist may be asked to consult on a patient with any medical illness, and who…”
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Off-pump versus standard on-pump reoperative coronary artery bypass grafting
Published in Kyobu geka. The Japanese journal of thoracic surgery (01-07-2003)“…Using standard on-pump procedures, repeat coronary artery bypass grafting (re-CABGs) are associated with a higher morbidity and mortality than first-time…”
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